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Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.

Methylxanthine used in cosmetics (e.g., de-puffing/firming and antioxidant support). No pregnancy-specific contraindications are identified for topical cosmetic use.

A cucumber fruit extract used for skin conditioning. Cosmetic safety reviewers concluded that Cucumis sativus-derived ingredients are safe in current cosmetic practices of use and concentration when formulated to avoid sensitisation. No pregnancy-specific concern was identified for normal topical cosmetic exposure, although irritation or allergy to a botanical-containing formula remains possible.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

An oat kernel extract used for skin conditioning and soothing. Cosmetic safety reviewers concluded that Avena sativa kernel extract and most assessed oat-derived ingredients are safe in current practices of use and concentration when formulated to be non-sensitising and manufactured with appropriate impurity controls. Oat allergy or contact sensitivity can occur in susceptible people, but no pregnancy-specific concern was identified for normal topical cosmetic exposure.

Synthetic peptide used as a skin-conditioning ingredient. Reviewed cosmetic safety sources do not indicate a known pregnancy- or breastfeeding-specific concern in normal topical cosmetic use. The available cosmetic safety assessment concluded this ingredient is safe in cosmetics at concentrations up to 0.005%; safety above that concentration was not established in the reviewed report.

A terpene alcohol used for skin conditioning and soothing. Cosmetic safety reviewers reaffirmed bisabolol as safe at current cosmetic concentrations, and reproductive and developmental testing did not identify adverse effects. Bisabolol can increase skin penetration, so formulators should consider the safety of other ingredients in the same product.

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Camellia sinensis (green tea) leaf extract is used as an antioxidant botanical; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks, though rare sensitivities are possible.

Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Plant-derived emollient oil used to soften skin and improve formula feel. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

A botanical extract, plant water or plant juice used for conditioning, soothing or antioxidant support. Direct pregnancy studies of this exact cosmetic material were not identified, but no reproductive or developmental hazard was identified for normal topical exposure. Oral herbal or medicinal use is outside this classification.

A pomegranate fruit extract used mainly for skin conditioning and antioxidant effects. Cosmetic safety reviewers concluded that Punica granatum fruit extract is safe in current practices when formulated to be non-irritating and non-sensitising. The conclusion is ingredient-specific and does not extend to generic whole-plant pomegranate extract.

A fruit, seed or food-plant extract used for skin conditioning and antioxidant support. No pregnancy-specific signal was identified for the low topical exposure expected from a finished cosmetic. Direct pregnancy studies are generally unavailable, and botanical allergy remains possible.

A cosmetic extract from an edible fruit, seed, grain, root or mushroom used for conditioning or antioxidant support. Normal topical cosmetic exposure is much lower than ordinary dietary exposure to the source material, and no pregnancy-specific hazard signal was identified. Exact extract composition varies, so source quality and individual food or plant allergy remain relevant.

Star-anise fruit extract is used for skin conditioning and fragrance. Oral medicinal preparations and essential oils are not equivalent to a dilute fruit extract in a finished cosmetic. No pregnancy-specific systemic hazard was identified for normal topical cosmetic use.

A botanical root extract used as a skin-conditioning and antioxidant ingredient. Cosmetic safety reviewers concluded that Panax root-derived ingredients are safe in current practices of use and concentration. The assessment considered the biological activity of ginsenosides and available reproductive and developmental information; ordinary topical cosmetic exposure was not identified as a pregnancy-specific concern. Botanical irritation or allergy remains possible.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

An antioxidant peptide naturally present in the body and used in topical products for skin conditioning and tone. Clinical studies and systematic reviews report generally good tolerance of topical glutathione, although evidence for cosmetic benefits remains limited. No pregnancy-specific topical signal was identified.

Chelating agent used to improve formula stability. Used at low levels and not associated with pregnancy-specific concerns.

This sugar or sugar alcohol is used as a humectant and skin-conditioning ingredient. Cosmetic Ingredient Review assessments support these saccharides in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.

Cellulose-derived thickener and binder used to stabilise texture. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

A high-molecular-weight carbohydrate gum produced by microbial fermentation and used for hydration, texture or film formation. Cosmetic safety reviewers concluded that the assessed microbial polysaccharide gums are safe in current practices of use and concentration. Dermal absorption of the intact polymers is expected to be limited.

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Polymer used for texture and absorbency. Large-molecule ingredient with low systemic exposure.

calcium lactate is a cosmetic formulation or conditioning ingredient. Available identity, use and related safety evidence did not identify a pregnancy-specific concern for normal topical cosmetic exposure. This classification does not remove ordinary irritation or sensitivity precautions.

Starch-derived polysaccharide used as a binder, film former and texture support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

A plant-derived carbohydrate polymer or modified starch used to thicken, stabilise or condition a formula. Cosmetic safety reviewers concluded that the supported plant polysaccharide gums and derivatives are safe in current practices of use and concentration. Loose powders should still be used without deliberately inhaling airborne particles.

A common inorganic electrolyte used to control viscosity, stabilise a formula or condition skin. At cosmetic concentrations these salts do not present a pregnancy-specific concern; concentrated formulas can still sting damaged or very sensitive skin.

Hydroxyacetophenone is used as an antioxidant and preservative-support ingredient; it is generally considered low concern in topical cosmetic use with no known pregnancy or breastfeeding risks at typical concentrations.

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Solvent and humectant used to improve texture and ingredient solubility in topical cosmetics. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

A plant-derived carbohydrate polymer or modified starch used to thicken, stabilise or condition a formula. Cosmetic safety reviewers concluded that the supported plant polysaccharide gums and derivatives are safe in current practices of use and concentration. Loose powders should still be used without deliberately inhaling airborne particles.

A plant-derived carbohydrate polymer or modified starch used to thicken, stabilise or condition a formula. Cosmetic safety reviewers concluded that the supported plant polysaccharide gums and derivatives are safe in current practices of use and concentration. Loose powders should still be used without deliberately inhaling airborne particles.

Synthetic mica-like mineral used for bulking, optical effect, and texture. CIR concluded it is safe as used in cosmetics; normal topical use is not associated with a pregnancy- or breastfeeding-specific topical signal in the material reviewed.

Colour Index name for ultramarines pigment. Used in makeup for blue/violet colour. In typical topical use it has very low dermal absorption and is generally considered acceptable in pregnancy and breastfeeding. If you prefer a cautious approach, avoid inhaling loose powders or sprays.

Colour Index name for titanium dioxide. Used as a pigment and (in some products) a mineral UV filter. For typical topical use in creams, lotions and makeup, systemic absorption is expected to be very low. Most concerns discussed in the literature relate to ingestion (E171) or inhalation from fine powders/sprays, and to nanoparticle characterisation. For routine topical cosmetic use, it is generally considered acceptable in pregnancy and breastfeeding; if you prefer a cautious approach, avoid inhaling loose powders or sprays.