Anua
Anua Heartleaf Quercetinol Pore Deep Cleansing Foam
Low risk78/100
Is it suitable during pregnancy?
MamaSkin rates the recorded formula for Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum as Low risk (78/100). Review the ingredient context and any manual-review explanation before deciding.
Why this rating?
The recorded formula includes 3 ingredient entries with risk flags: Azelaic Acid (Low risk), Betaine Salicylate (Low risk), Dipotassium Glycyrrhizate (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail.
35 of 35 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
How we assess productsIngredient breakdown
The recorded formula, with evidence behind each rating. Unmatched ingredients are marked Not assessed in grey.
Ingredient ratings and evidence
Higher-risk flags first. Open an ingredient for evidence.
Azelaic Acid
Low risk
Azelaic acid is used topically for acne and pigmentation. MotherToBaby reports that ACOG lists OTC azelaic acid among ingredients that can be used during pregnancy if needed. Product information for 20% azelaic acid states that adequate controlled pregnancy studies are lacking, reports reassuring animal data and estimates about 3.6% absorption after a single topical dose. MamaSkin retains Low Risk while avoiding a categorical “pregnancy-safe” claim.
Sources: MotherToBaby: Topical Acne Treatments https://www.ncbi.nlm.nih.gov/books/NBK582985/, Skinoren 20% cream product information https://www.medicines.org.uk/emc/product/285/smpc
Betaine Salicylate
Low risk
Ester form of salicylic acid; hydrolyses to SA, low-strength topical use shows negligible systemic absorption - chemical peels ≥30 % should be avoided.
Sources: MotherToBaby: Topical acne treatments including salicylic acid https://www.ncbi.nlm.nih.gov/books/NBK582985/
Dipotassium Glycyrrhizate
Low risk
A purified glycyrrhizic-acid salt used as a soothing and skin-conditioning ingredient. Cosmetic safety reviewers concluded that dipotassium glycyrrhizate is safe in current cosmetic use and noted poor dermal absorption. MamaSkin nevertheless applies a cautious low-risk classification for consistency with the existing licorice family because high oral glycyrrhizin exposure has pregnancy-related concerns; this is not a topical contraindication.
Sources: CIR: Safety Assessment of Glycyrrhizic Acid and Derivatives https://cir-reports.cir-safety.org/view-attachment/?id=49a63435-8e74-ec11-8943-0022482f06a6
Water
No known risks
Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en
Propylene Glycol
No known risks
Propylene glycol is a common solvent and humectant with a long history of use; it is not considered a pregnancy or breastfeeding concern in topical cosmetics, though some individuals may experience irritation in leave-on products.
Sources: CIR; EU/UK Cosmetics Regulation
Show all 35 ingredients
Sodium Hydroxide
No known risks
pH adjuster used in very small quantities to balance formulations. Not associated with pregnancy-specific concerns.
Sources: Scientific Committee on Consumer Safety (EU); European cosmetics regulatory framework
Dipropylene Glycol
No known risks
Dipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
1,2-Hexanediol
No known risks
1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.
Sources: CIR; EU/UK Cosmetics Regulation
Panthenol
No known risks
Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Hydroxyethylcellulose
No known risks
Cellulose-derived thickener used to build viscosity and improve texture. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR Quick Reference Table / ingredient status (Hydroxyethylcellulose, Final Report 03/2009); EU CosIng / cosmetics regulatory inventory
Glycerin
No known risks
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Biosaccharide Gum-1
No known risks
Microbial polysaccharide used for film forming, soothing, and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Ethylhexylglycerin
No known risks
Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Allantoin
No known risks
Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Melia Azadirachta Leaf Extract
No known risks
Neem leaf extract is used topically for skin conditioning and antimicrobial support. Reproductive concerns reported for concentrated neem seed preparations, intrauterine exposure, or high oral doses do not establish a hazard from normal topical cosmetic exposure to a leaf extract.
Sources: PubMed: oral purified neem seed extracts in primates https://pubmed.ncbi.nlm.nih.gov/8773426/; PubMed: intrauterine neem oil in primates https://pubmed.ncbi.nlm.nih.gov/8143455/; European Commission CosIng ingredient inventory. No human pregnancy study of normal topical cosmetic leaf-extract use was identified.
Camellia Sinensis Leaf Water
No known risks
A water derived from green tea leaves and used for skin conditioning. Cosmetic safety reviewers concluded that Camellia sinensis leaf water is safe in current practices when formulated to be non-sensitising.
Sources: CIR: Camellia Sinensis Leaf Water conclusion, IJT 38(Suppl. 3), 2019; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf
Sodium Hyaluronate
No known risks
Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Melia Azadirachta Flower Extract
No known risks
Neem flower extract is used as a botanical skin-conditioning ingredient. A high-dose oral rat study altered the oestrous cycle and ovulation but did not show anti-implantation, abortifacient, or teratogenic effects. That oral dose does not establish a hazard from normal topical cosmetic exposure.
Sources: PubMed: high-dose oral neem flower extract reproductive study in rats https://pubmed.ncbi.nlm.nih.gov/19357745/; European Commission CosIng ingredient inventory. No human pregnancy study of normal topical cosmetic use was identified.
Niacinamide
No known risks
Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Aloe Barbadensis Leaf Juice
No known risks
Aloe barbadensis leaf juice is commonly used for soothing and hydration; topical use is considered low concern with no known pregnancy or breastfeeding risks, although rare sensitivities can occur.
