Ginseng Moist Sun Serum SPF 50+ PA++++

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A diester used as an emollient, solvent and plasticizer. After reviewing additional dermal, reproductive, developmental and genotoxicity data, cosmetic safety reviewers concluded that dibutyl adipate is safe in current cosmetic use and concentration. No pregnancy-specific concern is identified for normal topical cosmetic exposure.

Sources: CIR: Amended Final Report of the Safety Assessment of Dibutyl Adipate https://cir-reports.cir-safety.org/view-attachment?id=f1624b41-8e74-ec11-8943-0022482f06a6

Modern UVA filter (often called Uvinul A+ or DHHB). Regulatory assessments have repeatedly evaluated this filter as safe in cosmetic products at concentrations up to 10%. The most recent SCCS advice focuses on controlling a manufacturing impurity (DnHexP) rather than on new toxicity of DHHB itself. Human biomonitoring data indicate low systemic exposure from normal sunscreen use, and current reviews do not identify specific reproductive or developmental toxicity signals at approved concentrations.

Sources: SCCP opinion referenced in Directive 2008/123/EC: concludes that Diethylamino Hydroxybenzoyl Hexyl Benzoate used at a maximum of 10% in cosmetic (including sunscreen) products does not pose a risk to the consumer. Regulatory summaries (e.g. CosLaw and CIRS Group updates, 2025) reviewing the SCCS DHHB opinion and reiterating that DHHB remains permitted up to 10% in EU cosmetics when impurity limits are respected.

Modern broad-spectrum UV filter (often known as Tinosorb S). It has a high molecular weight and is formulated to remain mainly in the outer skin layers, with very low systemic absorption at cosmetic use levels. EU regulatory assessments and independent risk–benefit reviews have evaluated this filter as safe up to 10% in sunscreens, with no specific reproductive or developmental toxicity signals identified in animals or humans at permitted concentrations.

Sources: European Union Cosmetic Products Regulation (Annex VI): Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine listed as an approved UV filter up to 10% in cosmetic products. Mikkelsen SH et al. “Survey and health assessment of UV filters” – Danish EPA, 2015: includes Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine and notes low systemic exposure at approved use levels.

Volatile solvent used in some toners, sprays, and lightweight formulas. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed; the main practical issue is dryness, stinging, or barrier disruption in some users.

Sources: CIR: Safety Assessment of SD Alcohol 40, Benzyl Alcohol, and Denatured Alcohol in Cosmetic Products; EU CosIng / cosmetics regulatory inventory

Film-forming polymer used for texture and wear. Large-molecule ingredient with low systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Alkyl benzoate emollient used in cosmetics; available cosmetic safety assessments do not indicate pregnancy-specific concerns with routine topical use.

Sources: CIR Safety Assessment of Alkyl Benzoates (2012); CIR alkyl benzoates dossier / C12-15 alkyl benzoate data.

UV filter used in sunscreens and day products to help absorb UVB radiation. Reviewed cosmetic safety and regulatory sources support current cosmetic use within applicable concentration limits, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

Sources: EU CosIng Annex VI / UV filters; EU scientific opinion on Ethylhexyl Triazone (Uvinul T 150)

The 2022 RIFM assessment concludes that phenethyl benzoate is safe as described; it reports no genotoxic concern, adequate repeated-dose and developmental margins, and no expected phototoxicity or photoallergenicity.

Sources: https://fragrancematerialsafetyresource.elsevier.com/sites/default/files/94-47-3.pdf, https://pubmed.ncbi.nlm.nih.gov/35306107/

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

Mineral absorbent and texture aid used to mattify and improve slip. Reviewed cosmetic safety sources support normal topical cosmetic use; this assessment does not cover deliberate inhalation of loose powder.

Sources: CIR: Safety Assessment of Silica and Silicates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Solvent and humectant used to improve texture and ingredient delivery in topical cosmetic formulas. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for alkane diols; EU CosIng / cosmetics regulatory inventory

Organic UVB filter used in sunscreens, also known as Amiloxate. Available cosmetic safety sources describe low dermal toxicity and no pregnancy-specific topical concern was identified in the sources reviewed. This is assessed separately from Ethylhexyl Methoxycinnamate/Octinoxate.

Sources: EU CosIng Annex VI / UV filters; SCC Opinion on Isopentyl-p-Methoxycinnamate; PubMed

Silicone-based organic UVB filter used in sunscreens and UV-protective cosmetics. SCCS reviewed Polysilicone-15 for cosmetic use, and no pregnancy- or breastfeeding-specific topical concern was identified in the sources reviewed.

