Prequel Gleanser Non-Drying Glycerin Cleanser For Face And Body by Prequel
Prequel

Prequel Gleanser Non-Drying Glycerin Cleanser For Face And Body

Face Cleanserscleansers

Safety score

Pregnancy-focused assessment

Low Risk76/100
Higher concernLower concern

One or more ingredients have a low-risk flag in MamaSkin's current assessment. Review the notes and your own circumstances.

Formula and assessment check

Ingredient safety review updated 24 November 2025. Product formulas can change, so compare the ingredients shown here with the packaging you have.

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Ingredient breakdown

See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.

19

No known risks

1

Low risk

0

Medium risk

0

High risk

Ingredients

Ingredients with a higher risk flag appear first, followed by the rest of the formula.

Phenoxyethanol

Low Risk

Phenoxyethanol is a preservative permitted in EU cosmetics up to 1.0%. The SCCS concluded it is safe for cosmetic use at that level, including when considering higher cosmetic exposure scenarios in infants and young children. Main practical concern is irritation/stinging on very sensitive or compromised skin rather than a pregnancy- or breastfeeding-specific risk.

Sources: SCCS/1575/16: Phenoxyethanol opinion https://health.ec.europa.eu/publications/phenoxyethanol_en

Glycerin 50%

No Known Risks

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Water

No Known Risks
Show all (20)

Cocamidopropyl Betaine

No Known Risks

Mild amphoteric surfactant used in cleansers and shampoos to boost foam and reduce harshness. Reviewed cosmetic safety sources support present cosmetic use, with no pregnancy- or breastfeeding-specific topical signal identified; the main practical caveat is irritation or allergy in some users, sometimes linked to sensitising impurities.

Sources: CIR: Safety Assessment of Cocamidopropyl Betaine and Related Amidopropyl Betaines as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Disodium Cocoamphodiacetate

No Known Risks

A mild amphoteric cleansing surfactant. Cosmetic safety reviewers concluded that disodium cocoamphodiacetate is safe as used; the original conclusion was reaffirmed on re-review, while the current group reassessment proposes non-sensitising formulation controls. Impurities may contribute to occasional irritation or allergy.

Sources: CIR: Final Report on Cocoamphoacetate and Related Ingredients, J Am Coll Toxicol 9(2):121-142, 1990; current CIR reassessment and original-report history https://cir-reports.cir-safety.org/view-attachment?id=650ade8c-833f-a428-bb22-fa7740c7229b

Sodium Chloride

No Known Risks

Sodium chloride is used to adjust viscosity and texture in formulations; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks.

Sources: CIR; EU/UK Cosmetics Regulation

Inulin

No Known Risks

A plant-derived polysaccharide used for conditioning and formula texture. Cosmetic safety reviewers included inulin in the plant polysaccharide gums group and concluded that the group is safe in current practices of use and concentration. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Sources: CIR: Safety Assessment of Plant Polysaccharide Gums as Used in Cosmetics https://www.cir-safety.org/sites/default/files/plpogu092014slr.pdf

Dihydroxypropyl Arginine Hcl

No Known Risks

Aloe Barbadensis Leaf Juice

No Known Risks

Aloe barbadensis leaf juice is commonly used for soothing and hydration; topical use is considered low concern with no known pregnancy or breastfeeding risks, although rare sensitivities can occur.

Sources: CIR; EU/UK Cosmetics Regulation

Avena Sativa Kernel Flour

No Known Risks

Finely milled oat kernel material used for soothing, absorbency and skin conditioning. Cosmetic safety reviewers concluded that Avena sativa kernel flour is safe in current practices when formulated to be non-sensitising. People with oat sensitivity may still react, and loose powder should not be deliberately inhaled.

Sources: CIR: December 2025 Quick Reference Table, Avena Sativa (Oat) Kernel Flour conclusion, IJT 38(Suppl. 3), 2019 https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Glyceryl Glucoside

No Known Risks

A sugar-derived humectant or starch hydrolysate used to retain moisture and support formula texture. Cosmetic safety reviewers concluded that the assessed saccharide humectants and hydrogenated starch hydrolysate are safe in current practices. Dermal absorption of larger carbohydrate materials is expected to be limited.

Sources: CIR: Saccharide Humectants safety assessment; Hydrogenated Starch Hydrolysate final report, September 2015; CIR December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Polyquaternium-10

No Known Risks

A large cationic cellulose polymer used to condition hair and improve product texture. Cosmetic safety reviewers concluded that Polyquaternium-10 is safe in current cosmetic use; human testing did not indicate irritation or sensitization at reviewed concentrations. No pregnancy-specific concern is identified for normal topical exposure.

Sources: CIR: Safety Assessment of Polyquaternium-10, cited in the CIR Quick Reference Table https://www.cir-safety.org/sites/default/files/safe-092017posted122017.pdf

Citric Acid

No Known Risks

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Ethylhexylglycerin

No Known Risks

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Hydroxyethylcellulose

No Known Risks

Cellulose-derived thickener used to build viscosity and improve texture. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR Quick Reference Table / ingredient status (Hydroxyethylcellulose, Final Report 03/2009); EU CosIng / cosmetics regulatory inventory

Tetrasodium Glutamate Diacetate

No Known Risks

Chelating agent used to bind trace metals and improve formula stability. CIR concluded it is safe as used in cosmetics; normal topical use is not associated with a pregnancy- or breastfeeding-specific topical signal in the material reviewed.

Sources: CIR: Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Lecithin

No Known Risks

Emulsifier and skin-conditioning ingredient composed of phospholipids. Not associated with pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US)

Xanthan Gum

No Known Risks

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Sources: European cosmetics regulatory framework

Pentylene Glycol

No Known Risks

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Sodium Hydroxide

No Known Risks

pH adjuster used in very small quantities to balance formulations. Not associated with pregnancy-specific concerns.

Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework

Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.

How to use this assessment

The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.

MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.

Read the full methodology