Ethylhexyl Methoxycinnamate
Medium RiskEthylhexyl methoxycinnamate (EHMC) is a UV-B filter (also called octinoxate/octyl methoxycinnamate). SCCS characterised EHMC as endocrine-active (oestrogenic activity and weak anti-androgenic activity in vitro and in vivo) and reviewed genotoxicity/reproductive toxicity datasets in its re-evaluation. Pregnancy-specific human outcome data for topical exposure are limited; the medium-risk signal is endocrine activity plus systemic exposure uncertainty with frequent, large-area use.
Sources: EU SCCS Opinion on Ethylhexyl Methoxycinnamate (EHMC) (SCCS/1671/24; sccs_o_294.pdf, final 26 Jun 2025).