Sources: EU CosIng Annex VI / UV filters; SCCS Opinion on Polysilicone-15 (SCCS/1346/10); PubMed

A silicone resin used as a film former, texture enhancer and opacifying ingredient in makeup, sunscreen and skin care. The Cosmetic Ingredient Review concluded that polysilsesquioxanes including Polymethylsilsesquioxane are safe in current cosmetic use. Available evidence does not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic exposure.

Sources: CIR: Safety Assessment of Polysilsesquioxanes as Used in Cosmetics (Final Report) https://cir-safety.org/sites/default/files/PLYSIL122017FR.pdf

A botanical root extract used as a skin-conditioning and antioxidant ingredient. Cosmetic safety reviewers concluded that Panax root-derived ingredients are safe in current practices of use and concentration. The assessment considered the biological activity of ginsenosides and available reproductive and developmental information; ordinary topical cosmetic exposure was not identified as a pregnancy-specific concern. Botanical irritation or allergy remains possible.

Sources: CIR: Safety Assessment of Panax spp. Root-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-panax-spp-root-derived-ingredients-used-cosmetics

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A fatty ester, lipid-derived emulsifier or emollient used for texture and skin conditioning. These materials have low expected systemic exposure, and no pregnancy-specific reproductive or developmental hazard was identified for normal topical cosmetic use.

Sources: CIR safety assessments of fatty esters, glycerides and emollients as used in cosmetics; European Commission CosIng ingredient inventory.

A fatty ester, lipid-derived emulsifier or emollient used for texture and skin conditioning. These materials have low expected systemic exposure, and no pregnancy-specific reproductive or developmental hazard was identified for normal topical cosmetic use.

Sources: CIR safety assessments of fatty esters, glycerides and emollients as used in cosmetics; European Commission CosIng ingredient inventory.

c30-45 alkyldimethylsilyl polypropylsilsesquioxane is a cosmetic formulation, mineral, sugar-derived or organic-acid ingredient. Available identity, use and related safety evidence did not identify a pregnancy-specific concern for normal topical cosmetic exposure. Cosmetic-grade purity and ordinary irritation precautions remain applicable.

Sources: CIR ingredient and related-family safety assessments; CIR Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng

Polymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A high-molecular-weight polymer used to thicken and stabilise cosmetics. CIR included Sodium Acrylates Crosspolymer-2 in the acrylates-copolymer safe-as-used conclusion when formulated to be non-irritating. This conclusion concerns the finished polymer with appropriate residual-monomer controls, not free acrylate monomers; no pregnancy-specific topical concern was identified.

Sources: CIR: Amended Safety Assessment of Acrylates Copolymers as Used in Cosmetics https://www.cir-safety.org/sites/default/files/Acrylates%20Copolymers_0.pdf

A high-molecular-weight polymer used to thicken and stabilise formulas. Cosmetic safety reviewers assessed acryloyldimethyltaurate polymers and concluded that they are safe in current cosmetic practices. Absorption of the finished polymer is expected to be limited, with residual monomers controlled during manufacture.

Sources: CIR: Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics https://www.cir-safety.org/panelbook/safety-assessment-acryloyldimethyltaurate-polymers-used-cosmetics-1

Hydroxyacetophenone is used as an antioxidant and preservative-support ingredient; it is generally considered low concern in topical cosmetic use with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

For ordinary topical cosmetic use, no pregnancy-specific harm has been established for panax ginseng berry extract. Berry distinct from root; live ginseng root extracts NKR; no topical pregnancy signal. Panax ginseng berry extract is not root extract; NCCIH ginseng guidance notes inadequate topical and pregnancy data. Direct human gestational studies and finished-product constituent levels are limited; oral, medicinal, and concentrated preparations are not covered.

Sources: https://www.nccih.nih.gov/health/asian-ginseng

For ordinary topical cosmetic use, no pregnancy-specific harm has been established for panax ginseng extract. Unspecified plant part; do not assume berry/root equivalence, but normal topical risk not identified. Generic Panax ginseng extract does not specify berry/root/other part. NCCIH cannot Direct human gestational studies and finished-product constituent levels are limited; oral, medicinal, and concentrated preparations are not covered.

Sources: https://www.nccih.nih.gov/health/asian-ginseng

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Sources: European cosmetics regulatory framework

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)