Celimax
Celimax Pore + Dark Spot Brightening Cream
Low risk75/100
Is it suitable during pregnancy?
MamaSkin rates the recorded formula for Celimax Cica Serum as Low risk (79/100). Review the ingredient context and any manual-review explanation before deciding.
Why this rating? Manual-review explanation
Manual review 2026-07-13: The recorded formula was manually reviewed. This formula contains dipotassium glycyrrhizate, classified as low risk under MamaSkin's pregnancy-screening policy. This is a cautious classification, not a known pregnancy contraindication; see the highlighted ingredient entry for its rationale and sources.
39 of 39 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
How we assess productsIngredient breakdown
The recorded formula, with evidence behind each rating. Unmatched ingredients are marked Not assessed in grey.
Ingredient ratings and evidence
Higher-risk flags first. Open an ingredient for evidence.
dipotassium glycyrrhizate
Low risk
A purified glycyrrhizic-acid salt used as a soothing and skin-conditioning ingredient. Cosmetic safety reviewers concluded that dipotassium glycyrrhizate is safe in current cosmetic use and noted poor dermal absorption. MamaSkin nevertheless applies a cautious low-risk classification for consistency with the existing licorice family because high oral glycyrrhizin exposure has pregnancy-related concerns; this is not a topical contraindication.
Sources: CIR: Safety Assessment of Glycyrrhizic Acid and Derivatives https://cir-reports.cir-safety.org/view-attachment/?id=49a63435-8e74-ec11-8943-0022482f06a6
glycyrrhiza uralensis root extract
Low risk
Glycyrrhiza uralensis root extract is a Chinese-licorice extract that can contain glycyrrhizin and related biologically active constituents. Oral licorice exposure is not equivalent to the much smaller and formulation-dependent exposure from a topical cosmetic. MamaSkin applies a precautionary Low Risk classification for consistency with its existing Glycyrrhiza glabra, licorice-root and glycyrrhetinic-family policy.
Sources: CIR: Final Report on the Safety Assessment of Licorice-Derived Ingredients, including Glycyrrhiza Uralensis Root Extract https://cir-reports.cir-safety.org/view-attachment/?id=7c9aa17d-8c74-ec11-8943-0022482f06a6; PubMed: Glycyrrhiza uralensis root constituents including glycyrrhizin https://pubmed.ncbi.nlm.nih.gov/8448820/; PubMed: pregnancy outcomes after oral licorice exposure https://pubmed.ncbi.nlm.nih.gov/23299757/; existing MamaSkin licorice-family policy.
polygonum cuspidatum root extract
Low risk
Polygonum cuspidatum root extract, also called Japanese knotweed root extract, is a botanical source of resveratrol, polydatin and related polyphenols. Extract composition and cosmetic concentration vary, and normal topical exposure is expected to be much lower than high-dose oral supplementation. MamaSkin applies a precautionary Low Risk classification for consistency with its existing topical resveratrol policy, not because cosmetic use is a known pregnancy contraindication.
Sources: PubMed: Polygonum cuspidatum root contains resveratrol, polydatin and emodin https://pubmed.ncbi.nlm.nih.gov/23075087/; PubMed: Polygonum cuspidatum as a concentrated resveratrol source https://pubmed.ncbi.nlm.nih.gov/29403824/; PubMed: cautionary pregnancy findings from high-dose oral resveratrol in nonhuman primates https://pubmed.ncbi.nlm.nih.gov/24563374/; PubMed: topical resveratrol delivery and skin disposition https://pubmed.ncbi.nlm.nih.gov/28389713/; existing MamaSkin resveratrol policy.
1,2-hexanediol
No known risks
1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.
Sources: CIR; EU/UK Cosmetics Regulation
allantoin
No known risks
Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Show all 39 ingredients
asiatic acid
No known risks
A triterpene associated with Centella asiatica and used in skin-conditioning formulas. Pregnancy-specific evidence for isolated topical asiatic acid is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but identified asiatic acid and related constituents as potential contributors to sensitisation. No pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
asiaticoside
No known risks
A triterpene glycoside associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical asiaticoside is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but noted that asiaticoside and related triterpenes may contribute to sensitisation. No pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
beta-glucan
No known risks
Film-forming polysaccharide used for soothing and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
biosaccharide gum-1
No known risks
Microbial polysaccharide used for film forming, soothing, and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
butylene glycol
No known risks
Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
camellia sinensis leaf extract
No known risks
Camellia sinensis (green tea) leaf extract is used as an antioxidant botanical; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks, though rare sensitivities are possible.
