Safety score
Pregnancy-focused assessment
One or more ingredients have a low-risk flag in MamaSkin's current assessment. Review the notes and your own circumstances.
Formula and assessment check
Ingredient safety review updated 23 November 2025. Product formulas can change, so compare the ingredients shown here with the packaging you have.
Report a formula mismatchMamaSkin assessment · 23 November 2025
MamaSkin currently classifies Naturium Niacinamide Serum 12% Plus Zinc 2% as Low risk, with a stored score of 75/100. This is a precautionary classification, not an unqualified pregnancy-safe recommendation. Read the ingredient context and any manual-review explanation below.
The recorded formula includes 2 ingredient entries with risk flags: Dimethicone (Low risk), Phenoxyethanol (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail.
16 of 16 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.
14
No known risks
2
Low risk
0
Medium risk
0
High risk
Ingredients with a higher risk flag appear first, followed by the rest of the formula.
Phenoxyethanol is a preservative permitted in EU cosmetics up to 1.0%. The SCCS concluded it is safe for cosmetic use at that level, including when considering higher cosmetic exposure scenarios in infants and young children. Main practical concern is irritation/stinging on very sensitive or compromised skin rather than a pregnancy- or breastfeeding-specific risk.
Sources: SCCS/1575/16: Phenoxyethanol opinion https://health.ec.europa.eu/publications/phenoxyethanol_en
Dimethicone is a silicone polymer used as a skin protectant and slip/conditioning agent. It is considered inert with minimal dermal absorption; the main practical issues are cosmetic (feel) and occasional irritation in very sensitive users. It is not a pregnancy-specific concern in topical cosmetic use.
Sources: CIR: Amended Safety Assessment of Dimethicone, Methicone, and Substituted-Methicone Polymers as Used in Cosmetics https://cir-safety.org/supplementaldoc/amended-safety-assessment-dimethicone-methicone-and-substituted-methicone-polymers-2
Water (aqua) is the purified solvent used as the base of many cosmetics. MamaSkin classifies plain water as No known risks for normal topical use. Cosmetic water quality must be controlled to prevent contamination; this entry does not cover botanical waters or establish the safety of the finished formula.
Sources: Personal Care Products Council, CosmeticsInfo: Water https://www.cosmeticsinfo.org/ingredient/water/; FDA: Cosmetic Ingredient Names (Water/Aqua identity) https://www.fda.gov/cosmetics/cosmetics-labeling/cosmetic-ingredient-names
Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
A zinc salt of pyrrolidone carboxylic acid used for skin conditioning, oil-control and antimicrobial support. Cosmetic safety reviewers concluded that the assessed zinc salts are safe in current cosmetic practices of use and concentration when formulated to be non-irritating. Zinc is an essential nutrient, but this entry assesses the low topical exposure from a finished cosmetic rather than supplements or medicinal doses. No pregnancy-specific topical concern was identified.
Sources: CIR: Safety Assessment of Zinc Salts as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-zinc-salts-used-cosmetics-1; CIR 146th Expert Panel Meeting final report record https://www.cir-safety.org/meeting/146th-cir-expert-panel-meeting
polyacrylate crosspolymer-11 is a cosmetic polymer, film former or high-molecular-weight texture aid. Systemic dermal absorption is expected to be limited when manufactured with appropriate residual-monomer and impurity controls. No pregnancy-specific concern was identified for normal cosmetic use; avoid inhaling airborne powder or spray droplets.
Sources: CIR polymer safety assessments and Quick Reference Table https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025; European Commission CosIng ingredient inventory
Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.
Sources: European cosmetics regulatory framework
Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
A high-molecular-weight polymer used for hydration and formula texture. Cosmetic safety reviewers concluded that glyceryl polyacrylate is safe in current practices. Absorption of the intact polymer is expected to be limited, and residual monomers should be controlled.
Sources: CIR: Glyceryl Polyacrylate final assessment, June 2022; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
Tocopheryl acetate (vitamin E derivative) is used as an antioxidant and skin-conditioning ingredient; it is considered low concern in topical use with no known pregnancy or breastfeeding risks at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Solvent and humectant used to improve texture and ingredient solubility in topical cosmetics. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.
Sources: CIR cosmetic ingredient safety references for alkane diols/glycols; EU CosIng / cosmetics regulatory inventory
pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.
16 of 16 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.
No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.
The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.
MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.
