SKIN1004 Madagascar Centella Soothing Cream by SKIN1004
SKIN1004

SKIN1004 Madagascar Centella Soothing Cream

General Moisturizersmoisturisers

Safety score

Pregnancy-focused assessment

Low Risk75/100
Higher concernLower concern

One or more ingredients have a low-risk flag in MamaSkin's current assessment. Review the notes and your own circumstances.

Formula and assessment check

Ingredient safety review updated 18 June 2026. Product formulas can change, so compare the ingredients shown here with the packaging you have.

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Ingredient breakdown

See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.

34

No known risks

4

Low risk

0

Medium risk

0

High risk

Ingredients

Ingredients with a higher risk flag appear first, followed by the rest of the formula.

Tranexamic Acid

Low Risk

Synthetic lysine analogue used topically for melasma and hyperpigmentation; inhibits plasmin activity and downstream melanogenesis. Topical formulations (≈2–5%) show low systemic absorption and no reported teratogenic effects, but pregnancy-specific data remain limited. Many sources regard it as pregnancy-safe or acceptable, while some advise cautious use or deferral until after pregnancy due to limited evidence.

Sources: PubMed: Topical tranexamic acid dermatology literature https://pubmed.ncbi.nlm.nih.gov/?term=topical+tranexamic+acid+melasma+safety

Cyclomethicone

Low Risk

A generic name for volatile cyclic siloxane mixtures used for slip and quick-drying texture. Cosmetic reviews have supported cyclomethicone use, but the generic label may encompass D4, D5 or related cyclic siloxanes with different reproductive, impurity and spray-route evidence. MamaSkin classifies the generic ingredient as low risk because its exact composition is not disclosed.

Sources: CIR: Cyclomethicone https://cir-safety.org/ingredient/cyclomethicone; European Commission SCCS: Opinion on Cyclopentasiloxane (D5) in Cosmetic Products https://health.ec.europa.eu/publications/decamethylcyclopentasiloxane-cyclopentasiloxane-d5-cosmetic-products_en; European Commission SCCP: Cyclomethicone D4 request https://ec.europa.eu/health/ph_risk/committees/04_sccp/docs/sccp_q_188.pdf

C30-45 Alkyl Cetearyl Dimethicone Crosspolymer

Low Risk

Silicone derivative with negligible systemic absorption in topical cosmetic use; treated as low risk in pregnancy and breastfeeding.

Sources: CIR: Safety Assessment of Dimethicone Crosspolymers as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-dimethicone-crosspolymers-used-cosmetics

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Dipotassium Glycyrrhizate

Low Risk

A purified glycyrrhizic-acid salt used as a soothing and skin-conditioning ingredient. Cosmetic safety reviewers concluded that dipotassium glycyrrhizate is safe in current cosmetic use and noted poor dermal absorption. MamaSkin nevertheless applies a cautious low-risk classification for consistency with the existing licorice family because high oral glycyrrhizin exposure has pregnancy-related concerns; this is not a topical contraindication.

Sources: CIR: Safety Assessment of Glycyrrhizic Acid and Derivatives https://cir-reports.cir-safety.org/view-attachment/?id=49a63435-8e74-ec11-8943-0022482f06a6

Centella Asiatica Extract (72%)

No Known Risks

Botanical skin-conditioning ingredient used in soothing and barrier-support formulas. Reviewed cosmetic safety sources support current cosmetic use when formulated to be non-sensitising, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

Sources: CIR: Safety Assessment of Centella asiatica-derived Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Glycerin

No Known Risks

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Propanediol

No Known Risks

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Dipropylene Glycol

No Known Risks

Dipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Water

No Known Risks

1,2-Hexanediol

No Known Risks

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

Trehalose

No Known Risks

Sugar-derived humectant used to help bind water and improve skin feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Caprylyl Methicone

No Known Risks

Volatile/low-residue silicone emollient used to improve spreadability and sensory feel. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Amended Safety Assessment of Dimethicone, Methicone, and Substituted-Methicone Polymers as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

C12-14 Pareth-12

No Known Risks

An ethoxylated fatty alcohol used as an emulsifier, surfactant or solubiliser. Cosmetic safety reviewers concluded that these named alkyl PEG ethers are safe in current practices when formulated to be non-irritating. Manufacturing controls should limit residual ethylene oxide and 1,4-dioxane.

