Ethylhexyl Methoxycinnamate
Medium RiskEthylhexyl methoxycinnamate (EHMC) is a UV-B filter (also called octinoxate/octyl methoxycinnamate). SCCS characterised EHMC as endocrine-active (oestrogenic activity and weak anti-androgenic activity in vitro and in vivo) and reviewed genotoxicity/reproductive toxicity datasets in its re-evaluation. Pregnancy-specific human outcome data for topical exposure are limited; the medium-risk signal is endocrine activity plus systemic exposure uncertainty with frequent, large-area use.
Sources: SCCS/1671/24: Ethylhexyl methoxycinnamate https://health.ec.europa.eu/publications/sccs-opinion-ethylhexyl-methoxycinnamate-ehmc-cas-no-5466-77-383834-59-7-ec-no-226-775-7629-661-9_en



