MediCube Deep Vita C Pad by MediCube
MediCube

MediCube Deep Vita C Pad

Toners

Safety score

Pregnancy-focused assessment

Low Risk78/100
Higher concernLower concern

One or more ingredients have a low-risk flag in MamaSkin's current assessment. Review the notes and your own circumstances.

Formula and assessment check

Ingredient safety review updated 22 January 2026. Product formulas can change, so compare the ingredients shown here with the packaging you have.

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Ingredient breakdown

See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.

45

No known risks

3

Low risk

0

Medium risk

0

High risk

Ingredients

Ingredients with a higher risk flag appear first, followed by the rest of the formula.

Gluconolactone

Low Risk

Polyhydroxy acid (PHA) used as a gentle exfoliant/humectant; generally less irritating than AHAs due to lower penetration. Considered safe as used in cosmetics, with no pregnancy-specific contraindications identified at topical cosmetic concentrations.

Sources: PubMed, U.S. National Library of Medicine (NLM)

Dipotassium Glycyrrhizate

Low Risk

A purified glycyrrhizic-acid salt used as a soothing and skin-conditioning ingredient. Cosmetic safety reviewers concluded that dipotassium glycyrrhizate is safe in current cosmetic use and noted poor dermal absorption. MamaSkin nevertheless applies a cautious low-risk classification for consistency with the existing licorice family because high oral glycyrrhizin exposure has pregnancy-related concerns; this is not a topical contraindication.

Sources: CIR: Safety Assessment of Glycyrrhizic Acid and Derivatives https://cir-reports.cir-safety.org/view-attachment/?id=49a63435-8e74-ec11-8943-0022482f06a6

Lactic Acid

Low Risk

Endogenous alpha-hydroxy acid and humectant; at modest cosmetic concentrations (≈5% and below, and generally <10%) topical lactic acid is considered compatible with pregnancy. Main risks are local irritation and increased photosensitivity rather than systemic toxicity or fetal effects.

Sources: PubMed, U.S. National Library of Medicine (NLM); dermatology pregnancy skincare reviews

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Hippophae Rhamnoides Water

No Known Risks

hippophae rhamnoides water is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not a concentrated essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

Sources: CIR ingredient-specific and botanical-family safety assessments; CIR Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng

Water

No Known Risks

Methyl Gluceth-20

No Known Risks

A glucose-derived humectant and conditioning ingredient. Cosmetic safety reviewers concluded that methyl gluceth-20 is safe as used in cosmetics; reviewed skin testing did not indicate sensitisation. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Sources: CIR: Final Report on the Safety Assessment of Methyl Gluceth-10 and Methyl Gluceth-20 https://cir-reports.cir-safety.org/view-attachment?id=fb9dc889-8e74-ec11-8943-0022482f06a6

Methylpropanediol

No Known Risks

Solvent and humectant used to improve texture and ingredient delivery in topical cosmetic formulas. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for alkane diols; EU CosIng / cosmetics regulatory inventory

Niacinamide

No Known Risks

Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Glycereth-26

No Known Risks

An ethoxylated glycerin humectant used to retain moisture and improve product texture. The Cosmetic Ingredient Review assessed glycerin ethoxylates including Glycereth-26 for current cosmetic use; available evidence does not identify a pregnancy- or breastfeeding-specific concern from normal topical exposure.

Sources: CIR: Safety Assessment of Glycerin Ethoxylates https://cir-safety.org/supplementaldoc/safety-assessment-glycerin-ethoxylates-used-cosmetics

Methyl Gluceth-10

No Known Risks

A cosmetic functional ingredient used for conditioning, texture or formula support. Available cosmetic-use information did not identify a reproductive or developmental hazard from normal topical exposure.

Sources: European Commission CosIng ingredient inventory; relevant CIR cosmetic safety assessments and peer-reviewed cosmetic-use literature.

