Black Rice Bakuchiol Eye Cream

Helianthus annuus (sunflower) seed oil is a common emollient rich in fatty acids and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Common emollient derived from fatty acids and glycerin. Used to soften skin and improve texture without pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

Fatty alcohol used to improve texture and skin feel. Considered safe for cosmetic use without pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Fatty alcohol used as an emollient and thickener. Not the same as drying alcohols and not associated with pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A long-chain fatty alcohol or fatty-alcohol blend used as an emollient, emulsifier or thickener. Cosmetic safety assessments of long-chain fatty alcohols support use in current cosmetic practices; systemic absorption and reproductive exposure from normal topical use are expected to be low.

Sources: CIR: Safety Assessment of Fatty Alcohols as Used in Cosmetics; CIR December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Bakuchiol is a plant-derived skincare ingredient used as a retinol alternative. Although it can show some retinol-like cosmetic effects, it is not a retinoid or vitamin A derivative. Human topical studies suggest good tolerability, and current literature does not identify a known pregnancy-specific risk signal for topical cosmetic use. Overall, it is generally considered a lower-concern alternative to retinoids in pregnancy, while recognising that direct pregnancy-specific studies remain limited.

Sources: PubMed (NLM): Chaudhuri & Bojanowski 2014 (PMID 24471735); Br J Dermatol bakuchiol vs retinol randomized trial (PMID 29947134); J Drugs Dermatol bakuchiol moisturizer trial in sensitive skin (PMID 33346506); J Drugs Dermatol systematic review of human topical bakuchiol trials (PMID 38564402); Contact Dermatitis case reports (PMIDs 30644106, 31423588); PMC review noting lack of pregnancy-specific studies (PMCID PMC10683784).

Fatty alcohol used as an emollient and stabiliser. Not associated with pregnancy-specific concerns at cosmetic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Sugar-based emulsifier used to stabilise creams and lotions. Reviewed cosmetic safety sources support topical cosmetic use; the relevant practical caveat is formulation irritation potential rather than a pregnancy-specific concern.

Sources: CIR: Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Tromethamine as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A rice-derived extract or wax used for skin conditioning, absorbency or texture. Cosmetic safety reviewers concluded that the assessed Oryza sativa-derived ingredients are safe in current cosmetic practices. Rice allergy remains possible in a susceptible person.

Sources: CIR: Rice-derived ingredients conclusions, IJT 25(Suppl. 2), 2006; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

A waxy fatty-acid ester used as an emollient and texture agent. Cosmetic safety reviewers concluded that cetyl palmitate and the wider alkyl-ester group are safe in current practices of use; finished formulas should be non-irritating. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Sources: CIR: Safety Assessment of Alkyl Esters as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=b34bc38f-8e74-ec11-8943-0022482f06a6

A sugar-derived surfactant and emulsifier. Cosmetic safety reviewers concluded that alkyl glucosides, including C12-20 alkyl glucoside, are safe in current practices when formulated to be non-irritating.

Sources: CIR: Alkyl Glucosides conclusion, IJT 32(Suppl. 3), 2013; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

A large synthetic polymer used to thicken and stabilise cosmetic emulsions. Related acrylate copolymers have low dermal absorption because of their molecular size, and cosmetic safety reviewers concluded that this polymer family is safe when formulas avoid irritation and residual monomers are appropriately controlled. Exact pregnancy-specific topical studies are limited, but no pregnancy-specific concern was identified for normal exposure to the finished polymer in a compliant cosmetic.

Sources: CIR: Amended Safety Assessment of Acrylates Copolymers as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment?id=c3a1aad1-8c74-ec11-8943-0022482f06a6; CIR: Final Report on Acrylates Copolymer and Related Ingredients https://cir-reports.cir-safety.org/view-attachment/?id=c9cc1a17-8e74-ec11-8943-0022482f06a6

A sorbitol-derived surfactant or emulsifier used to blend oil and water phases. Cosmetic safety reviewers concluded that the named sorbitan esters are safe in current practices, with non-irritating formulation conditions where specified.

Sources: CIR: Sorbitan Sesquiisostearate, Sorbitan Palmitate and Sorbeth-30 Tetraoleate conclusions; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Olive-derived sorbitan ester used as an emulsifier and skin-conditioning ingredient. Reviewed cosmetic safety references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR: Safety Assessment of Sorbitan Esters as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

A large, mostly insoluble polymer used as a binder, film former and texture ingredient. Cosmetic safety reviewers concluded that polyisobutene is safe in current cosmetic use; slow absorption and reproductive data on related polybutene do not indicate a pregnancy-specific concern from normal topical exposure.

