Are Hypochlorous Acid (HOCl) Sprays Safe During Pregnancy?
Hypochlorous acid (HOCl) is a gentle antimicrobial used in dermatology to calm redness, support wound care, and reduce breakout-causing bacteria. Topical HOCl mists are generally low risk in pregnancy because they act on the skin surface and are non-sensitising. They shine as a calming step between cleansing and moisturising, especially for reactive or acne-prone skin.
Quick verdict
- Safe-leaning, fragrance-free calming step.
- Not a stand-alone acne treatment; pair with pregnancy-friendly actives if needed.
- Use on intact skin; avoid spraying into eyes or on open wounds.
HOCl-friendly routine anchors (brand - name - safety score - notes)
- 111MedCo 0.02% Hypochlorous Acid Face & Body Microbial Cleanser (score 100) - HOCl spray/cleanser to calm flare-ups.
- Bambu Earth Rosewater Cleanser (score 100) - gentle cleanse before HOCl.
- Apotheke Pure Castille Facial Wash (score 100) - simple base; dilute if dry.
- La Roche-Posay Anthelios Mineral One SPF 50+ Tinted Sunscreen (score 76) - mineral SPF to prevent post-acne marks.
- Doctor Rogers RESTORE® Restore Healing Balm (score 100) - seal moisture after irritation.
How to use HOCl in your routine
- AM: Gentle cleanser -> HOCl spray -> Moisturiser -> Mineral SPF 50.
- Midday: Reapply HOCl on sweaty or mask-prone areas if skin feels irritated; then reapply SPF.
- PM: Gentle cleanser -> HOCl spray -> (If approved) azelaic acid or sulfur on spots -> Moisturiser.
- Body/Back: Spray after shower on intact skin; moisturise after if dry.
When to add other actives
- For stubborn acne, low-strength benzoyl peroxide or azelaic acid can be added with clinician approval.
- For seborrheic dermatitis, HOCl can be calming, but medicated shampoos may still be needed?ask your clinician.
FAQs in plain language
- Can I overuse HOCl? It is gentle, but if skin feels tight, follow with moisturiser and reduce frequency.
- Is HOCl bleaching? No. It should not bleach fabrics or skin when used as directed.
- Safe while breastfeeding? Generally acceptable topically; avoid areas an infant could ingest.
References to share with your clinician
- American Academy of Dermatology on pregnancy skin care: https://www.aad.org/public/everyday-care/pregnancy/skin-care/skin-care-pregnancy
- ACOG on acne during pregnancy: https://www.acog.org/womens-health/faqs/acne-during-pregnancy
- NHS on skin changes in pregnancy: https://www.nhs.uk/pregnancy/related-conditions/common-symptoms/skin-changes/
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FAQs
Is hypochlorous acid safe in pregnancy?
Topical HOCl sprays are generally considered low risk and are used to calm irritated or breakout-prone skin.
Can I spray HOCl on open skin?
Avoid open wounds; use on intact skin and follow label directions.
Do I still need other actives?
HOCl is calming but not a full acne routine. Pair with azelaic acid or benzoyl peroxide if your clinician approves.