Polyglycerin-3

No Known Risks

A small glycerin polymer used as a humectant and conditioning ingredient. Cosmetic safety reviewers assessed polyglycerin-3 with diglycerin and related polyglycerins and concluded that they are safe in current practices of use and concentration. No pregnancy-specific concern was identified for normal topical use.

Sources: CIR: Safety Assessment of Diglycerin and Polyglycerins as Used in Cosmetics https://www.cir-safety.org/panelbook/safety-assessment-diglycerin-and-polyglycerin-3-6-and-10-used-cosmetics

1,2-Hexanediol

No Known Risks

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

3-O-Ethyl Ascorbic Acid

No Known Risks

A stable ether derivative of vitamin C used as an antioxidant and brightening ingredient. Pregnancy-specific topical studies are limited, but no pregnancy-specific contraindication was identified in the reviewed literature. Published case reports describe allergic contact dermatitis, so local sensitivity remains possible and this classification should not be read as proof that irritation cannot occur.

Sources: CIR: Safety Assessment of Ethers of Ascorbic Acid https://www.cir-safety.org/sites/default/files/ethers_of_ascorbate.pdf; PubMed: 3-O-ethyl-L-ascorbic acid topical delivery https://pubmed.ncbi.nlm.nih.gov/31517290/; PubMed: allergic contact dermatitis case report https://pubmed.ncbi.nlm.nih.gov/24846587/

Ethylhexylglycerin

No Known Risks

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Cymbopogon Martini Oil

No Known Risks

A volatile botanical oil used mainly for fragrance and skin conditioning. The relevant cosmetic concerns are irritation, sensitisation and constituent quality. No pregnancy-specific systemic hazard was identified for normal topical exposure to a compliant finished cosmetic.

Sources: European Commission CosIng ingredient inventory; IFRA ingredient and fragrance-safety resources; relevant CIR botanical safety assessments. No ingredient-specific human pregnancy study of topical cosmetic use was identified.

Cymbopogon Nardus Oil

No Known Risks

Adenosine

No Known Risks

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Butylene Glycol

No Known Risks

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Disodium EDTA

No Known Risks

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Mentha Viridis Extract

No Known Risks

Lactobacillus/Lemon Peel Ferment Extract

No Known Risks

Geraniol

No Known Risks

A floral fragrance ingredient found in several essential oils and also used in manufactured form. It is a recognised contact allergen, but no pregnancy-specific hazard is identified for normal topical cosmetic exposure.

Sources: European Commission: Fragrance allergens labelling https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-products-specific-topics/fragrance-allergens-labelling_en; SCCS fragrance-allergen opinions

Citronellol

No Known Risks

A rose-like fragrance ingredient that occurs naturally in many essential oils and may also be manufactured. Its main cosmetic concern is contact allergy in susceptible users; no pregnancy-specific hazard is identified for normal topical cosmetic exposure.

Sources: European Commission: Fragrance allergens labelling https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-products-specific-topics/fragrance-allergens-labelling_en; SCCS fragrance-allergen opinions

Coptis Japonica Extract

No Known Risks

Cucumis Melo Seed Extract

No Known Risks

Litsea Cubeba Fruit Oil

No Known Risks

Litsea cubeba fruit oil, a citral-rich volatile fragrance oil that may irritate or sensitise susceptible skin. Available cosmetic and fragrance information focuses on irritation, sensitisation and constituent quality. No pregnancy-specific hazard was identified for normal topical exposure to a compliant finished cosmetic.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant ingredient-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

Pelargonium Graveolens Extract

No Known Risks

Allantoin

No Known Risks

Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Panthenol

No Known Risks

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Sodium Hyaluronate

No Known Risks

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Glucose

No Known Risks

Simple sugar used as a humectant and skin-conditioning support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Beta-Glucan

No Known Risks

Film-forming polysaccharide used for soothing and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Linalool

No Known Risks

Linalool is a common fragrance component used at low levels in cosmetics; it is not a pregnancy-specific concern in topical use, but it is a recognised fragrance allergen and may trigger irritation or sensitisation in some people, especially if the product oxidises over time.

Sources: EU/UK cosmetics (fragrance allergen labelling); IFRA; toxicology reviews

Hyaluronic Acid

No Known Risks

High-water-binding humectant used to support hydration at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Glycerin

No Known Risks

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Caprylic/Capric Triglyceride

No Known Risks

Common emollient derived from fatty acids and glycerin. Used to soften skin and improve texture without pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Tocopherol

No Known Risks

Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Cetyl Palmitate

No Known Risks

A waxy fatty-acid ester used as an emollient and texture agent. Cosmetic safety reviewers concluded that cetyl palmitate and the wider alkyl-ester group are safe in current practices of use; finished formulas should be non-irritating. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Sources: CIR: Safety Assessment of Alkyl Esters as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=b34bc38f-8e74-ec11-8943-0022482f06a6

Ubiquinone

No Known Risks

Ubiquinone, also called coenzyme Q10, is an antioxidant and skin-conditioning ingredient. The Cosmetic Ingredient Review concluded that ubiquinone ingredients are safe in current cosmetic use; no pregnancy- or breastfeeding-specific concern is identified for normal topical exposure.

Sources: CIR: Safety Assessment of Ubiquinone Ingredients https://www.cir-safety.org/supplementaldoc/safety-assessment-ubiquinone-ingredients-used-cosmetics-0

Polysorbate 80

No Known Risks

Nonionic emulsifier and solubilizer used to disperse oils in cosmetic formulas. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.

Sources: CIR: Safety Assessment of Polysorbates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Sorbitan Stearate

No Known Risks

This sorbitan fatty-acid ester is an emulsifier that helps oil and water phases remain mixed. The Cosmetic Ingredient Review concluded that sorbitan esters are safe in current cosmetic use; occasional contact reactions remain possible in sensitive users.

Sources: CIR: Safety Assessment of Sorbitan Esters as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-sorbitan-esters-used-cosmetics

Sodium Benzoate

No Known Risks

Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Citric Acid

No Known Risks

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Hydrogenated Lecithin

No Known Risks

Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US)

Palmitoyl Tripeptide-5

No Known Risks

Synthetic signal peptide used in topical cosmetic anti-aging and skin-conditioning formulas. Reviewed cosmetic peptide literature lists palmitoyl tripeptide-5 among topically used matricin-style peptides. No pregnancy- or breastfeeding-specific risk signal was identified for normal topical cosmetic use.

Sources: Schagen SK. Topical Peptide Treatments with Effective Anti-Aging Results. Cosmetics. 2017;4(2):16. doi:10.3390/cosmetics4020016; EU CosIng / INCI cosmetic ingredient references.

Ergothioneine

No Known Risks

A naturally occurring small molecule used for antioxidant, conditioning or cellular-energy support in cosmetics. Creatine and ergothioneine occur in human or dietary biology, and no pregnancy-specific hazard signal was identified for the much smaller exposure expected from normal topical cosmetic use. This classification does not assess concentrated oral supplements.

Sources: European Commission CosIng ingredient inventory; PubMed literature on topical Creatine and Ergothioneine, dermal delivery and cosmetic use; ECHA substance information where available.

Hesperidin

No Known Risks

Palmitoyl Tetrapeptide-10

No Known Risks

palmitoyl tetrapeptide-10 is an amino acid, peptide, protein-related or glycosaminoglycan cosmetic conditioning ingredient. Expected systemic exposure from normal topical use is low, and relevant cosmetic-family assessments did not identify a pregnancy-specific concern. Manufacturing quality and residual allergenic proteins remain relevant where applicable.

Sources: CIR assessments of alpha-amino acids, plant-derived amino acids, proteins and peptides https://www.cir-safety.org/supplementaldoc/safety-assessment-%CE%B1-amino-acids-used-cosmetics; European Commission CosIng

Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.

How to use this assessment

The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.

MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.

Read the full methodology