Sources: CIR; EU/UK Cosmetics Regulation
Beta-Glucan
No known risks
Film-forming polysaccharide used for soothing and hydration support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Microbial Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Centella Asiatica Extract
No known risks
Botanical skin-conditioning ingredient used in soothing and barrier-support formulas. Reviewed cosmetic safety sources support current cosmetic use when formulated to be non-sensitising, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Centella asiatica-derived Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Centella Asiatica Leaf Extract
No known risks
A leaf extract used in soothing and skin-conditioning formulas. Cosmetic safety reviewers concluded that Centella asiatica leaf extract is safe at current cosmetic exposure when products are formulated to be non-sensitising. The assessment considered systemic and reproductive findings reported at substantially higher oral exposures; these did not establish a pregnancy-specific concern for ordinary topical cosmetic use. Centella constituents can still cause contact sensitivity in some people.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
Centella Asiatica Root Extract
No known risks
A botanical extract or plant water used for conditioning, soothing or antioxidant support. Direct pregnancy studies of this exact cosmetic material were not identified, but no reproductive or developmental hazard was identified for normal topical exposure. Oral herbal or medicinal use is outside this classification.
Sources: European Commission CosIng; CIR botanical safety framework and relevant plant-family assessments; no ingredient-specific human pregnancy study of normal topical cosmetic use was identified.
Madecassoside
No known risks
A triterpene glycoside associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical madecassoside is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but noted that madecassoside and related triterpenes may contribute to sensitisation, so products should be formulated to avoid sensitising concentrations. No pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
Asiaticoside
No known risks
A triterpene glycoside associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical asiaticoside is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but noted that asiaticoside and related triterpenes may contribute to sensitisation. No pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
Asiatic Acid
No known risks
A triterpene associated with Centella asiatica and used in skin-conditioning formulas. Pregnancy-specific evidence for isolated topical asiatic acid is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but identified asiatic acid and related constituents as potential contributors to sensitisation. No pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
Madecassic Acid
No known risks
A triterpene associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical madecassic acid is limited. Evidence for the related Centella ingredient family supports current cosmetic exposure when products are formulated to avoid sensitisation; no pregnancy-specific topical contraindication was identified in the reviewed material.
Sources: CIR: Safety Assessment of Centella asiatica-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-centella-asiatica-derived-ingredients-used-cosmetics-1
Squalane
No known risks
Lightweight emollient used to support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure levels.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Zinc PCA
No known risks
A zinc salt of pyrrolidone carboxylic acid used for skin conditioning, oil-control and antimicrobial support. Cosmetic safety reviewers concluded that the assessed zinc salts are safe in current cosmetic practices of use and concentration when formulated to be non-irritating. Zinc is an essential nutrient, but this entry assesses the low topical exposure from a finished cosmetic rather than supplements or medicinal doses. No pregnancy-specific topical concern was identified.
Sources: CIR: Safety Assessment of Zinc Salts as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-zinc-salts-used-cosmetics-1; CIR 146th Expert Panel Meeting final report record https://www.cir-safety.org/meeting/146th-cir-expert-panel-meeting
Butylene Glycol
No known risks
Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Pentylene Glycol
No known risks
Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Caprylyl/Capryl Glucoside
No known risks
This glucose-derived nonionic surfactant or emulsifier is used in cleansers and emulsions. The Cosmetic Ingredient Review concluded that alkyl glucosides are safe in current cosmetic use when formulated to be non-irritating; sensitive skin can still react to surfactants.
Sources: CIR: Safety Assessment of Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=9810a771-8e74-ec11-8943-0022482f06a6
Hydrogenated Lecithin
No known risks
Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.
Sources: Cosmetic Ingredient Review (US)
Ceramide NP
No known risks
Skin-identical barrier lipid used to support the stratum corneum and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Ceramides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Full recorded ingredient list
Water, Azelaic Acid, Propylene Glycol, Sodium Hydroxide, Dipropylene Glycol, 1,2-Hexanediol, Panthenol, Hydroxyethylcellulose, Betaine Salicylate, Glycerin, Biosaccharide Gum-1, Ethylhexylglycerin, Allantoin, Dipotassium Glycyrrhizate, Melia Azadirachta Leaf Extract, Camellia Sinensis Leaf Water, Sodium Hyaluronate, Melia Azadirachta Flower Extract, Niacinamide, Aloe Barbadensis Leaf Juice, Beta-Glucan, Centella Asiatica Extract, Centella Asiatica Leaf Extract, Centella Asiatica Root Extract, Madecassoside, Asiaticoside, Asiatic Acid, Madecassic Acid, Squalane, Zinc PCA, Butylene Glycol, Pentylene Glycol, Caprylyl/Capryl Glucoside, Hydrogenated Lecithin, Ceramide NP
Ingredient ratings refreshed 1 October 2026. Formulas vary by market and can change. Always compare with your packaging.
Questions about this assessment
Why does Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum have a Low risk rating?
The recorded formula includes 3 ingredient entries with risk flags: Azelaic Acid (Low risk), Betaine Salicylate (Low risk), Dipotassium Glycyrrhizate (Low risk). These are ingredient-level flags; they do not replace the stored product assessment or account for every formulation detail. The product score is a stored assessment, not a clinical safety guarantee.
Is this assessment based only on the azelaic acid?
No. Azelaic Acid appears in the recorded ingredient list, but this page shows the finished product's stored assessment and the available ratings for its other ingredients too. An assessment of one headline ingredient does not establish the suitability of every formula containing it.
Has every ingredient in Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum been assessed?
35 of 35 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
Does this assessment apply to my Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum?
Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.
Does this pregnancy assessment also establish breastfeeding suitability?
No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.
