Prequel
Prequel Gleanser Non-Drying Glycerin Cleanser For Face And Body
Low risk76/100
Prequel
Reactive Skin Solutions 5% Ectoin Cream
Facial Treatments
No higher-risk flags in the assessed ingredients. This is a screening result, not a guarantee of pregnancy safety.
19 of 19 ingredients rated
Is it suitable during pregnancy?
MamaSkin rates the recorded formula for Prequel Reactive Skin Solutions 5% Ectoin Cream as No known risks (99/100). This screening result is not a guarantee of safety for every pregnancy.
Why this rating?
No higher-risk ingredient flags are shown in the assessed entries. Ingredients without a matched rating are marked Not assessed, not No known risks.
19 of 19 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
How we assess productsIngredient breakdown
The recorded formula, with evidence behind each rating. Unmatched ingredients are marked Not assessed in grey.
Ingredient ratings and evidence
Higher-risk flags first. Open an ingredient for evidence.
Water
No known risks
Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en
Cetearyl Alcohol
No known risks
Fatty alcohol used as an emollient and thickener. Not the same as drying alcohols and not associated with pregnancy-specific concerns.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Ectoin
No known risks
A small natural osmolyte used to support hydration and the skin barrier. A systematic review of topical ectoin formulations in adults and children reported very good tolerability. Pregnancy-specific topical studies were not identified, but no reproductive or pregnancy-specific signal was found for normal cosmetic exposure.
Sources: PubMed: Topical Ectoine Application in Children and Adults, systematic review https://pubmed.ncbi.nlm.nih.gov/35038127/
Urea
No known risks
A naturally occurring component of skin moisturizing factors, used in cosmetics as a humectant and at higher concentrations as a keratolytic. Ordinary cosmetic use does not identify a pregnancy-specific concern. Higher-strength products may sting or irritate damaged skin. Urea itself is distinct from formaldehyde-releasing preservatives such as imidazolidinyl urea and diazolidinyl urea.
Sources: CIR ingredient record: Urea https://cir-safety.org/ingredient/urea; EU CosIng cosmetic ingredient inventory: Urea
Cetearyl Isononanoate
No known risks
A fatty-acid ester used mainly for emollience, slip, cleansing or formula texture. Cosmetic safety reviewers concluded that these named esters are safe in current cosmetic practices, with non-irritating formulation conditions where specified.
Sources: CIR: Glycol Stearate, Ethylhexyl Olivate, Cetearyl Isononanoate, Heptyl Undecylenate, Isostearyl Neopentanoate and Octyldodecyl Myristate conclusions; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
Show all 19 ingredients
Glycerin
No known risks
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Simmondsia Chinensis Seed Oil
No known risks
Plant-derived emollient oil used to soften skin and improve formula feel. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Final Report on the Safety Assessment of Simmondsia Chinensis (Jojoba) Seed Oil and related jojoba-derived ingredients; EU CosIng / cosmetics regulatory inventory
Pentylene Glycol
No known risks
Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Hydrogenated Polydecene
No known risks
Synthetic hydrocarbon emollient used to improve slip, cushion and moisture feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.
Sources: CIR cosmetic ingredient safety references for polydecenes/hydrocarbon emollients; EU CosIng / cosmetics regulatory inventory
Hydroxyethyl Urea
No known risks
A humectant that helps skin and hair retain water. Cosmetic safety reviewers concluded that hydroxyethyl urea is safe in current cosmetic use when formulated to be non-irritating; reproductive and developmental data reviewed for the assessment did not identify a pregnancy-specific concern from normal topical exposure.
Sources: CIR: Safety Assessment of Hydroxyethyl Urea https://www.cir-safety.org/supplementaldoc/safety-assessment-hydroxyethyl-urea-used-cosmetics-0
Triacetin
No known risks
triacetin is a cosmetic emollient, ester or lipid-derived formulation aid. Related safety assessments support normal cosmetic use, with irritation and penetration-enhancement qualifications retained where relevant. No pregnancy-specific concern was identified for ordinary topical exposure.
Sources: CIR safety assessments of polyglyceryl fatty acid esters, propylene glycol esters, saccharide esters and related cosmetic esters https://www.cir-safety.org/sites/default/files/PGlyFE092016FR.pdf; European Commission CosIng
Panthenol
No known risks
Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Lecithin
No known risks
Emulsifier and skin-conditioning ingredient composed of phospholipids. Not associated with pregnancy-specific concerns.
Sources: Cosmetic Ingredient Review (US)
Allantoin
No known risks
Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Sodium Cetearyl Sulfate
No known risks
An anionic surfactant used for cleansing and emulsification. Cosmetic safety reviewers concluded that the assessed alkyl sulfates, including sodium cetearyl sulfate, are safe in current cosmetic practices. Irritation depends mainly on concentration, formula and contact time.
Sources: CIR: Safety Assessment of Alkyl Sulfates as Used in Cosmetics, IJT 29(Suppl. 2), 2010; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
Xanthan Gum
No known risks
Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.
Sources: European cosmetics regulatory framework
Cetearyl Glucoside
No known risks
Sugar-based emulsifier used to stabilise creams and lotions. Reviewed cosmetic safety sources support topical cosmetic use; the relevant practical caveat is formulation irritation potential rather than a pregnancy-specific concern.
Sources: CIR: Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Sodium Lactate
No known risks
Humectant and buffer that also forms part of the skin's natural moisturising factor. Reviewed cosmetic safety sources support topical cosmetic use; irritation and sun-sensitivity considerations relate more to formula context than to pregnancy-specific risk.
Sources: CIR: Safety Assessment of Alpha Hydroxy Acids as Used in Cosmetics; CIR: PCA and Its Salts as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Ethylhexylglycerin
No known risks
Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Full recorded ingredient list
Water, Cetearyl Alcohol, Ectoin, Urea, Cetearyl Isononanoate, Glycerin, Simmondsia Chinensis Seed Oil, Pentylene Glycol, Hydrogenated Polydecene, Hydroxyethyl Urea, Triacetin, Panthenol, Lecithin, Allantoin, Sodium Cetearyl Sulfate, Xanthan Gum, Cetearyl Glucoside, Sodium Lactate, Ethylhexylglycerin
Ingredient ratings refreshed 13 October 2026. Formulas vary by market and can change. Always compare with your packaging.
Questions about this assessment
Why does Prequel Reactive Skin Solutions 5% Ectoin Cream have a No known risks rating?
No higher-risk ingredient flags are shown in the assessed entries. Ingredients without a matched rating are marked Not assessed, not No known risks. The product score is a stored assessment, not a clinical safety guarantee.
Does a barrier-care product name establish pregnancy suitability?
No. This recorded formula contains Panthenol or Madecassoside, but a barrier-care claim does not establish the assessment of all its other ingredients. Read the individual ingredient evidence and any manual-review explanation, and compare the recorded list with your packaging.
Has every ingredient in Prequel Reactive Skin Solutions 5% Ectoin Cream been assessed?
19 of 19 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
Does this assessment apply to my Prequel Reactive Skin Solutions 5% Ectoin Cream?
Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.
Does this pregnancy assessment also establish breastfeeding suitability?
No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.
