
COSRX The 6 Peptide Skin Booster Serum
Safety score
Pregnancy-focused assessment
No higher-risk ingredients were identified in MamaSkin's current assessment. Check the latest package before deciding.
Ingredient safety review updated 24 November 2025.
Ingredient breakdown
See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.
44
No known risks
0
Low risk
0
Medium risk
0
High risk
Ingredients
Ingredients with a higher risk flag appear first, followed by the rest of the formula.
Dipropylene Glycol
No Known RisksDipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Glycerin
No Known RisksGlycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Show all (44)
Pentylene Glycol
No Known RisksHumectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
1,2-Hexanediol
No Known Risks1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.
Sources: CIR; EU/UK Cosmetics Regulation
Niacinamide
No Known RisksNiacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Acetyl Hexapeptide-8
No Known RisksSynthetic peptide used as a skin-conditioning ingredient. Reviewed cosmetic safety sources do not indicate a known pregnancy- or breastfeeding-specific concern in normal topical cosmetic use. The available cosmetic safety assessment concluded this ingredient is safe in cosmetics at concentrations up to 0.005%; safety above that concentration was not established in the reviewed report.
Sources: CIR Expert Panel, Safety Assessment of Acetyl Hexapeptide-8 Amide as Used in Cosmetics, final report, 2021
Copper Tripeptide-1
No Known RisksCopper-binding carrier peptide also known as GHK-Cu, used topically in cosmetic skin-renewal, anti-aging, barrier-support and hair/scalp products. Reviewed literature describes topical cosmetic use and does not identify a pregnancy- or breastfeeding-specific risk signal for normal topical use. This assessment does not apply to injectable copper peptides or oral peptide/copper supplementation.
Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. doi:10.3390/cosmetics4020016; Pickart L et al. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. Int J Mol Sci. 2018;19(7):1987. doi:10.3390/ijms19071987.
Sh-Polypeptide-121
No Known RisksDipeptide Diaminobutyroyl Benzylamide Diacetate
No Known RisksSynthetic peptide mimetic used in topical cosmetic anti-aging formulas, often described as a neurotransmitter-inhibiting or expression-line peptide. Available cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.
Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. doi:10.3390/cosmetics4020016; EU CosIng / INCI cosmetic ingredient references.
Oligopeptide-68
No Known RisksPalmitoyl Tripeptide-8
No Known RisksAllantoin
No Known RisksAllantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Sodium Hyaluronate
No Known RisksSodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Acetyl Glucosamine
No Known RisksAn amino-sugar derivative used for skin conditioning and hydration. Cosmetic safety reviewers concluded that acetyl glucosamine is safe in current practices when formulated to be non-irritating. No pregnancy-specific concern was identified for normal topical cosmetic exposure.
Sources: CIR: Safety Assessment of Glucosamine Ingredients as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-glucosamine-ingredients-used-cosmetics-1
Serine
No Known RisksAmino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Alanine
No Known RisksAmino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Glycine
No Known RisksAmino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Threonine
No Known RisksAmino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Arginine
No Known RisksAmino acid used as a humectant, skin-conditioning agent, and pH-adjusting support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of α-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Proline
No Known RisksAmino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Betaine
No Known RisksBetaine is a humectant/osmolyte used to support hydration and reduce irritation potential in formulas; it is considered low concern with no known pregnancy or breastfeeding risks in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Sodium PCA
No Known RisksNatural-moisturising-factor humectant that helps bind water in the stratum corneum. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of PCA and Its Salts as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Sodium Lactate
No Known RisksHumectant and buffer that also forms part of the skin's natural moisturising factor. Reviewed cosmetic safety sources support topical cosmetic use; irritation and sun-sensitivity considerations relate more to formula context than to pregnancy-specific risk.
Sources: CIR: Safety Assessment of Alpha Hydroxy Acids as Used in Cosmetics; CIR: PCA and Its Salts as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
PCA
No Known RisksPyrrolidone carboxylic acid, a natural-moisturising-factor component used as a humectant. Cosmetic safety reviewers concluded that PCA and its salts are safe in current practices, but they should not be used in formulations where N-nitroso compounds can form. No pregnancy-specific concern was identified for compliant topical use.
