
Biodance

Toners
Some ingredients carry a low-risk flag. Read the formulation context before deciding.
25 of 25 ingredients rated
MamaSkin rates the recorded formula for Biodance Collagen Gel Toner Pads as Low risk (79/100). Review the ingredient context and any manual-review explanation before deciding.
Contains recombinant human growth-factor-style peptide(s): sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1. These are not currently treated as known pregnancy-restricted ingredients in normal topical cosmetic use, but pregnancy-specific data are limited and they are biologically framed signaling peptides/proteins. MamaSkin scores them conservatively as low risk. This applies to topical cosmetic products only, not injectable growth-factor treatments, microneedling serums, wound use, or oral supplements.
25 of 25 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
How we assess productsThe recorded formula, with evidence behind each rating. Unmatched ingredients are marked Not assessed in grey.
sh-Polypeptide-22 is a recombinant human TGF-beta-1-style signalling protein used in topical skin-conditioning formulas. Intact-skin systemic absorption is expected to be limited, but pregnancy and breastfeeding studies of cosmetic use are lacking. MamaSkin scores it conservatively as Low Risk, consistent with other recombinant sh-polypeptides. This assessment applies only to ordinary intact-skin cosmetic use.
Sources: KCIA INCI identity https://kcia.or.kr/cid/search/ingd_view.php?no=6635; systematic review of topical growth-factor preparations https://pubmed.ncbi.nlm.nih.gov/37222303/; review of cosmetic growth factors and peptides https://pubmed.ncbi.nlm.nih.gov/27877059/
Recombinant human oligopeptide cosmetic ingredient used in topical growth-factor-style formulas, commonly associated with EGF-style skin-conditioning claims. Normal topical cosmetic use is not currently treated as a known pregnancy-restricted concern, and these larger signaling peptides are expected to have limited intact-skin penetration. Pregnancy- and breastfeeding-specific cosmetic data are limited, so MamaSkin scores this conservatively as low risk rather than no known risks. This assessment applies to topical cosmetic products only, not injectable growth-factor treatments, microneedling serums, wound use, or oral supplements.
Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. https://doi.org/10.3390/cosmetics4020016; Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth factors: a pilot study. J Cosmet Laser Ther. 2003;5(1):25-34; dermatology reviews on topical growth factors and skin rejuvenation; EU CosIng / INCI cosmetic ingredient references.
Recombinant human polypeptide cosmetic ingredient used in topical growth-factor-style skin-conditioning formulas. Normal topical cosmetic use is not currently treated as a known pregnancy-restricted concern, and large peptide/protein ingredients are expected to have limited intact-skin penetration. Pregnancy- and breastfeeding-specific cosmetic data are limited, so MamaSkin scores this conservatively as low risk rather than no known risks. This assessment applies to topical cosmetic products only, not injectable growth-factor treatments, microneedling serums, wound use, or oral supplements.
Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. https://doi.org/10.3390/cosmetics4020016; Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth factors: a pilot study. J Cosmet Laser Ther. 2003;5(1):25-34; dermatology reviews on topical growth factors and skin rejuvenation; EU CosIng / INCI cosmetic ingredient references.
Recombinant human oligopeptide cosmetic ingredient used in topical growth-factor-style skin-conditioning formulas. Normal topical cosmetic use is not currently treated as a known pregnancy-restricted concern, but pregnancy- and breastfeeding-specific cosmetic data are limited. Because this ingredient is biologically framed as a signaling peptide rather than a simple cosmetic conditioning peptide, MamaSkin scores it conservatively as low risk. This assessment applies to topical cosmetic products only, not injectable growth-factor treatments, microneedling serums, wound use, or oral supplements.
Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. https://doi.org/10.3390/cosmetics4020016; Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth factors: a pilot study. J Cosmet Laser Ther. 2003;5(1):25-34; dermatology reviews on topical growth factors and skin rejuvenation; EU CosIng / INCI cosmetic ingredient references.
sh-Polypeptide-3 is a recombinant human keratinocyte-growth-factor-style protein used in topical conditioning formulas. Intact-skin absorption is expected to be limited, but pregnancy and breastfeeding studies are lacking. MamaSkin scores it conservatively as Low Risk, consistent with other recombinant sh-polypeptides.
Sources: KCIA INCI record for the rice-expressed form https://kcia.or.kr/cid/search/ingd_view.php?no=9902; growth-factor delivery review https://pubmed.ncbi.nlm.nih.gov/33354795/
Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en
No pregnancy-specific harm has been identified for ordinary, correctly formulated topical cosmetic use of collagen water. This is a bounded protein/peptide/ferment assessment; direct pregnancy studies of the exact material are limited and oral, medicinal, damaged-skin or aerosol exposure is not included.
