MediCube Collagen Jelly Cream

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

Dipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Solvent and humectant used to improve texture and ingredient delivery in topical cosmetic formulas. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

A cosmetic ester or glyceride used mainly for emollience, texture, dispersion or emulsification. The relevant fatty-acid, glyceryl, sorbitan, polyglyceryl and related ester safety assessments support use in current cosmetic practices. No pregnancy-specific hazard signal was identified for normal topical exposure; local irritation remains formulation-dependent.

A glycol ether used as a cosmetic solvent and delivery aid. Cosmetic safety reviewers concluded that ethoxydiglycol is safe as used in cosmetics, with low toxicity in the reviewed exposure data. It is distinct from ethoxyethanol, which has a different and less favourable safety assessment.

A high-molecular-weight polymer used for film formation, texture or stabilisation. Meaningful dermal absorption is expected to be limited and no reproductive or developmental concern was identified for normal topical use.

Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.

Sugar-derived humectant used to help bind water and improve skin feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

An algae-derived skin-conditioning ingredient. Cosmetic safety reviewers concluded that Fucus vesiculosus extract is safe in current practices, and available cosmetic use information does not identify a pregnancy-specific concern for Chlorella vulgaris extract. Algae allergy remains possible; this entry assesses topical cosmetics rather than concentrated oral seaweed supplements.

A structural protein or hydrolysed peptide used for skin or hair conditioning. Cosmetic safety reviewers concluded that the assessed skin and connective-tissue-derived proteins are safe in current practices, subject to appropriate animal-source and impurity controls. Protein sensitivity remains possible.

Protein-derived skin- and hair-conditioning ingredient used to support feel and hydration at the surface. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

A botanical extract or plant water used for conditioning, soothing or antioxidant support. Direct pregnancy studies of this exact cosmetic material were not identified, but no reproductive or developmental hazard was identified for normal topical exposure. Oral herbal or medicinal use is outside this classification.

A botanical extract, juice or water used primarily for skin conditioning, moisturising, soothing or antioxidant support. Direct pregnancy studies of the named cosmetic material were not identified. No reproductive or developmental hazard was identified for normal topical exposure to a compliant finished cosmetic; oral herbal or medicinal use is outside this classification.

A collagen preparation used for skin and hair conditioning. Cosmetic safety reviewers concluded that soluble collagen and related connective-tissue proteins are safe in current practices, subject to source and impurity controls that exclude prohibited cattle materials. Protein sensitivity remains possible in susceptible people.

An oat kernel extract used for skin conditioning and soothing. Cosmetic safety reviewers concluded that Avena sativa kernel extract and most assessed oat-derived ingredients are safe in current practices of use and concentration when formulated to be non-sensitising and manufactured with appropriate impurity controls. Oat allergy or contact sensitivity can occur in susceptible people, but no pregnancy-specific concern was identified for normal topical cosmetic exposure.

A broccoli extract used for skin conditioning and antioxidant support. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.

camellia sinensis seed extract is a defined non-essential-oil botanical, food-derived or algae cosmetic ingredient. The reviewed identity and expected low topical exposure did not identify a pregnancy-specific reproductive or developmental concern. This classification does not extend to oral medicinal use, concentrated essential oils or contaminated raw materials, and botanical sensitivity remains possible.

A botanical extract, juice or water used primarily for skin conditioning, moisturising, soothing or antioxidant support. Direct pregnancy studies of the named cosmetic material were not identified. No reproductive or developmental hazard was identified for normal topical exposure to a compliant finished cosmetic; oral herbal or medicinal use is outside this classification.

spinacia oleracea leaf extract is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not an essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

A fruit, seed or food-plant extract used for skin conditioning and antioxidant support. No pregnancy-specific signal was identified for the low topical exposure expected from a finished cosmetic. Direct pregnancy studies are generally unavailable, and botanical allergy remains possible.

wine extract is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not a concentrated essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

polyglyceryl-10 isostearate is a cosmetic emollient, ester or lipid-derived formulation aid. Relevant family evidence supports normal cosmetic use with irritation, sensitisation and purity qualifications retained where applicable. No pregnancy-specific concern was identified for ordinary topical exposure.

pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Simple sugar used as a humectant and skin-conditioning support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

A polyglycerin fatty-acid ester used as an emulsifier, dispersant or emollient. Cosmetic safety reviewers concluded that the assessed family of 274 polyglyceryl fatty acid esters is safe in current practices when formulated to be non-irritating. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Short plant-derived carbohydrate chains used for skin conditioning and formula support. Cosmetic safety reviewers assessed fructooligosaccharides with plant polysaccharide gums and concluded that the group is safe in current practices. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

This sugar or sugar alcohol is used as a humectant and skin-conditioning ingredient. Cosmetic Ingredient Review assessments support these saccharides in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Chelating agent used to improve formula stability. Used at low levels and not associated with pregnancy-specific concerns.

A vitamin B ingredient or derivative used for skin or hair conditioning. These vitamins are normal nutrients and no pregnancy-specific concern was identified for the small topical exposure expected from a finished cosmetic. This assessment does not replace guidance about oral supplements or therapeutic doses.

Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.

A large polysaccharide produced by fermentation and used as a film former, binder and texture ingredient. Cosmetic safety reviewers concluded that microbial polysaccharide gums, including pullulan, are safe in current cosmetic use. Its large molecular size limits skin penetration, and no pregnancy-specific concern is identified for normal topical exposure.

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Cationic hyaluronate derivative used as a humectant and conditioning ingredient. Reviewed topical hyaluronate safety sources support cosmetic use, with no pregnancy- or breastfeeding-specific concern identified.

Lightweight emollient used to support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

soluble proteoglycan is an amino-acid, peptide, protein or related conditioning ingredient. Relevant cosmetic-family assessments support topical use, and expected systemic exposure is low. No pregnancy-specific concern was identified for normal intact-skin use; residual allergenic proteins and manufacturing quality remain relevant.

A structural protein or hydrolysed peptide used for skin or hair conditioning. Cosmetic safety reviewers concluded that the assessed skin and connective-tissue-derived proteins are safe in current practices, subject to appropriate animal-source and impurity controls. Protein sensitivity remains possible.

Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.