MediCube Zero Pore SA Clear Capsule Cleansing Foam by MediCube
MediCube

MediCube Zero Pore SA Clear Capsule Cleansing Foam

Face Cleanserscleansers

Safety score

Pregnancy-focused assessment

Low Risk71/100
Higher concernLower concern

One or more ingredients have a low-risk flag in MamaSkin's current assessment. Review the notes and your own circumstances.

Formula and assessment check

Ingredient safety review updated 9 December 2025. Product formulas can change, so compare the ingredients shown here with the packaging you have.

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Ingredient breakdown

See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.

37

No known risks

5

Low risk

0

Medium risk

0

High risk

Ingredients

Ingredients with a higher risk flag appear first, followed by the rest of the formula.

Parfum

Low Risk

Umbrella term for an undisclosed fragrance blend. It’s not usually a pregnancy-specific concern at normal cosmetic use levels, but the exact components and concentrations aren’t fully disclosed on the label, so we score it more conservatively. If you prefer maximum transparency (or you’re sensitive to fragrance compounds), choose fragrance-free/unscented products.

Sources: SCCS: Fragrance allergens in cosmetic products https://health.ec.europa.eu/latest-updates/sccs-new-opinion-fragrance-allergens-cosmetic-products-2012-07-31_en

Salicylic Acid 0.45%

Low Risk

Salicylic acid is a beta-hydroxy acid used for exfoliation and as a preservative. Exposure depends on concentration, product category, treated area, frequency, skin condition and inhalation or oral potential. Current SCCS assessments support specified cosmetic uses and restrictions; ordinary limited-area low-strength topical use is not equivalent to a professional peel, large-area leave-on treatment or oral salicylate exposure. MamaSkin retains Low Risk with those route and exposure qualifications.

Sources: SCCS/1646/22: Final Opinion on Salicylic Acid https://health.ec.europa.eu/latest-updates/sccs-final-opinion-salicylic-acid-2023-06-09_en; SCCS follow-up on children's exposure https://health.ec.europa.eu/publications/sccs-opinion-salicylic-acid-cas-no-69-72-7-ec-no-200-712-3-childrens-exposure_en

Gluconolactone

Low Risk

Polyhydroxy acid (PHA) used as a gentle exfoliant/humectant; generally less irritating than AHAs due to lower penetration. Considered safe as used in cosmetics, with no pregnancy-specific contraindications identified at topical cosmetic concentrations.

Sources: MotherToBaby: Topical acne treatments in pregnancy and breastfeeding https://www.ncbi.nlm.nih.gov/books/NBK582985/

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Mandelic Acid

Low Risk

Aromatic alpha-hydroxy acid with larger molecular size than glycolic; penetrates more slowly and is less irritating. Topical use in cosmetic-strength peels and serums is generally regarded as low risk in pregnancy, with irritation and photosensitivity as the main concerns when overused.

Sources: MotherToBaby: Topical acne treatments in pregnancy and breastfeeding https://www.ncbi.nlm.nih.gov/books/NBK582985/

Salix Alba Bark Extract

Low Risk

Willow bark is a salicin-containing botanical material. Its composition and delivered salicylate exposure vary by species, plant part, extraction method and concentration, so a cosmetic extract should not be treated as dose-equivalent to a stated concentration of salicylic acid. MamaSkin retains Low Risk as a conservative family policy for ordinary topical cosmetic use; this does not cover oral willow-bark medicines, concentrated preparations, large-area use or salicylate allergy.

Sources: EMA/HMPC: Salicis cortex assessment and monograph materials https://www.ema.europa.eu/en/medicines/herbal/salicis-cortex; CIR 2026 review materials for Salix alba-derived cosmetic ingredients https://www.cir-safety.org/panelbook/safety-assessment-salix-alba-willow-derived-ingredients-used-cosmetics

Water

No Known Risks

Glycerin

No Known Risks

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Sodium Cocoyl Glycinate

No Known Risks

An amino-acid-derived surfactant or conditioning ingredient. Cosmetic safety reviewers concluded that amino acid alkyl amides are safe in current cosmetic practices when formulated to be non-irritating. Manufacturing and formulation should control nitrosamine formation where relevant.

Sources: CIR: Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-amino-acid-alkyl-amides-used-cosmetics-0

Sodium Lauroyl Glutamate

No Known Risks

An amino-acid-derived surfactant or conditioning ingredient. Cosmetic safety reviewers concluded that amino acid alkyl amides are safe in current cosmetic practices when formulated to be non-irritating. Manufacturing and formulation should control nitrosamine formation where relevant.

Sources: CIR: Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-amino-acid-alkyl-amides-used-cosmetics-0

Lauryl Hydroxysultaine

No Known Risks

An amphoteric surfactant used for mild cleansing and foam support. Cosmetic safety reviewers concluded that sultaines, including lauryl hydroxysultaine, are safe in current practices when formulated to be non-irritating and when impurities are controlled. Rare contact allergy remains possible.

Sources: CIR: Safety Assessment of Sultaines as Used in Cosmetics, IJT 43(Suppl. 1), 2024; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Coco-Glucoside

No Known Risks

This glucose-derived nonionic surfactant or emulsifier is used in cleansers and emulsions. The Cosmetic Ingredient Review concluded that alkyl glucosides are safe in current cosmetic use when formulated to be non-irritating; sensitive skin can still react to surfactants.

Sources: CIR: Safety Assessment of Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=9810a771-8e74-ec11-8943-0022482f06a6

Decyl Glucoside

No Known Risks

Mild nonionic surfactant used in cleansers and emulsions. Reviewed cosmetic ingredient references support normal topical rinse-off and leave-on use, with no pregnancy- or breastfeeding-specific concern identified; sensitive skin may still react to surfactants.

Sources: CIR: Safety Assessment of Alkyl Glucosides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

1,2-Hexanediol

No Known Risks

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

Sodium Chloride

No Known Risks

Sodium chloride is used to adjust viscosity and texture in formulations; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks.

Sources: CIR; EU/UK Cosmetics Regulation

Caprylyl Glycol

No Known Risks

Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Hydroxypropyl Starch Phosphate

No Known Risks

A modified starch used mainly to thicken and stabilize cosmetic formulas. Cosmetic safety reviewers concluded that starch phosphates, including hydroxypropyl starch phosphate, are safe in current cosmetic use. No pregnancy- or breastfeeding-specific concern is identified for normal topical exposure.

Sources: CIR: Safety Assessment of Starch Phosphates https://cir-safety.org/sites/default/files/FR_StarchPhosphates_092022.pdf

Silica

No Known Risks

Mineral absorbent and texture aid used to mattify and improve slip. Reviewed cosmetic safety sources support normal topical cosmetic use; this assessment does not cover deliberate inhalation of loose powder.

Sources: CIR: Safety Assessment of Silica and Silicates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Acrylates/C10-30 Alkyl Acrylate Crosspolymer

No Known Risks

Polymer thickener and stabiliser used in creams and sunscreens. Low systemic exposure expected.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Citric Acid

No Known Risks

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Polyquaternium-67

No Known Risks

A numbered cationic polymer used for hair conditioning, antistatic effects, film formation or formula texture. The Polyquaternium number identifies a distinct polymer, so evidence from one number is not treated as proof for every other number. For this ingredient, no pregnancy, reproductive or breastfeeding hazard signal was identified in the cosmetic-use and substance information reviewed. Its polymeric size makes meaningful absorption through intact skin unlikely; local irritation and control of residual monomers remain formulation-quality considerations.

Sources: European Commission CosIng ingredient inventory; CIR safety assessments and December 2025 Quick Reference Table for structurally and functionally related polyquaternium cosmetic polymers https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf; publicly available supplier safety data and ECHA substance information where available for the named polymer. No ingredient-specific pregnancy studies were identified.

Dextrin

No Known Risks

Starch-derived polysaccharide used as a binder, film former and texture support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for polysaccharides/starch-derived ingredients; EU CosIng / cosmetics regulatory inventory

Zea Mays Starch

No Known Risks

Corn starch, a plant-derived polysaccharide used to absorb moisture, reduce greasiness and improve texture. Cosmetic safety reviewers concluded that ingredients derived from Zea mays, including corn starch, are safe in current cosmetic use. No pregnancy-specific concern is identified for normal topical exposure; avoid deliberately inhaling loose powder.

Sources: CIR ingredient review: Zea mays (Corn) Starch https://www.cir-safety.org/ingredient/zea-mays-corn-starch

Microcrystalline Cellulose

No Known Risks

This cellulose or modified-cellulose polymer is used as a thickener, film former or stabilizer. Cosmetic Ingredient Review data indicate that cellulose polymers do not appreciably penetrate skin and are safe in current cosmetic use, with at most minimal irritation reported.