Sources: CIR; EU/UK Cosmetics Regulation
caprylyl glycol
No known risks
Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
carbomer
No known risks
Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
centella asiatica extract
No known risks
Botanical skin-conditioning ingredient used in soothing and barrier-support formulas. Reviewed cosmetic safety sources support current cosmetic use when formulated to be non-sensitising, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Centella asiatica-derived Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
chamomilla recutita flower extract
No known risks
A German chamomile flower extract used for skin conditioning and soothing. Cosmetic safety reviewers concluded that Chamomilla recutita flower-derived ingredients are safe in current cosmetic use when formulated to be non-sensitizing. Chamomile can cause contact allergy in susceptible people, particularly those sensitive to plants in the Asteraceae family, but no pregnancy-specific concern is identified for normal topical cosmetic exposure.
Sources: CIR: Safety Assessment of Chamomilla Recutita-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-chamomilla-recutita-derived-ingredients-used-cosmetics-0
dipropylene glycol
No known risks
Dipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
disodium edta
No known risks
Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
ethylhexylglycerin
No known risks
Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
glycerin
No known risks
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
glyceryl acrylate/acrylic acid copolymer
No known risks
A high-molecular-weight polymer used to hold water and stabilise texture. Cosmetic safety reviewers concluded that glyceryl acrylate/acrylic acid copolymer is safe in current cosmetic practices. Dermal absorption of the finished polymer is expected to be limited; residual monomers should be controlled by cosmetic manufacturing standards.
Sources: CIR: Safety Assessment of Glyceryl Acrylate/Acrylic Acid Copolymer and Glyceryl Polyacrylate https://cir-reports.cir-safety.org/view-attachment/?id=c79ac89b-d78d-055f-ba88-45f4f5a039b3
hydrolyzed hyaluronic acid
No known risks
Humectant and skin-conditioning ingredient in the hyaluronate family. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
hydroxyacetophenone
No known risks
Hydroxyacetophenone is used as an antioxidant and preservative-support ingredient; it is generally considered low concern in topical cosmetic use with no known pregnancy or breastfeeding risks at typical concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
hydroxyethyl urea
No known risks
A humectant that helps skin and hair retain water. Cosmetic safety reviewers concluded that hydroxyethyl urea is safe in current cosmetic use when formulated to be non-irritating; reproductive and developmental data reviewed for the assessment did not identify a pregnancy-specific concern from normal topical exposure.
Sources: CIR: Safety Assessment of Hydroxyethyl Urea https://www.cir-safety.org/supplementaldoc/safety-assessment-hydroxyethyl-urea-used-cosmetics-0
madecassic acid
No known risks
A triterpene associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical madecassic acid is limited. Evidence for the related Centella ingredient family supports current cosmetic exposure when products are formulated to avoid sensitisation; no pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
madecassoside
No known risks
A triterpene glycoside associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical madecassoside is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but noted that madecassoside and related triterpenes may contribute to sensitisation, so products should be formulated to avoid sensitising concentrations. No pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
melia azadirachta flower extract
No known risks
Neem flower extract is used as a botanical skin-conditioning ingredient. A high-dose oral rat study altered the oestrous cycle and ovulation but did not show anti-implantation, abortifacient, or teratogenic effects. That oral dose does not establish a hazard from normal topical cosmetic exposure.
Sources: PubMed: high-dose oral neem flower extract reproductive study in rats https://pubmed.ncbi.nlm.nih.gov/19357745/; European Commission CosIng ingredient inventory. No human pregnancy study of normal topical cosmetic use was identified.
melia azadirachta leaf extract
No known risks
Neem leaf extract is used topically for skin conditioning and antimicrobial support. Reproductive concerns reported for concentrated neem seed preparations, intrauterine exposure, or high oral doses do not establish a hazard from normal topical cosmetic exposure to a leaf extract.
Sources: PubMed: oral purified neem seed extracts in primates https://pubmed.ncbi.nlm.nih.gov/8773426/; PubMed: intrauterine neem oil in primates https://pubmed.ncbi.nlm.nih.gov/8143455/; European Commission CosIng ingredient inventory. No human pregnancy study of normal topical cosmetic leaf-extract use was identified.
niacinamide
No known risks
Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
panthenol
No known risks
Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
portulaca oleracea extract
No known risks
A purslane extract used mainly for skin conditioning. Cosmetic safety reviewers concluded that Portulaca oleracea extract is safe in current cosmetic practices when formulated to be non-sensitising. Botanical irritation or allergy remains possible, but no pregnancy-specific concern was identified for normal topical use.
