La Roche-Posay Hyalu B5 Booster by La Roche-Posay
La Roche-Posay

La Roche-Posay Hyalu B5 Booster

Serums

Safety score

Pregnancy-focused assessment

No Known Risks99/100
Higher concernLower concern

No higher-risk ingredients were identified in MamaSkin's current assessment. Check the latest package before deciding.

Formula and assessment check

Ingredient safety review updated 24 November 2025. Product formulas can change, so compare the ingredients shown here with the packaging you have.

Report a formula mismatch

Ingredient breakdown

See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.

13

No known risks

0

Low risk

0

Medium risk

0

High risk

Ingredients

Ingredients with a higher risk flag appear first, followed by the rest of the formula.

Water

No Known Risks

Glycerin

No Known Risks

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Panthenol

No Known Risks

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Show all (13)

Propanediol

No Known Risks

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Pentylene Glycol

No Known Risks

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Sodium Hyaluronate

No Known Risks

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Sodium Acetylated Hyaluronate

No Known Risks

Modified hyaluronate humectant and skin-conditioning ingredient. Reviewed cosmetic safety sources support topical hyaluronate ingredients, with no pregnancy- or breastfeeding-specific concern identified for normal cosmetic use.

Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Adenosine

No Known Risks

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Copper Gluconate

No Known Risks

A mineral salt of gluconic acid used for skin conditioning or formula support. Cosmetic safety reviewers concluded that the assessed gluconate salts are safe in current practices when formulated to be non-irritating.

Sources: CIR: Zinc Gluconate final assessment, March 2018; Copper Gluconate final assessment, March 2025; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Hydrolyzed Hyaluronic Acid

No Known Risks

Humectant and skin-conditioning ingredient in the hyaluronate family. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Caprylyl Glycol

No Known Risks

Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Citric Acid

No Known Risks

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Trisodium Ethylenediamine Disuccinate

No Known Risks

Chelating ingredient used to improve formula stability by binding trace metals. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for chelating agents; EU CosIng / cosmetics regulatory inventory

Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.

How to use this assessment

The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.

MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.

Read the full methodology