Squalane Cleanser

A plant-derived fixed oil or lipid used as an emollient and skin-conditioning ingredient. Cosmetic safety review focuses on oxidation, irritation, impurities and source allergy; no pregnancy-specific reproductive or developmental hazard was identified for normal topical exposure.

Sources: CIR: Safety Assessment of Plant-Derived Fatty Acid Oils as Used in Cosmetics; European Commission CosIng ingredient inventory.

Common emollient derived from fatty acids and glycerin. Used to soften skin and improve texture without pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A sugar-derived humectant or starch hydrolysate used to retain moisture and support formula texture. Cosmetic safety reviewers concluded that the assessed saccharide humectants and hydrogenated starch hydrolysate are safe in current practices. Dermal absorption of larger carbohydrate materials is expected to be limited.

Sources: CIR: Saccharide Humectants safety assessment; Hydrogenated Starch Hydrolysate final report, September 2015; CIR December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

A sugar, starch, inulin or cellulose derivative used for emulsification, film formation, absorbency or formula texture. These carbohydrate-based materials are not expected to produce meaningful systemic exposure through intact skin, and related cosmetic safety assessments do not identify a reproductive or developmental hazard for normal use. Fine dry powder should not be deliberately inhaled.

Sources: CIR safety assessments of Starches and Modified Starches, Cellulose and Cellulose Derivatives, Saccharide Esters and Plant Polysaccharide Gums; CIR December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf; European Commission CosIng ingredient inventory.

Large polymer thickener and stabilizer used in gels, serums and creams. Systemic exposure from topical cosmetic use is expected to be low, with no pregnancy- or breastfeeding-specific concern identified in reviewed cosmetic references.

Sources: CIR cosmetic ingredient safety references for acrylates/polyacrylate crosspolymers; EU CosIng / cosmetics regulatory inventory

isoceteth-20 is used as a cosmetic surfactant, emulsifier or conditioning agent. Relevant cosmetic-safety assessments support use when formulated to be non-irritating and with appropriate impurity controls. Local skin or eye irritation is possible at higher concentrations, but no pregnancy-specific concern was identified for normal topical or rinse-off use.

Sources: CIR safety assessments of alkyl PEG ethers, N-acyl taurates, fatty amidopropyl amines and related cosmetic surfactants https://www.cir-safety.org/sites/default/files/taurat122015FR.pdf; CIR Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Polymer used for texture and absorbency. Large-molecule ingredient with low systemic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

hydroxymethoxyphenyl decanone is a cosmetic formulation, mineral, sugar-derived or organic-acid ingredient. Available identity, use and related safety evidence did not identify a pregnancy-specific concern for normal topical cosmetic exposure. Cosmetic-grade purity and ordinary irritation precautions remain applicable.

Sources: CIR ingredient and related-family safety assessments; CIR Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng

Chelating ingredient used to improve formula stability by binding trace metals. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for chelating agents; EU CosIng / cosmetics regulatory inventory

A naturally occurring hydroxy dicarboxylic acid used mainly to adjust pH, support exfoliation or condition skin. No pregnancy-specific systemic concern was identified for normal topical cosmetic exposure. At sufficiently high concentration or low pH, hydroxy acids can sting, irritate skin and increase sensitivity to other irritants; those local effects depend on the finished formulation rather than indicating reproductive toxicity.

Sources: CIR: Amended Safety Assessment of Malic Acid and Sodium Malate https://www.cir-safety.org/supplementaldoc/amended-safety-assessment-malic-acid-and-sodium-malate-used-cosmetics; CIR assessments of alpha-hydroxy acids as used in cosmetics; European Commission CosIng ingredient inventory for Malic Acid and Tartaric Acid.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Preservative used to help protect formulas from microbial growth. Reviewed cosmetic safety sources support present cosmetic use; no pregnancy- or breastfeeding-specific topical concern was identified in the material reviewed, although some users may still notice local irritation or sensitivity.

Sources: CIR: Safety Assessment of Chlorphenesin as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory