MediCube One Day Zero Exosome Shot by MediCube
MediCube

MediCube One Day Zero Exosome Shot

Ampoulesserums

Safety score

Pregnancy-focused assessment

Low Risk78/100
Higher concernLower concern

One or more ingredients have a low-risk flag in MamaSkin's current assessment. Review the notes and your own circumstances.

Ingredient safety review updated 9 December 2025.

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Ingredient breakdown

See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.

25

No known risks

2

Low risk

0

Medium risk

0

High risk

Ingredients

Ingredients with a higher risk flag appear first, followed by the rest of the formula.

Betaine Salicylate

Low Risk

Ester form of salicylic acid; hydrolyses to SA, low-strength topical use shows negligible systemic absorption - chemical peels ≥30 % should be avoided.

Sources: PubMed, U.S. National Library of Medicine (NLM), NHS, MotherToBaby (OTIS), UKTIS (BUMPS)

Gluconolactone

Low Risk

Polyhydroxy acid (PHA) used as a gentle exfoliant/humectant; generally less irritating than AHAs due to lower penetration. Considered safe as used in cosmetics, with no pregnancy-specific contraindications identified at topical cosmetic concentrations.

Sources: PubMed, U.S. National Library of Medicine (NLM)

Water

No Known Risks
Show all (27)

Dipropylene Glycol

No Known Risks

Dipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Glycerin

No Known Risks

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Butylene Glycol

No Known Risks

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

1,2-Hexanediol

No Known Risks

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

Niacinamide

No Known Risks

Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Sodium Polyacrylate

No Known Risks

Polymer used for texture and absorbency. Large-molecule ingredient with low systemic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Ethylhexyl Palmitate

No Known Risks

Lightweight emollient ester used to soften skin and improve glide. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Amended Safety Assessment of Alkyl Esters as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Hydrolyzed Sponge

No Known Risks

C12-14 Alketh-12

No Known Risks

Hydrogenated Polydecene

No Known Risks

Synthetic hydrocarbon emollient used to improve slip, cushion and moisture feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for polydecenes/hydrocarbon emollients; EU CosIng / cosmetics regulatory inventory

Ethylhexylglycerin

No Known Risks

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Adenosine

No Known Risks

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Caprylyl/Capryl Glucoside

No Known Risks

This glucose-derived nonionic surfactant or emulsifier is used in cleansers and emulsions. The Cosmetic Ingredient Review concluded that alkyl glucosides are safe in current cosmetic use when formulated to be non-irritating; sensitive skin can still react to surfactants.

Sources: CIR: Safety Assessment of Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=9810a771-8e74-ec11-8943-0022482f06a6

Disodium EDTA

No Known Risks

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Panthenol

No Known Risks

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Calcium Silicate

No Known Risks

Lactobacillus Extracellular Vesicles

No Known Risks

Campsis Grandiflora Flower Extract

No Known Risks

Pueraria Lobata Root Extract

No Known Risks

Pinus Palustris Leaf Extract

No Known Risks

Oenothera Biennis Flower Extract

No Known Risks

Ulmus Davidiana Root Extract

No Known Risks

Sodium Silicate

No Known Risks

Citric Acid

No Known Risks

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.

How to use this assessment

The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.

MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.

Read the full methodology