MediCube Zero Pore Pad

Ester form of salicylic acid; hydrolyses to SA, low-strength topical use shows negligible systemic absorption - chemical peels ≥30 % should be avoided.

Ethyl Hexanediol is an aliphatic alcohol used mainly as a cosmetic solvent. It can be absorbed through skin. Animal studies reported developmental effects after high oral and dermal doses, but those effects occurred at doses that also caused substantial maternal toxicity. CIR concluded that the ingredient is safe as cosmetically used and later reaffirmed that conclusion. MamaSkin nevertheless classifies it as low risk under its precautionary pregnancy-screening policy; this is not a known human pregnancy contraindication at normal cosmetic exposure.

Plant extract used for antioxidant or soothing properties. Unlike essential oils, cosmetic extracts are not highly concentrated and are used at low levels. Safety concerns associated with essential oil use do not generally apply to cosmetic extracts.

Solvent and humectant used to improve texture and ingredient delivery in topical cosmetic formulas. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Volatile solvent used to improve texture, drying time, and penetration in some formulas. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed; the main practical issue is dryness, stinging, or barrier disruption in some users.

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

An ethoxylated glycerin humectant used to retain moisture and improve product texture. The Cosmetic Ingredient Review assessed glycerin ethoxylates including Glycereth-26 for current cosmetic use; available evidence does not identify a pregnancy- or breastfeeding-specific concern from normal topical exposure.

Polymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.

Betaine is a humectant/osmolyte used to support hydration and reduce irritation potential in formulas; it is considered low concern with no known pregnancy or breastfeeding risks in topical cosmetic use.

Sugar-derived humectant used to help bind water and improve skin feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Polyglycerin fatty-acid ester used as an emulsifier and solubilizer. Reviewed cosmetic safety references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

A polyglycerin fatty-acid ester used as an emulsifier, dispersant or emollient. Cosmetic safety reviewers concluded that the assessed family of 274 polyglyceryl fatty acid esters is safe in current practices when formulated to be non-irritating. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Orange peel essential oil used mainly for fragrance. Normal topical cosmetic use has no established pregnancy-specific concern. The practical concerns are oxidation, irritation, sensitisation and, depending on composition and processing, light-related skin reactions.

An exact label variant for lemon peel oil used mainly as a fragrance ingredient. At typical cosmetic concentrations there is no established pregnancy-specific concern. The main issues are oxidation, sensitisation and possible phototoxicity depending on composition, processing and use level.

Bergamot essential oil used mainly for fragrance. No pregnancy-specific hazard is established for normal topical cosmetic exposure. Expressed bergamot oil can be phototoxic unless furocoumarins are controlled, so sun-exposed use should follow the finished product directions and applicable fragrance standards.

A volatile oil from eucalyptus leaves used mainly for fragrance and skin conditioning. Cosmetic safety reviewers concluded that Eucalyptus globulus-derived ingredients are safe in current practices when formulated to be non-sensitising. Essential oils can irritate sensitive skin and should not be swallowed or used undiluted.

Lavender oil is used in cosmetics mainly as a fragrance ingredient. For normal diluted topical cosmetic use, current evidence does not establish a pregnancy-specific concern. This assessment does not cover ingestion, concentrated essential-oil use, or aromatherapy-style exposure. The more relevant practical issues in skincare are irritation or sensitisation in some users, so within this methodology it remains in no known risks.

A grape fruit or seed extract used for skin conditioning and antioxidant support. Cosmetic safety reviewers concluded that the assessed Vitis vinifera-derived ingredients are safe in current practices when formulated to be non-irritating and non-sensitising. Botanical sensitivity remains possible.

A citrus fruit extract used mainly for skin conditioning. Cosmetic safety reviewers concluded that the assessed citrus fruit-derived ingredients are safe in current practices when formulated to be non-irritating and non-sensitising. Fruit extracts are distinct from concentrated peel essential oils, and botanical sensitivity remains possible.

An apple fruit extract used mainly for skin conditioning. Cosmetic safety reviewers concluded that Pyrus malus fruit extract and the other supported apple-derived ingredients are safe in current cosmetic practices of use and concentration. The conclusion does not extend to several separately identified root, stem, callus or oil ingredients for which evidence was insufficient. No pregnancy-specific concern was identified for normal topical use of the fruit extract.

A citrus fruit extract used mainly for skin conditioning. Cosmetic safety reviewers concluded that the assessed citrus fruit-derived ingredients are safe in current practices when formulated to be non-irritating and non-sensitising. Fruit extracts are distinct from concentrated peel essential oils, and botanical sensitivity remains possible.

Botanical skin-conditioning ingredient used in soothing and barrier-support formulas. Reviewed cosmetic safety sources support current cosmetic use when formulated to be non-sensitising, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

A Chinese skullcap root extract used for skin conditioning and antioxidant effects. Cosmetic safety reviewers concluded that the root extract is safe in current practices of use and concentration; this conclusion does not extend to the generic whole-plant or sprout extracts, for which evidence was insufficient. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

A purslane extract used mainly for skin conditioning. Cosmetic safety reviewers concluded that Portulaca oleracea extract is safe in current cosmetic practices when formulated to be non-sensitising. Botanical irritation or allergy remains possible, but no pregnancy-specific concern was identified for normal topical use.