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A diester used as an emollient, solvent and plasticizer. After reviewing additional dermal, reproductive, developmental and genotoxicity data, cosmetic safety reviewers concluded that dibutyl adipate is safe in current cosmetic use and concentration. No pregnancy-specific concern is identified for normal topical cosmetic exposure.

UV filter used in sunscreens and day products to help absorb UVB radiation. Reviewed cosmetic safety and regulatory sources support current cosmetic use within applicable concentration limits, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Organic UVA/UVB filter used in sunscreens, also known as Mexoryl XL. Cosmetic safety and regulatory sources support use within applicable concentration limits, with no pregnancy- or breastfeeding-specific topical concern identified in the sources reviewed.

A polyglycerin fatty-acid ester used as an emulsifier, dispersant or emollient. Cosmetic safety reviewers concluded that the assessed family of 274 polyglyceryl fatty acid esters is safe in current practices when formulated to be non-irritating. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Organic UVA filter used in sunscreens, also known as Ecamsule or Mexoryl SX. Cosmetic safety and regulatory sources support use within applicable concentration limits, with no pregnancy- or breastfeeding-specific topical concern identified in the sources reviewed.

Modern UVA filter (often called Uvinul A+ or DHHB). Regulatory assessments have repeatedly evaluated this filter as safe in cosmetic products at concentrations up to 10%. The most recent SCCS advice focuses on controlling a manufacturing impurity (DnHexP) rather than on new toxicity of DHHB itself. Human biomonitoring data indicate low systemic exposure from normal sunscreen use, and current reviews do not identify specific reproductive or developmental toxicity signals at approved concentrations.

A silicone resin used as a film former, texture enhancer and opacifying ingredient in makeup, sunscreen and skin care. The Cosmetic Ingredient Review concluded that polysilsesquioxanes including Polymethylsilsesquioxane are safe in current cosmetic use. Available evidence does not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic exposure.

pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

Emulsifier and emollient used to stabilise creams and lotions. Not associated with pregnancy-specific concerns at cosmetic exposure.

Mineral absorbent and texture aid used to mattify and improve slip. Reviewed cosmetic safety sources support normal topical cosmetic use; this assessment does not cover deliberate inhalation of loose powder.

Volatile/low-residue silicone emollient used to improve spreadability and sensory feel. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

An oat kernel extract used for skin conditioning and soothing. Cosmetic safety reviewers concluded that Avena sativa kernel extract and most assessed oat-derived ingredients are safe in current practices of use and concentration when formulated to be non-sensitising and manufactured with appropriate impurity controls. Oat allergy or contact sensitivity can occur in susceptible people, but no pregnancy-specific concern was identified for normal topical cosmetic exposure.

Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.

This plant-derived fatty oil or butter is used as an emollient and skin-conditioning ingredient. The Cosmetic Ingredient Review concluded that assessed plant-derived fatty acid oils are safe as used in cosmetics; individual plant allergy and ingredient purity remain practical considerations.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Modern broad-spectrum UV filter (often known as Tinosorb S). It has a high molecular weight and is formulated to remain mainly in the outer skin layers, with very low systemic absorption at cosmetic use levels. EU regulatory assessments and independent risk–benefit reviews have evaluated this filter as safe up to 10% in sunscreens, with no specific reproductive or developmental toxicity signals identified in animals or humans at permitted concentrations.

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

An alkyl phosphate surfactant and emulsifier used to stabilise creams, sunscreens and makeup. Cosmetic safety reviewers concluded that the assessed alkyl phosphates, including potassium cetyl phosphate, are safe in current practices of use and concentration when formulated to be non-irritating. Dermal penetration is expected to be limited, and no pregnancy-specific concern is identified for normal topical cosmetic exposure.

Solvent and humectant used to improve texture and ingredient delivery in topical cosmetic formulas. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.

Polymer thickener and stabiliser used in creams and sunscreens. Low systemic exposure expected.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

A large phosphorylcholine-containing conditioning polymer. Cosmetic safety reviewers concluded that acryloyloxyethyl phosphorylcholine polymers, including polyquaternium-51, are safe in current practices. Available testing did not indicate sensitisation, and dermal absorption of the finished polymer is expected to be limited.

Film-forming polysaccharide used for soothing and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Microbial polysaccharide used for film forming, soothing, and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

A naturally occurring sugar alcohol used for conditioning and hydration. Cosmetic safety reviewers concluded that inositol is safe in current practices of use and concentration. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Skin-identical barrier lipid used to support the stratum corneum and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Skin-conditioning lipid used in barrier-support formulas, commonly alongside ceramides and cholesterol. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.