La Roche-Posay
La Roche-Posay Toleriane Hydrating Gentle Cleanser
Face Cleanserscleansers
Safety score
Pregnancy-focused assessment
No Known Risks99/100
Higher concernLower concern
No higher-risk ingredients were identified in MamaSkin's current assessment. Check the latest package before deciding.
Ingredient safety review updated 24 November 2025.
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Ingredient breakdown
See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.
15
No known risks
0
Low risk
0
Medium risk
0
High risk
Ingredients
Ingredients with a higher risk flag appear first, followed by the rest of the formula.
Glycerin
No Known RisksGlycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Pentaerythrityl Tetraethylhexanoate
No Known RisksA high-molecular-weight tetraester used as an emollient, binder and texture agent. Cosmetic safety reviewers concluded that pentaerythrityl tetraesters, including pentaerythrityl tetraethylhexanoate, are safe in current practices of use and concentration. Dermal penetration is expected to be low.
Sources: CIR: Safety Assessment of Pentaerythrityl Tetraesters as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=7a10a771-8e74-ec11-8943-0022482f06a6
Show all (15)
Propylene Glycol
No Known RisksPropylene glycol is a common solvent and humectant with a long history of use; it is not considered a pregnancy or breastfeeding concern in topical cosmetics, though some individuals may experience irritation in leave-on products.
Sources: CIR; EU/UK Cosmetics Regulation
Ammonium Polyacryloyldimethyl Taurate
No Known RisksA high-molecular-weight polymer used to thicken and stabilise formulas. Cosmetic safety reviewers concluded that acryloyldimethyltaurate polymers are safe in current cosmetic practices. Absorption of the finished polymer is expected to be limited, with residual monomers controlled during manufacture.
Sources: CIR: Safety Assessment of Acryloyldimethyltaurate Polymers as Used in Cosmetics; final report April 2017 https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
Polysorbate 60
No Known RisksNonionic emulsifier and solubilizer used to help oil and water phases mix. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of Polysorbates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Ceramide NP
No Known RisksSkin-identical barrier lipid used to support the stratum corneum and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Ceramides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Niacinamide
No Known RisksNiacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Sodium Chloride
No Known RisksSodium chloride is used to adjust viscosity and texture in formulations; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks.
Sources: CIR; EU/UK Cosmetics Regulation
Coco-Betaine
No Known RisksA cleansing and foam-supporting surfactant made from coconut-derived fatty chains. Cosmetic safety reviewers concluded that alkyl betaines, including coco-betaine, are safe in current practices when formulated to be non-irritating. Surfactant-containing products may still sting eyes or irritated skin.
Sources: CIR: Quick Reference Table conclusion for Coco-Betaine and alkyl betaines https://www.cir-safety.org/sites/default/files/sq-fix_2.pdf
Disodium EDTA
No Known RisksDisodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Caprylyl Glycol
No Known RisksHumectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Panthenol
No Known RisksPanthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
T-Butyl Alcohol
No Known RisksA volatile solvent and denaturant used in small amounts in cosmetics. Cosmetic safety reviewers concluded that t-butyl alcohol is safe in current practices of use and concentration; their assessment included reproductive and developmental data and found a large exposure margin at cosmetic use levels. It may irritate eyes or skin in concentrated form.
Sources: CIR: Amended Safety Assessment of t-Butyl Alcohol as Used in Cosmetics https://cir-safety.org/sites/default/files/FAR_t-ButylAlcohol_092024.pdf
Tocopherol
No Known RisksVitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.
How to use this assessment
The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.
MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.
