Neutrogena
Neutrogena Hydro Boost Water Cream Fragrance Free
Low risk79/100
Neutrogena
Hydro Boost Gel Cream
Some ingredients carry a low-risk flag. Read the formulation context before deciding.
34 of 34 ingredients rated
Is it suitable during pregnancy?
MamaSkin rates the recorded formula for Neutrogena Hydro Boost Gel Cream as Low risk (78/100). Review the ingredient context and any manual-review explanation before deciding.
Why this rating?
The recorded formula includes 2 ingredient entries with risk flags: Dimethicone (Low risk), Dimethicone Crosspolymer (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail.
34 of 34 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
How we assess productsIngredient breakdown
The recorded formula, with evidence behind each rating. Unmatched ingredients are marked Not assessed in grey.
Ingredient ratings and evidence
Higher-risk flags first. Open an ingredient for evidence.
Dimethicone
Low risk
Dimethicone is a silicone polymer used as a skin protectant and slip/conditioning agent. It is considered inert with minimal dermal absorption; the main practical issues are cosmetic (feel) and occasional irritation in very sensitive users. It is not a pregnancy-specific concern in topical cosmetic use.
Sources: CIR: Amended Safety Assessment of Dimethicone, Methicone, and Substituted-Methicone Polymers as Used in Cosmetics https://cir-safety.org/supplementaldoc/amended-safety-assessment-dimethicone-methicone-and-substituted-methicone-polymers-2
Dimethicone Crosspolymer
Low risk
This ingredient is a dimethicone crosspolymer covered by CIR's crosspolymer assessment. CIR concluded the reviewed crosspolymers safe as used in cosmetics. That conclusion is based on polymer chemistry and cosmetic-use safety data, not human pregnancy studies for every named crosspolymer. MamaSkin retains Low Risk; finished-product irritation remains formulation-dependent.
Sources: CIR: Safety assessment of dimethicone crosspolymers https://www.cir-safety.org/supplementaldoc/safety-assessment-dimethicone-crosspolymers-used-cosmetics
Water
No known risks
Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en
Glycerin
No known risks
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Cetearyl Olivate
No known risks
Emollient ester/emulsifier used to improve skin feel and stabilise emulsions. Reviewed cosmetic safety sources support topical cosmetic use; the relevant practical caveat is formulation irritation potential rather than a pregnancy-specific concern.
Sources: CIR: Amended Safety Assessment of Alkyl Esters as Used in Cosmetics; CIR Quick Reference Table (Cetearyl Olivate); EU CosIng / cosmetics regulatory inventory
Show all 34 ingredients
Sorbitan Olivate
No known risks
Olive-derived sorbitan ester used as an emulsifier and skin-conditioning ingredient. Reviewed cosmetic safety references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.
Sources: CIR: Safety Assessment of Sorbitan Esters as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Sodium Hyaluronate
No known risks
Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Serine
No known risks
Amino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Glycine
No known risks
Amino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Alanine
No known risks
Amino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Threonine
No known risks
Amino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Arginine
No known risks
Amino acid used as a humectant, skin-conditioning agent, and pH-adjusting support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of α-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Proline
No known risks
Amino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Lysine Hcl
No known risks
An amino acid or amino-acid salt used for conditioning, buffering or hydration. Cosmetic safety reviewers concluded that the assessed animal- and plant-derived amino acids are safe in current practices of use and concentration. No pregnancy-specific concern was identified for normal topical exposure.
Sources: CIR: Safety Assessment of Animal- and Plant-Derived Amino Acids as Used in Cosmetics; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
Glutamic Acid
No known risks
This naturally occurring alpha-amino acid is used for humectancy and skin or hair conditioning. The Cosmetic Ingredient Review found alpha-amino acids safe in current cosmetic use; the low concentrations and limited dermal uptake are not expected to create a pregnancy- or breastfeeding-specific concern.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-%CE%B1-amino-acids-used-cosmetics
Sodium PCA
No known risks
Natural-moisturising-factor humectant that helps bind water in the stratum corneum. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of PCA and Its Salts as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
PCA
No known risks
Pyrrolidone carboxylic acid, a natural-moisturising-factor component used as a humectant. Cosmetic safety reviewers concluded that PCA and its salts are safe in current practices, but they should not be used in formulations where N-nitroso compounds can form. No pregnancy-specific concern was identified for compliant topical use.
Sources: CIR: Safety Assessment of PCA and Its Salts as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-pca-2-pyrrolidone-5-carboxylic-acid-and-its-salts-used-cosmetics-0
Sodium Lactate
No known risks
Humectant and buffer that also forms part of the skin's natural moisturising factor. Reviewed cosmetic safety sources support topical cosmetic use; irritation and sun-sensitivity considerations relate more to formula context than to pregnancy-specific risk.
