Madagascar Centella Ampoule Foam

A cleansing and foam-supporting surfactant made from coconut-derived fatty chains. Cosmetic safety reviewers concluded that alkyl betaines, including coco-betaine, are safe in current practices when formulated to be non-irritating. Surfactant-containing products may still sting eyes or irritated skin.

Sources: CIR: Quick Reference Table conclusion for Coco-Betaine and alkyl betaines https://www.cir-safety.org/sites/default/files/sq-fix_2.pdf

Botanical skin-conditioning ingredient used in soothing and barrier-support formulas. Reviewed cosmetic safety sources support current cosmetic use when formulated to be non-sensitising, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

Sources: CIR: Safety Assessment of Centella asiatica-derived Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

An amino-acid-derived surfactant or conditioning ingredient. Cosmetic safety reviewers concluded that amino acid alkyl amides are safe in current cosmetic practices when formulated to be non-irritating. Manufacturing and formulation should control nitrosamine formation where relevant.

Sources: CIR: Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-amino-acid-alkyl-amides-used-cosmetics-0

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

A fatty-acid salt used mainly as a soap, cleanser, emulsifier or formula structurant. Cosmetic safety reviewers concluded that sodium palmate and potassium cocoate are safe in current cosmetic practices, with non-irritating formulation conditions where specified.

Sources: CIR: Sodium Palmate conclusion, IJT 36(Suppl. 3), 2017; Potassium Cocoate conclusions, IJT 30(Suppl. 1), 2011 and IJT 34(Suppl. 2), 2015; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

A functional cosmetic ingredient used for preservation support, pH control, chelation, solvent action or formula stability. Concentrated material may irritate skin or eyes, but no pregnancy-specific reproductive or developmental hazard was identified for normal use in a compliant finished cosmetic.

Sources: European Commission CosIng ingredient inventory and applicable cosmetic restrictions; relevant CIR ingredient and functional-family safety assessments.

A numbered cationic polymer used for hair conditioning, antistatic effects, film formation or formula texture. The Polyquaternium number identifies a distinct polymer, so evidence from one number is not treated as proof for every other number. For this ingredient, no pregnancy, reproductive or breastfeeding hazard signal was identified in the cosmetic-use and substance information reviewed. Its polymeric size makes meaningful absorption through intact skin unlikely; local irritation and control of residual monomers remain formulation-quality considerations.

Sources: European Commission CosIng ingredient inventory; CIR safety assessments and December 2025 Quick Reference Table for structurally and functionally related polyquaternium cosmetic polymers https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf; publicly available supplier safety data and ECHA substance information where available for the named polymer. No ingredient-specific pregnancy studies were identified.

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Sodium chloride is used to adjust viscosity and texture in formulations; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks.

Sources: CIR; EU/UK Cosmetics Regulation

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Starch-derived polysaccharide used as a binder, film former and texture support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for polysaccharides/starch-derived ingredients; EU CosIng / cosmetics regulatory inventory

A fruit, seed or food-plant extract used for skin conditioning and antioxidant support. No pregnancy-specific signal was identified for the low topical exposure expected from a finished cosmetic. Direct pregnancy studies are generally unavailable, and botanical allergy remains possible.

Sources: European Commission CosIng ingredient inventory; CIR botanical safety framework and relevant fruit-derived ingredient assessments; peer-reviewed cosmetic and phytochemical literature for the named plants.

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

A small organic acid, salt or ester used as a solvent, pH adjuster or formula aid. Cosmetic safety reviewers concluded that acetic acid and the assessed related simple alcohols and esters are safe in current practices.

Sources: CIR: Acetic Acid and related simple alcohols and esters, IJT 31(Suppl. 1), 2012; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

An alkaline mineral salt used for deodorising, buffering and mild abrasion. Cosmetic safety reviewers concluded that sodium bicarbonate is safe in current practices. It can irritate sensitive or freshly shaved skin in some formulas.

Sources: CIR: Sodium Bicarbonate conclusion, 2025; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

An ivy-gourd fruit extract used for skin conditioning and antioxidant support. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant ingredient-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

A plant-part extract used for skin conditioning, soothing, fragrance or antioxidant support. No pregnancy-specific systemic signal was identified for normal topical cosmetic exposure. This assessment does not extend to essential oils, oral herbal products or medicinal doses, and botanical sensitivity remains possible.

Sources: European Commission CosIng ingredient inventory; CIR botanical safety framework and relevant plant-derived ingredient assessments; peer-reviewed cosmetic-use literature.