Sources: CIR: Safety Assessment of PCA and Its Salts as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-pca-2-pyrrolidone-5-carboxylic-acid-and-its-salts-used-cosmetics-0
Glutamic Acid
No Known RisksThis naturally occurring alpha-amino acid is used for humectancy and skin or hair conditioning. The Cosmetic Ingredient Review found alpha-amino acids safe in current cosmetic use; the low concentrations and limited dermal uptake are not expected to create a pregnancy- or breastfeeding-specific concern.
Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-%CE%B1-amino-acids-used-cosmetics
Lysine Hcl
No Known RisksAn amino acid or amino-acid salt used for conditioning, buffering or hydration. Cosmetic safety reviewers concluded that the assessed animal- and plant-derived amino acids are safe in current practices of use and concentration. No pregnancy-specific concern was identified for normal topical exposure.
Sources: CIR: Safety Assessment of Animal- and Plant-Derived Amino Acids as Used in Cosmetics; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
Tocopherol
No Known RisksVitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Dextran
No Known RisksA high-molecular-weight carbohydrate gum produced by microbial fermentation and used for hydration, texture or film formation. Cosmetic safety reviewers concluded that the assessed microbial polysaccharide gums are safe in current practices of use and concentration. Dermal absorption of the intact polymers is expected to be limited.
Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=c052d083-8e74-ec11-8943-0022482f06a6
Glycine Soja Oil
No Known RisksPlant-derived emollient oil used to soften skin and support formula texture. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Soy-Derived Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Hydrogenated Lecithin
No Known RisksHydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.
Sources: Cosmetic Ingredient Review (US)
Ammonium Acryloyldimethyltaurate/Vp Copolymer
No Known RisksPolymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Polyacrylate Crosspolymer-6
No Known RisksLarge polymer thickener and stabilizer used in gels, serums and creams. Systemic exposure from topical cosmetic use is expected to be low, with no pregnancy- or breastfeeding-specific concern identified in reviewed cosmetic references.
Sources: CIR cosmetic ingredient safety references for acrylates/polyacrylate crosspolymers; EU CosIng / cosmetics regulatory inventory
Butylene Glycol
No Known RisksSolvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Xanthan Gum
No Known RisksNatural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.
Sources: European cosmetics regulatory framework
Ethylhexylglycerin
No Known RisksPreservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Adenosine
No Known RisksSkin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Polyquaternium-51
No Known RisksA large phosphorylcholine-containing conditioning polymer. Cosmetic safety reviewers concluded that acryloyloxyethyl phosphorylcholine polymers, including polyquaternium-51, are safe in current practices. Available testing did not indicate sensitisation, and dermal absorption of the finished polymer is expected to be limited.
Sources: CIR: Safety Assessment of Acryloyloxyethyl Phosphorylcholine Polymers as Used in Cosmetics https://www.cir-safety.org/sites/default/files/FR_AcryloyloxyethylPhosphorylcholinePolymers_062022.pdf
Disodium EDTA
No Known RisksDisodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Citric Acid
No Known RiskspH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Caprylyl Glycol
No Known RisksHumectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
T-Butyl Alcohol
No Known RisksA volatile solvent and denaturant used in small amounts in cosmetics. Cosmetic safety reviewers concluded that t-butyl alcohol is safe in current practices of use and concentration; their assessment included reproductive and developmental data and found a large exposure margin at cosmetic use levels. It may irritate eyes or skin in concentrated form.
Sources: CIR: Amended Safety Assessment of t-Butyl Alcohol as Used in Cosmetics https://cir-safety.org/sites/default/files/FAR_t-ButylAlcohol_092024.pdf
Potassium Sorbate
No Known RisksPreservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Sodium Oleate
No Known RisksFormulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.
How to use this assessment
The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.
MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.




