Multi-Peptide Serum for Hair Density

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Methylxanthine used in cosmetics (e.g., de-puffing/firming and antioxidant support). No pregnancy-specific contraindications are identified for topical cosmetic use.

Sources: CIR (Methylxanthines); PubMed (NLM)

Synthetic peptide derivative used in topical hair/scalp and skin-conditioning formulas. Available cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. doi:10.3390/cosmetics4020016; EU CosIng / INCI cosmetic ingredient references.

Synthetic acetylated peptide used in topical cosmetic hair/scalp and skin-conditioning formulas. Available cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. doi:10.3390/cosmetics4020016; EU CosIng / INCI cosmetic ingredient references.

larix europaea wood extract is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not a concentrated essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

Sources: CIR ingredient-specific and botanical-family safety assessments; CIR Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng

A botanical extract, juice or water used primarily for skin conditioning, moisturising, soothing or antioxidant support. Direct pregnancy studies of the named cosmetic material were not identified. No reproductive or developmental hazard was identified for normal topical exposure to a compliant finished cosmetic; oral herbal or medicinal use is outside this classification.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant plant-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

A Chinese skullcap root extract used for skin conditioning and antioxidant effects. Cosmetic safety reviewers concluded that the root extract is safe in current practices of use and concentration; this conclusion does not extend to the generic whole-plant or sprout extracts, for which evidence was insufficient. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Sources: CIR: Safety Assessment of Scutellaria baicalensis-Derived Ingredients as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=12155820-bce2-80f8-bd06-353ba20e5877

A botanical extract, juice or water used primarily for skin conditioning, moisturising, soothing or antioxidant support. Direct pregnancy studies of the named cosmetic material were not identified. No reproductive or developmental hazard was identified for normal topical exposure to a compliant finished cosmetic; oral herbal or medicinal use is outside this classification.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant plant-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

glycine soja germ extract is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not a concentrated essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

Sources: CIR ingredient-specific and botanical-family safety assessments; CIR Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng

Red clover flower extract may contain isoflavones with oestrogen-like activity when consumed as a concentrated supplement. Oral supplement cautions are not evidence of a hazard from the much smaller topical exposure in a finished cosmetic. No pregnancy- or breastfeeding-specific risk from normal topical cosmetic use was identified.

Sources: NCCIH: Red Clover https://www.nccih.nih.gov/health/red-clover; European Commission CosIng ingredient inventory. No ingredient-specific topical pregnancy studies were identified.

Camellia sinensis (green tea) leaf extract is used as an antioxidant botanical; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks, though rare sensitivities are possible.

Sources: CIR; EU/UK Cosmetics Regulation

No pregnancy-specific harm has been identified for ordinary, correctly formulated topical cosmetic use of apigenin. This is a bounded defined cosmetic chemical assessment; direct pregnancy studies of the exact material are limited and oral, medicinal, damaged-skin or aerosol exposure is not included.

Sources: https://health.ec.europa.eu/publications/sccs-notes-guidance-testing-cosmetic-ingredients-and-their-safety-evaluation-12th-revision_en

A plant-derived triterpenoid used for skin conditioning and antioxidant support. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant ingredient-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

Amino acid used as a humectant, skin-conditioning agent, and pH-adjusting support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of α-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Amino acid used as a humectant and skin/hair-conditioning support ingredient. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.

Sources: CIR: Safety Assessment of alpha-Amino Acids as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

The calcium salt of gluconic acid, used mainly as a skin-conditioning or formulation-support ingredient. Cosmetic safety reviewers included calcium gluconate in their assessment of monosaccharides, disaccharides and related ingredients and concluded that the reviewed ingredients are safe in current cosmetic use. No pregnancy-specific concern is identified for normal topical exposure.

Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients https://www.cir-safety.org/supplementaldoc/safety-assessment-monosaccharides-disaccharides-and-related-ingredients-used-cosme-0

A soluble zinc salt used for formula support, oral-care functions or antimicrobial and astringent effects. Zinc is an essential nutrient, but concentrated Zinc Chloride can be irritating or corrosive. CIR concluded that the assessed zinc salts are safe in current cosmetic practices when formulated to be non-irritating. No pregnancy-specific concern was identified for the small topical exposure expected from a finished cosmetic.

Sources: CIR: Safety Assessment of Zinc Salts as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-zinc-salts-used-cosmetics-0; European Commission CosIng ingredient inventory.

A high-molecular-weight carbohydrate gum produced by microbial fermentation and used for hydration, texture or film formation. Cosmetic safety reviewers concluded that the assessed microbial polysaccharide gums are safe in current practices of use and concentration. Dermal absorption of the intact polymers is expected to be limited.

Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=c052d083-8e74-ec11-8943-0022482f06a6

Polysaccharide carrier and bulking agent used for texture and delivery support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Cellulose-derived thickener used to build viscosity and improve texture. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR Quick Reference Table / ingredient status (Hydroxyethylcellulose, Final Report 03/2009); EU CosIng / cosmetics regulatory inventory

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Sources: European cosmetics regulatory framework

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A solvent or preservative-support ingredient used to dissolve actives and stabilise a formula. No reproductive or pregnancy-specific signal was identified for the low concentrations used in finished topical cosmetics. Solvents can still increase local irritation or the delivery of other formula ingredients.

Sources: European Commission CosIng ingredient inventory; European Chemicals Agency substance information; published dermal and cosmetic-use data for dimethyl isosorbide, phenylpropanol and benzyl glycol.

Nonionic surfactant and solubiliser used to disperse oils and fragrance. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Polysorbates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

A polyether surfactant and solubiliser. Cosmetic safety reviewers concluded that PPG-26-Buteth-26 is safe in current cosmetic practices when formulated to be non-irritating and manufacturing impurities are controlled. This conclusion applies to this assessed ingredient rather than every lower-molecular-weight related polyether.

Sources: CIR: Safety Assessment of PPG-Buteths, PPG-Buteth-PEGs and PPG-Buteths-IPDI Copolymers https://cir-reports.cir-safety.org/view-attachment/?id=737fc8b6-8d74-ec11-8943-0022482f06a6

Solubilizer and emulsifier used to disperse oils and fragrance components in cosmetic formulas. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific concern identified.

Sources: CIR cosmetic ingredient safety references for PEG castor oil derivatives; EU CosIng / cosmetics regulatory inventory

Chelating ingredient used to improve formula stability by binding trace metals. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for chelating agents; EU CosIng / cosmetics regulatory inventory

An antioxidant and reducing agent used to protect cosmetic formulas and hair-colour systems. Sulfites can cause irritation or hypersensitivity in susceptible people, especially with inhalation exposure, but no pregnancy-specific hazard is identified for normal topical cosmetic use.

Sources: CIR ingredient record and safety assessment: Sodium Metabisulfite https://cir-safety.org/ingredient/sodium-metabisulfite

Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Preservative used to help protect formulas from microbial growth. Reviewed cosmetic safety sources support present cosmetic use; no pregnancy- or breastfeeding-specific topical concern was identified in the material reviewed, although some users may still notice local irritation or sensitivity.

Sources: CIR: Safety Assessment of Chlorphenesin as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory