SKIN1004 Madagascar Centella Poremizing Fresh Ampoule

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Botanical skin-conditioning ingredient used in soothing and hydrating formulas. Reviewed cosmetic safety sources support current cosmetic use provided anthraquinone levels do not exceed the limits addressed in the safety assessment; no pregnancy- or breastfeeding-specific topical concern was identified in the material reviewed.

An ethoxylated glycerin humectant used to retain moisture and improve product texture. The Cosmetic Ingredient Review assessed glycerin ethoxylates including Glycereth-26 for current cosmetic use; available evidence does not identify a pregnancy- or breastfeeding-specific concern from normal topical exposure.

Hydroxyacetophenone is used as an antioxidant and preservative-support ingredient; it is generally considered low concern in topical cosmetic use with no known pregnancy or breastfeeding risks at typical concentrations.

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.

pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

A high-molecular-weight polymer used to thicken and stabilise formulas. Cosmetic safety reviewers concluded that acryloyldimethyltaurate polymers are safe in current cosmetic practices. Absorption of the finished polymer is expected to be limited, with residual monomers controlled during manufacture.

Microbial polysaccharide used for film forming, soothing, and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

High-water-binding humectant used to support hydration at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Humectant and skin-conditioning ingredient in the hyaluronate family. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Cellulose-derived thickener used to build viscosity and improve texture. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

A German chamomile flower extract used for skin conditioning and soothing. Cosmetic safety reviewers concluded that Chamomilla recutita flower-derived ingredients are safe in current cosmetic use when formulated to be non-sensitizing. Chamomile can cause contact allergy in susceptible people, particularly those sensitive to plants in the Asteraceae family, but no pregnancy-specific concern is identified for normal topical cosmetic exposure.

tripeptide-3 is an amino acid, peptide, protein-related or glycosaminoglycan cosmetic conditioning ingredient. Expected systemic exposure from normal topical use is low, and relevant cosmetic-family assessments did not identify a pregnancy-specific concern. Manufacturing quality and residual allergenic proteins remain relevant where applicable.

Synthetic peptide used as a skin-conditioning ingredient. Reviewed cosmetic safety sources do not indicate a known pregnancy- or breastfeeding-specific concern in normal topical cosmetic use. The available cosmetic safety assessment concluded this ingredient is safe in cosmetics at concentrations up to 0.005%; safety above that concentration was not established in the reviewed report.

Synthetic acetylated peptide used in topical cosmetic anti-aging formulas, commonly as an expression-line peptide. Available cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Copper-binding carrier peptide also known as GHK-Cu, used topically in cosmetic skin-renewal, anti-aging, barrier-support and hair/scalp products. Reviewed literature describes topical cosmetic use and does not identify a pregnancy- or breastfeeding-specific risk signal for normal topical use. This assessment does not apply to injectable copper peptides or oral peptide/copper supplementation.

Synthetic palmitoylated signal peptide used in topical anti-aging cosmetics. It is one of the better-studied cosmetic peptides, with reviewed topical literature describing controlled cosmetic studies and no pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Synthetic signal peptide used in topical cosmetic anti-aging and skin-conditioning formulas. Reviewed topical peptide literature describes palmitoyl tetrapeptide-7 as a cosmetic peptide with anti-inflammatory and extracellular-matrix support activity in topical formulations. No pregnancy- or breastfeeding-specific risk signal was identified for normal topical cosmetic use.

Synthetic peptide used as a skin-conditioning ingredient. Reviewed cosmetic safety sources indicate no known pregnancy- or breastfeeding-specific concern in normal topical cosmetic use. Available cosmetic safety assessments conclude this ingredient is safe in the present practices of use and concentration described for cosmetics.

Short synthetic peptide used as a skin-conditioning cosmetic ingredient. Cosmetic safety review sources for tripeptide-1 and related derivatives do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.