Sources: CIR: Amended Safety Assessment of Cellulose and Related Polymers as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=2e65c18f-8c74-ec11-8943-0022482f06a6

Mannitol

No Known Risks

This sugar or sugar alcohol is used as a humectant and skin-conditioning ingredient. Cosmetic Ingredient Review assessments support these saccharides in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.

Sources: CIR: Safety Assessment of Monosaccharides Disaccharides and Related Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-monosaccharides-disaccharides-and-related-ingredients-used-cosmeti

Disodium EDTA

No Known Risks

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Sucrose

No Known Risks

This sugar or sugar alcohol is used as a humectant and skin-conditioning ingredient. Cosmetic Ingredient Review assessments support these saccharides in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.

Sources: CIR: Safety Assessment of Monosaccharides Disaccharides and Related Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-monosaccharides-disaccharides-and-related-ingredients-used-cosmeti

Gardenia Taitensis Callus Extract

No Known Risks

Sodium Acetate

No Known Risks

A small organic acid, salt or ester used as a solvent, pH adjuster or formula aid. Cosmetic safety reviewers concluded that acetic acid and the assessed related simple alcohols and esters are safe in current practices.

Sources: CIR: Acetic Acid and related simple alcohols and esters, IJT 31(Suppl. 1), 2012; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Ultramarines

No Known Risks

Pigment used to add blue/violet tones in makeup. In typical topical use it has very low dermal absorption and is generally considered acceptable in pregnancy and breastfeeding. If you prefer a cautious approach, avoid inhaling loose powders or sprays.

Sources: General cosmetic ingredient safety references for pigments; exposure route considerations for powders/sprays.

Tocopheryl Acetate

No Known Risks

Tocopheryl acetate (vitamin E derivative) is used as an antioxidant and skin-conditioning ingredient; it is considered low concern in topical use with no known pregnancy or breastfeeding risks at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Isopropyl Alcohol

No Known Risks

A volatile solvent used to improve drying and dissolve other ingredients. Cosmetic safety reviewers concluded that isopropyl alcohol is safe in current cosmetic practices. The main practical concern is local dryness, stinging or barrier irritation rather than a pregnancy-specific hazard.

Sources: CIR: Safety Assessment of Acetic Acid and Related Simple Alcohols and Esters, IJT 31(Suppl. 1), 2012; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Butylene Glycol

No Known Risks

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Melaleuca Viminalis Extract

No Known Risks

Pyrus Malus Flower Extract

No Known Risks

Camellia Sinensis Leaf Extract

No Known Risks

Camellia sinensis (green tea) leaf extract is used as an antioxidant botanical; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks, though rare sensitivities are possible.

Sources: CIR; EU/UK Cosmetics Regulation

Dioscorea Villosa Root Extract

No Known Risks

Coffea Arabica Seed Extract

No Known Risks

A fruit, seed or food-plant extract used for skin conditioning and antioxidant support. No pregnancy-specific signal was identified for the low topical exposure expected from a finished cosmetic. Direct pregnancy studies are generally unavailable, and botanical allergy remains possible.

Sources: European Commission CosIng ingredient inventory; CIR botanical safety framework and relevant fruit-derived ingredient assessments; peer-reviewed cosmetic and phytochemical literature for the named plants.

Pueraria Lobata Root Extract

No Known Risks

Kudzu root extract is a botanical skin-conditioning ingredient that may contain isoflavones including puerarin, daidzin and daidzein. Oral supplement exposure is not equivalent to the small amount used topically in a finished cosmetic. No evidence establishing a pregnancy or breastfeeding hazard from normal topical cosmetic use was identified.

Sources: PubMed: Chemical constituents of Pueraria lobata root extracts, including puerarin and isoflavones https://pubmed.ncbi.nlm.nih.gov/41900064/; European Commission CosIng ingredient inventory. No ingredient-specific topical pregnancy studies were identified.

Pinus Pinaster Leaf Extract

No Known Risks

pinus pinaster leaf extract is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not a concentrated essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

Sources: CIR ingredient-specific and botanical-family safety assessments; CIR Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng

Oenothera Biennis Flower Extract

No Known Risks

An evening-primrose flower extract used for skin conditioning. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant ingredient-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

Ulmus Davidiana Root Extract

No Known Risks

A Japanese elm root extract used as a skin-conditioning botanical. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant ingredient-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

Mentha Citrata Leaf Extract

No Known Risks

Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.

How to use this assessment

The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.

MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.

Read the full methodology