Sources: CIR: Safety Assessment of Portulaca oleracea-Derived Ingredients as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=5c0d093e-6947-f945-8d16-43dd820a5e63
pvm/ma copolymer
No known risks
A high-molecular-weight film-forming copolymer used in hair, oral-care and skin products. Cosmetic safety reviewers concluded that PVM/MA copolymer is safe in current practices of use and concentration. Absorption of the intact polymer is expected to be limited.
Sources: CIR: Safety Assessment of PVM/MA Copolymer and Its Esters, IJT 30(Suppl. 2), 2011; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
rosmarinus officinalis leaf extract
No known risks
Plant extract used for antioxidant or soothing properties. Unlike essential oils, cosmetic extracts are not highly concentrated and are used at low levels. Safety concerns associated with essential oil use do not generally apply to cosmetic extracts.
Sources: General cosmetic safety references for botanical extracts and exposure route considerations; essential oil literature discusses concentrated volatile forms rather than dilute extracts.
scutellaria baicalensis root extract
No known risks
A Chinese skullcap root extract used for skin conditioning and antioxidant effects. Cosmetic safety reviewers concluded that the root extract is safe in current practices of use and concentration; this conclusion does not extend to the generic whole-plant or sprout extracts, for which evidence was insufficient. No pregnancy-specific concern was identified for normal topical cosmetic exposure.
Sources: CIR: Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=12155820-bce2-80f8-bd06-353ba20e5877
sodium acetylated hyaluronate
No known risks
Modified hyaluronate humectant and skin-conditioning ingredient. Reviewed cosmetic safety sources support topical hyaluronate ingredients, with no pregnancy- or breastfeeding-specific concern identified for normal cosmetic use.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
sodium hyaluronate
No known risks
Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
tocopherol
No known risks
Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
trehalose
No known risks
Sugar-derived humectant used to help bind water and improve skin feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.
Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
tromethamine
No known risks
pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Tromethamine as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
water
No known risks
Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en
Full recorded ingredient list
1,2-hexanediol, allantoin, asiatic acid, asiaticoside, beta-glucan, biosaccharide gum-1, butylene glycol, camellia sinensis leaf extract, caprylyl glycol, carbomer, centella asiatica extract, chamomilla recutita flower extract, dipotassium glycyrrhizate, dipropylene glycol, disodium edta, ethylhexylglycerin, glycerin, glyceryl acrylate/acrylic acid copolymer, glycyrrhiza uralensis root extract, hydrolyzed hyaluronic acid, hydroxyacetophenone, hydroxyethyl urea, madecassic acid, madecassoside, melia azadirachta flower extract, melia azadirachta leaf extract, niacinamide, panthenol, polygonum cuspidatum root extract, portulaca oleracea extract, pvm/ma copolymer, rosmarinus officinalis leaf extract, scutellaria baicalensis root extract, sodium acetylated hyaluronate, sodium hyaluronate, tocopherol, trehalose, tromethamine, water
Ingredient ratings refreshed 29 October 2026. Formulas vary by market and can change. Always compare with your packaging.
Questions about this assessment
Why does Celimax Cica Serum have a Low risk rating?
Manual review 2026-07-13: The recorded formula was manually reviewed. This formula contains dipotassium glycyrrhizate, classified as low risk under MamaSkin's pregnancy-screening policy. This is a cautious classification, not a known pregnancy contraindication; see the highlighted ingredient entry for its rationale and sources. The product score is a stored assessment, not a clinical safety guarantee.
Is the licorice-derived ingredient the same as drinking licorice tea?
No. The recorded formula lists a licorice-derived cosmetic ingredient, not an oral licorice product. Different ingredients and routes of exposure should not be treated as interchangeable. Use the exact ingredient's rating and evidence below, together with any manual-review note; this score does not assess teas, supplements or other licorice formulas.
Has every ingredient in Celimax Cica Serum been assessed?
39 of 39 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
Does this assessment apply to my Celimax Cica Serum?
Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.
Does this pregnancy assessment also establish breastfeeding suitability?
No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.