Sources: CIR: Alkyl PEG/PPG Ethers conclusions, including C11-15 Pareth-7, C12-14 Pareth-12, Octyldodeceth-16 and Ceteareth-12; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Carbomer

No Known Risks

Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Tromethamine

No Known Risks

pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Tromethamine as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Ammonium Acryloyldimethyltaurate/VP Copolymer

No Known Risks

Polymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Xanthan Gum

No Known Risks

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Sources: European cosmetics regulatory framework

Mentha Piperita (Peppermint) Leaf Extract

No Known Risks

Mentha Piperita (Peppermint) Leaf Extract is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not a concentrated essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

Sources: CIR ingredient-specific and botanical-family safety assessments; CIR Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng

Zingiber Officinale (Ginger) Root Extract

No Known Risks

zingiber officinale (ginger) root extract is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not an essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

Sources: CIR ingredient-specific and botanical-family safety assessments; CIR Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf; European Commission CosIng

Butylene Glycol

No Known Risks

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Ethylhexylglycerin

No Known Risks

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Coptis Chinensis Root Extract

No Known Risks

Theobroma Cacao (Cocoa) Extract

No Known Risks

Dextrin

No Known Risks

Starch-derived polysaccharide used as a binder, film former and texture support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for polysaccharides/starch-derived ingredients; EU CosIng / cosmetics regulatory inventory

Leuconostoc/Radish Root Ferment Filtrate

No Known Risks

A filtered radish-root fermentation product used mainly for skin conditioning and formulation support. Cosmetic safety reviewers concluded that the reviewed radish-root-derived ingredients, including Leuconostoc/Radish Root Ferment Filtrate, are safe in current cosmetic use when formulated to be non-irritating. Testing at cosmetic-relevant concentrations did not identify irritation, sensitization, phototoxicity or ocular irritation concerns.

Sources: CIR: Safety Assessment of Radish Root-Derived Ingredients https://cir-safety.org/sites/default/files/FR_RadishRoot_062022.pdf

Biosaccharide Gum-1

No Known Risks

Microbial polysaccharide used for film forming, soothing, and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Disodium EDTA

No Known Risks

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Sodium Hyaluronate

No Known Risks

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Beta-Glucan

No Known Risks

Film-forming polysaccharide used for soothing and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Ceramide EOP

No Known Risks

Skin-identical barrier lipid used to support barrier structure and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Ceramides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Ceramide NS

No Known Risks

A skin-identical barrier lipid used for skin and hair conditioning. Cosmetic safety reviewers concluded that Ceramide NS is safe in current cosmetic use, noting limited skin absorption and reassuring toxicity data. Cosmetic-grade material should not be sourced from bovine central nervous system tissue.

Sources: CIR: Safety Assessment of Ceramides https://cir-safety.org/sites/default/files/cerami122014tent.pdf

Ceramide NP

No Known Risks

Skin-identical barrier lipid used to support the stratum corneum and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Ceramides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Ceramide AP

No Known Risks

Skin-identical barrier lipid used to support barrier function and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Ceramides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Phytosphingosine

No Known Risks

Skin-conditioning lipid used in barrier-support formulas, commonly alongside ceramides and cholesterol. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for sphingolipids/skin-conditioning lipids; EU CosIng / cosmetics regulatory inventory

Hydrogenated Lecithin

No Known Risks

Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US)

Cetearyl Alcohol

No Known Risks

Fatty alcohol used as an emollient and thickener. Not the same as drying alcohols and not associated with pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Stearic Acid

No Known Risks

Stearic acid is a fatty acid used to stabilise emulsions and improve texture; it is considered low concern in topical cosmetics with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Cholesterol

No Known Risks

Skin-conditioning lipid used in barrier-support formulas, often alongside ceramides and fatty acids. Normal topical cosmetic use has no known pregnancy- or breastfeeding-specific concern identified in reviewed cosmetic references.

Sources: CIR cosmetic ingredient safety references for cholesterol and related sterols; EU CosIng / cosmetics regulatory inventory

Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.

How to use this assessment

The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.

MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.

Read the full methodology