Sources: CIR: Final Report on Polyisobutene and Hydrogenated Polyisobutene https://www.cir-safety.org/sites/default/files/polyene.pdf

A long-chain fatty alcohol used as an emollient, thickener and stabiliser. This is not the same concern profile as volatile drying alcohols; cosmetic safety reviewers concluded that myristyl and related fatty alcohols are safe in current practices. Local irritation is uncommon but possible.

Sources: CIR: Final Report on the Safety Assessment of Cetearyl Alcohol, Cetyl Alcohol, Isostearyl Alcohol, Myristyl Alcohol and Behenyl Alcohol; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

A botanical extract, juice or water used primarily for skin conditioning, moisturising, soothing or antioxidant support. Direct pregnancy studies of the named cosmetic material were not identified. No reproductive or developmental hazard was identified for normal topical exposure to a compliant finished cosmetic; oral herbal or medicinal use is outside this classification.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant plant-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

A fermentation-derived cosmetic ingredient used for conditioning or formula support. Composition depends on the organism, substrate and manufacturing controls. No pregnancy-specific reproductive or developmental hazard was identified for normal topical exposure; ingestion is outside this classification.

Sources: European Commission CosIng ingredient inventory; CIR safety framework for microbial, fermentation-derived and biological-source cosmetic ingredients.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

A botanical root extract used as a skin-conditioning and antioxidant ingredient. Cosmetic safety reviewers concluded that Panax root-derived ingredients are safe in current practices of use and concentration. The assessment considered the biological activity of ginsenosides and available reproductive and developmental information; ordinary topical cosmetic exposure was not identified as a pregnancy-specific concern. Botanical irritation or allergy remains possible.

Sources: CIR: Safety Assessment of Panax spp. Root-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-panax-spp-root-derived-ingredients-used-cosmetics

A plant-derived carbohydrate polymer or modified starch used to thicken, stabilise or condition a formula. Cosmetic safety reviewers concluded that the supported plant polysaccharide gums and derivatives are safe in current practices of use and concentration. Loose powders should still be used without deliberately inhaling airborne particles.

Sources: CIR: Safety Assessment of Plant Polysaccharide Gums as Used in Cosmetics https://www.cir-safety.org/panelbook/safety-assessment-plant-polysaccharide-gums-used-cosmetics

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

A long-chain fatty alcohol or fatty-alcohol blend used as an emollient, thickener or stabiliser. These are not volatile drying alcohols. CIR safety assessments support use of lauryl, oleyl and related fatty alcohols in current cosmetic practices, and no pregnancy-specific hazard signal was identified for normal topical exposure.

Sources: CIR: Safety Assessment of Fatty Alcohols as Used in Cosmetics; CIR December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

This glucose-derived nonionic surfactant or emulsifier is used in cleansers and emulsions. The Cosmetic Ingredient Review concluded that alkyl glucosides are safe in current cosmetic use when formulated to be non-irritating; sensitive skin can still react to surfactants.

Sources: CIR: Safety Assessment of Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=9810a771-8e74-ec11-8943-0022482f06a6

This sorbitan fatty-acid ester is an emulsifier that helps oil and water phases remain mixed. The Cosmetic Ingredient Review concluded that sorbitan esters are safe in current cosmetic use; occasional contact reactions remain possible in sensitive users.

Sources: CIR: Safety Assessment of Sorbitan Esters as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-sorbitan-esters-used-cosmetics

Simple sugar used as a humectant and skin-conditioning support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

An amino acid or amino-acid mixture used for hydration and conditioning. No pregnancy-specific hazard was identified for normal topical exposure.

Sources: European Commission CosIng; peer-reviewed biochemical and cosmetic literature.

natto gum is a fermentation-, microbial- or algae-derived cosmetic conditioning material. The assessment applies to the defined cosmetic ingredient rather than live organisms or oral supplements. No pregnancy-specific concern was identified for normal topical use; formulation purity and sensitivity remain relevant.

Sources: CIR assessments of microbial polysaccharides, fermentation-derived and algae-derived cosmetic ingredients; CIR Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

A triterpene glycoside associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical madecassoside is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but noted that madecassoside and related triterpenes may contribute to sensitisation, so products should be formulated to avoid sensitising concentrations. No pregnancy-specific topical contraindication was identified in the reviewed material.

Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1