2 minutes

Is Niacinamide Safe During Pregnancy?

Why this barrier-loving vitamin B3 derivative is considered pregnancy-safe, how to patch test it, and which formulas are worth adding to your routine.

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Is Niacinamide Safe During Pregnancy?

Is Niacinamide Safe During Pregnancy?

Niacinamide (vitamin B3) is one of the easiest ingredients to keep in rotation when you are expecting. It is not a retinoid, it is not an exfoliating acid, and dermatology bodies consider it safe for use during pregnancy and breastfeeding. That is why MamaSkin rarely flags it unless it is surrounded by more questionable companions.

What the science and doctors say

  • Niacinamide is a water-soluble vitamin that helps barrier repair, reduces transepidermal water loss, and calms redness.
  • No human studies have shown teratogenic risk when used topically at standard 2-10% levels.
  • The NHS and the American College of Obstetricians and Gynecologists both list vitamin B3 as compatible with pregnancy, although you should still patch test if you have a history of sensitivity.

How to work it into a pregnancy-safe routine

  1. Use it after cleansing on damp skin so it penetrates evenly without tingling.
  2. Layer your moisturiser immediately afterwards to lock hydration in.
  3. Pair with azelaic acid or gentle AHAs, never with prescription vitamin A. Niacinamide actually reduces the irritation some exfoliants can cause.
  4. Stay consistent. Pigmentation, pores, and texture benefits show up after 4-6 weeks of daily use.

Product formulas we actually finished

  1. The Ordinary Niacinamide 10% + Zinc 1% – lightweight, fragrance-free, and easy to spot treat.
  2. The INKEY List Niacinamide Serum – 10% niacinamide paired with 1% hyaluronic acid to prevent dryness.
  3. Glow Recipe Watermelon Glow Niacinamide Dew Drops – doubles as a highlight under SPF, ideal if you miss your glow but do not want shimmer.

Remember to scan every serum with MamaSkin before you apply it. Some brands sneak niacinamide into blends that also contain retinoids or high-dose BHAs, and the app catches those combinations instantly.

When to pause or switch

  • If you experience flushing or your skin barrier feels tight, reduce use to every other night and add a richer moisturiser.
  • Stop and speak to your midwife if you develop contact dermatitis or if niacinamide is packaged with prescription-strength actives.
  • Save your notes and scan history in MamaSkin so you can spot patterns trimester by trimester.

Make MamaSkin part of the habit

Open your routine tracker in the app, log when you add niacinamide, and set a reminder to review how your skin looks after four weeks. Mia, our AI helper, translates the ingredient list for you so you know exactly why a serum was cleared or cautioned.

Download MamaSkin (iOS & Android): App Store | Google Play

Need a product checked?

Scan the label inside the MamaSkin app to get instant ingredient guidance.

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Published 3 December 2025