Sources: CIR: Safety Assessment of Alpha Hydroxy Acids as Used in Cosmetics; CIR: PCA and Its Salts as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Urea
No known risks
A naturally occurring component of skin moisturizing factors, used in cosmetics as a humectant and at higher concentrations as a keratolytic. Ordinary cosmetic use does not identify a pregnancy-specific concern. Higher-strength products may sting or irritate damaged skin. Urea itself is distinct from formaldehyde-releasing preservatives such as imidazolidinyl urea and diazolidinyl urea.
Sources: CIR ingredient record: Urea https://cir-safety.org/ingredient/urea; EU CosIng cosmetic ingredient inventory: Urea
Sodium Chloride
No known risks
Sodium chloride is used to adjust viscosity and texture in formulations; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks.
Sources: CIR; EU/UK Cosmetics Regulation
Citric Acid
No known risks
pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Betaine
No known risks
Betaine is a humectant/osmolyte used to support hydration and reduce irritation potential in formulas; it is considered low concern with no known pregnancy or breastfeeding risks in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Allantoin
No known risks
Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Fructose
No known risks
This sugar or sugar alcohol is used as a humectant and skin-conditioning ingredient. Cosmetic Ingredient Review assessments support these saccharides in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.
Sources: CIR: Safety Assessment of Monosaccharides Disaccharides and Related Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-monosaccharides-disaccharides-and-related-ingredients-used-cosmeti
Maltose
No known risks
A sugar or carbohydrate-derived conditioner used for hydration and texture. No reproductive or developmental concern was identified for normal topical exposure.
Sources: European Commission CosIng; biochemical and cosmetic literature on saccharides.
Trehalose
No known risks
Sugar-derived humectant used to help bind water and improve skin feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.
Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Glucose
No known risks
Simple sugar used as a humectant and skin-conditioning support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.
Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Pentylene Glycol
No known risks
Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Synthetic Beeswax
No known risks
A manufactured wax used for structure and emolliency without relying on natural bee-derived material. Cosmetic safety reviewers reaffirmed synthetic beeswax as safe in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.
Sources: CIR: Safety Assessment of Fossil and Synthetic Waxes https://www.cir-safety.org/sites/default/files/Fossils%20%26%20Synthetic%20Waxes_0.pdf
Polyacrylate Crosspolymer-6
No known risks
Large polymer thickener and stabilizer used in gels, serums and creams. Systemic exposure from topical cosmetic use is expected to be low, with no pregnancy- or breastfeeding-specific concern identified in reviewed cosmetic references.
Sources: CIR cosmetic ingredient safety references for acrylates/polyacrylate crosspolymers; EU CosIng / cosmetics regulatory inventory
Dimethiconol
No known risks
A high-molecular-weight silicone polymer used for film forming, smoothing and skin or hair conditioning. The Cosmetic Ingredient Review concluded that Dimethiconol and its assessed derivatives are safe in current cosmetic use. Its polymeric nature limits skin penetration, and available evidence does not identify a pregnancy- or breastfeeding-specific concern for normal topical exposure.
Sources: CIR: Safety Assessment of Dimethiconol and its Esters and Reaction Products; International Journal of Toxicology 36(Suppl. 3):31-50 (2017) https://cir-safety.org/ingredient/dimethiconol
Ethylhexylglycerin
No known risks
Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Caprylyl Glycol
No known risks
Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Sodium Hydroxide
No known risks
pH adjuster used in very small quantities to balance formulations. Not associated with pregnancy-specific concerns.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Full recorded ingredient list
Water, Glycerin, Dimethicone, Cetearyl Olivate, Sorbitan Olivate, Sodium Hyaluronate, Serine, Glycine, Alanine, Threonine, Arginine, Proline, Lysine Hcl, Glutamic Acid, Sodium PCA, PCA, Sodium Lactate, Urea, Sodium Chloride, Citric Acid, Betaine, Allantoin, Fructose, Maltose, Trehalose, Glucose, Pentylene Glycol, Synthetic Beeswax, Polyacrylate Crosspolymer-6, Dimethicone Crosspolymer, Dimethiconol, Ethylhexylglycerin, Caprylyl Glycol, Sodium Hydroxide
Ingredient ratings refreshed 1 October 2026. Formulas vary by market and can change. Always compare with your packaging.
Questions about this assessment
Why does Neutrogena Hydro Boost Gel Cream have a Low risk rating?
The recorded formula includes 2 ingredient entries with risk flags: Dimethicone (Low risk), Dimethicone Crosspolymer (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail. The product score is a stored assessment, not a clinical safety guarantee.
Has every ingredient in Neutrogena Hydro Boost Gel Cream been assessed?
34 of 34 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
Does this assessment apply to my Neutrogena Hydro Boost Gel Cream?
Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.
Does this pregnancy assessment also establish breastfeeding suitability?
No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.
