Safety score
Pregnancy-focused assessment
One or more ingredients have a low-risk flag in MamaSkin's current assessment. Review the notes and your own circumstances.
Formula and assessment check
Ingredient safety review updated 7 January 2026. Product formulas can change, so compare the ingredients shown here with the packaging you have.
Report a formula mismatchSee how the listed formula falls across MamaSkin's pregnancy-focused risk bands.
25
No known risks
1
Low risk
0
Medium risk
0
High risk
Ingredients with a higher risk flag appear first, followed by the rest of the formula.
Synthetic lysine analogue used topically for melasma and hyperpigmentation; inhibits plasmin activity and downstream melanogenesis. Topical formulations (≈2–5%) show low systemic absorption and no reported teratogenic effects, but pregnancy-specific data remain limited. Many sources regard it as pregnancy-safe or acceptable, while some advise cautious use or deferral until after pregnancy due to limited evidence.
Sources: PubMed, U.S. National Library of Medicine (NLM)
1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.
Sources: CIR; EU/UK Cosmetics Regulation
A stable ether derivative of vitamin C used as an antioxidant and brightening ingredient. Pregnancy-specific topical studies are limited, but no pregnancy-specific contraindication was identified in the reviewed literature. Published case reports describe allergic contact dermatitis, so local sensitivity remains possible and this classification should not be read as proof that irritation cannot occur.
Sources: CIR: Safety Assessment of Ethers of Ascorbic Acid https://www.cir-safety.org/sites/default/files/ethers_of_ascorbate.pdf; PubMed: 3-O-ethyl-L-ascorbic acid topical delivery https://pubmed.ncbi.nlm.nih.gov/31517290/; PubMed: allergic contact dermatitis case report https://pubmed.ncbi.nlm.nih.gov/24846587/
Polymer thickener and stabiliser used in creams and sunscreens. Low systemic exposure expected.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Sugar-derived humectant used to support hydration, often as part of saccharide blends. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Saccharide Humectants / Saccharide Isomerate, etc.; EU CosIng / cosmetics regulatory inventory
Amino acid used as a humectant, skin-conditioning agent, and pH-adjusting support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of α-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Betaine is a humectant/osmolyte used to support hydration and reduce irritation potential in formulas; it is considered low concern with no known pregnancy or breastfeeding risks in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Botanical skin-conditioning ingredient used in soothing and barrier-support formulas. Reviewed cosmetic safety sources support current cosmetic use when formulated to be non-sensitising, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Centella asiatica-derived Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Simple sugar used as a humectant and skin-conditioning support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.
Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.
Sources: Cosmetic Ingredient Review (US)
Cellulose-derived thickener used to build viscosity and improve texture. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR Quick Reference Table / ingredient status (Hydroxyethylcellulose, Final Report 03/2009); EU CosIng / cosmetics regulatory inventory
Ferment-derived skin-conditioning ingredient used in microbiome-support and soothing formulas. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Lactobacillus Ferment Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
A triterpene glycoside associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical madecassoside is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but noted that madecassoside and related triterpenes may contribute to sensitisation, so products should be formulated to avoid sensitising concentrations. No pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
This sugar or sugar alcohol is used as a humectant and skin-conditioning ingredient. Cosmetic Ingredient Review assessments support these saccharides in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.
Sources: CIR: Safety Assessment of Monosaccharides Disaccharides and Related Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-monosaccharides-disaccharides-and-related-ingredients-used-cosmeti
This cellulose or modified-cellulose polymer is used as a thickener, film former or stabilizer. Cosmetic Ingredient Review data indicate that cellulose polymers do not appreciably penetrate skin and are safe in current cosmetic use, with at most minimal irritation reported.
Sources: CIR: Amended Safety Assessment of Cellulose and Related Polymers as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=2e65c18f-8c74-ec11-8943-0022482f06a6
Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.
Sources: European cosmetics regulatory framework
Sugar alcohol humectant used to help maintain hydration and improve skin feel. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Mannitol, Sorbitol, and Xylitol as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
A sugar-derived humectant commonly used with xylitol and anhydroxylitol to support skin hydration. Exact pregnancy-specific topical data are limited. Cosmetic safety assessments of the related saccharide mixture and xylitol did not identify a reproductive or pregnancy-specific concern at cosmetic exposure; available data primarily support local tolerance rather than proving pregnancy safety. No topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Saccharide Isomerate and Related Saccharides https://cir-safety.org/supplementaldoc/safety-assessment-anhydrogalactose-anhydroglucitol-anhydroxylitol-arabinose-psicose-; CIR: Safety Assessment of Mannitol, Sorbitol, and Xylitol https://www.cir-safety.org/sites/default/files/xylito122019FR.pdf
Corn starch, a plant-derived polysaccharide used to absorb moisture, reduce greasiness and improve texture. Cosmetic safety reviewers concluded that ingredients derived from Zea mays, including corn starch, are safe in current cosmetic use. No pregnancy-specific concern is identified for normal topical exposure; avoid deliberately inhaling loose powder.
Sources: CIR ingredient review: Zea mays (Corn) Starch https://www.cir-safety.org/ingredient/zea-mays-corn-starch
Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.
The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.
MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.