Sources: https://www.cir-safety.org/sites/default/files/tsupep092017final.pdf
Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.
Sources: CIR; EU/UK Cosmetics Regulation
Polyglycerin fatty-acid ester used as an emulsifier and solubilizer. Reviewed cosmetic safety references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.
Sources: CIR cosmetic ingredient safety references for polyglyceryl fatty acid esters; EU CosIng / cosmetics regulatory inventory
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Amino acid used as a humectant, skin-conditioning agent, and pH-adjusting support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of α-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.
Sources: European cosmetics regulatory framework
Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Polymer used for texture and absorbency. Large-molecule ingredient with low systemic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
A vitamin B ingredient or derivative used for skin or hair conditioning. These vitamins are normal nutrients and no pregnancy-specific concern was identified for the small topical exposure expected from a finished cosmetic. This assessment does not replace guidance about oral supplements or therapeutic doses.
Sources: NIH Office of Dietary Supplements vitamin fact sheets https://ods.od.nih.gov/factsheets/list-all/; CIR: Panthenol, Pantothenic Acid and Derivatives safety assessment https://www.cir-safety.org/supplementaldoc/safety-assessment-panthenol-pantothenic-acid-and-derivatives-used-cosmetics-1
Synthetic signal peptide used in topical cosmetic anti-aging and skin-conditioning formulas. Reviewed cosmetic peptide literature lists palmitoyl tripeptide-5 among topically used matricin-style peptides. No pregnancy- or breastfeeding-specific risk signal was identified for normal topical cosmetic use.
Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. doi:10.3390/cosmetics4020016; EU CosIng / INCI cosmetic ingredient references.
Humectant and skin-conditioning ingredient in the hyaluronate family. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
An animal-derived protein, peptide or secretion filtrate used for hydration and skin conditioning. These large components are expected to have low systemic absorption through intact skin. No pregnancy-specific hazard signal was identified for normal topical cosmetic use. Cosmetic-grade materials should be processed to control microorganisms, infectious agents and source-derived impurities, and protein allergy remains possible.
Sources: CIR: Safety Assessment of Skin and Connective Tissue-Derived Proteins and Peptides https://www.cir-safety.org/sites/default/files/tsupep092017final.pdf; European Commission CosIng ingredient inventory; peer-reviewed cosmetic literature on snail secretion filtrate.
A structural protein or hydrolysed peptide used for skin or hair conditioning. Cosmetic safety reviewers concluded that the assessed skin and connective-tissue-derived proteins are safe in current practices, subject to appropriate animal-source and impurity controls. Protein sensitivity remains possible.
Sources: CIR: Safety Assessment of Skin and Connective Tissue-Derived Proteins and Peptides as Used in Cosmetics https://www.cir-safety.org/sites/default/files/tsupep092017final.pdf
A yeast-derived ferment, filtrate or extract used for skin conditioning. Cosmetic safety reviewers concluded that cosmetic ingredients derived from the reviewed yeast species are safe in current practices; this record applies to the standardized cosmetic INCI material, not an unspecified live culture.
Sources: CIR: Yeast-derived ingredients final assessment, June 2024; Galactomyces Ferment Filtrate conclusion; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
High-water-binding humectant used to support hydration at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Water, Collagen Water, Butylene Glycol, 1,2-Hexanediol, Polyglyceryl-10 Laurate, Glycerin, Ethylhexylglycerin, Arginine, Allantoin, Carbomer, Xanthan Gum, Disodium EDTA, Sodium Polyacrylate, Cyanocobalamin, Palmitoyl Tripeptide-5, Hydrolyzed Hyaluronic Acid, Collagen Extract, Hydrolyzed Elastin, Galactomyces Ferment Filtrate, Hyaluronic Acid, Sh-Polypeptide-22, Sh-Oligopeptide-1, Sh-Polypeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-3
Ingredient ratings refreshed 1 October 2026. Formulas vary by market and can change. Always compare with your packaging.
Contains recombinant human growth-factor-style peptide(s): sh-oligopeptide-1, sh-oligopeptide-2, sh-polypeptide-1. These are not currently treated as known pregnancy-restricted ingredients in normal topical cosmetic use, but pregnancy-specific data are limited and they are biologically framed signaling peptides/proteins. MamaSkin scores them conservatively as low risk. This applies to topical cosmetic products only, not injectable growth-factor treatments, microneedling serums, wound use, or oral supplements. The product score is a stored assessment, not a clinical safety guarantee.
25 of 25 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.
No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.