Azelaic Acid
Low RiskAzelaic acid is used topically for acne and pigmentation. MotherToBaby reports that ACOG lists OTC azelaic acid among ingredients that can be used during pregnancy if needed. Product information for 20% azelaic acid states that adequate controlled pregnancy studies are lacking, reports reassuring animal data and estimates about 3.6% absorption after a single topical dose. MamaSkin retains Low Risk while avoiding a categorical “pregnancy-safe” claim.
Sources: MotherToBaby: Topical Acne Treatments https://www.ncbi.nlm.nih.gov/books/NBK582985/, Skinoren 20% cream product information https://www.medicines.org.uk/emc/product/285/smpc



