Anua PDRN Hyaluronic Acid 100 Moisturizing Cream

Lightweight emollient used to support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Protein-derived skin- and hair-conditioning ingredient used to support feel and hydration at the surface. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Humectant and skin-conditioning ingredient in the hyaluronate family. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

High-water-binding humectant used to support hydration at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

An aloe flower extract used for skin conditioning. Cosmetic safety reviewers concluded that supported Aloe barbadensis-derived ingredients are safe in current practices, with anthraquinone impurities controlled to no more than 50 ppm. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

A red-algae-derived extract used for skin conditioning, hydration or formula texture. Cosmetic safety reviewers concluded that the assessed red algae ingredients, including this extract, are safe in current practices of use and concentration. Cosmetic manufacturers should control naturally occurring contaminants such as heavy metals and arsenic.

A leaf extract used in soothing and skin-conditioning formulas. Cosmetic safety reviewers concluded that Centella asiatica leaf extract is safe at current cosmetic exposure when products are formulated to be non-sensitising. The assessment considered systemic and reproductive findings reported at substantially higher oral exposures; these did not establish a pregnancy-specific concern for ordinary topical cosmetic use. Centella constituents can still cause contact sensitivity in some people.

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

Polymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.

A glycerin dimer used to attract moisture and improve skin feel. Cosmetic safety reviewers assessed diglycerin with related polyglycerins and concluded that they are safe in current practices of use and concentration. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Large polymer thickener, stabilizer and texture ingredient used in gels, creams and sunscreens. Systemic exposure from topical cosmetic use is expected to be low, with no pregnancy- or breastfeeding-specific concern identified in reviewed cosmetic references.

Polymer thickener and stabiliser used in creams and sunscreens. Low systemic exposure expected.

A sugar-derived surfactant and emulsifier. Cosmetic safety reviewers concluded that alkyl glucosides, including C12-20 alkyl glucoside, are safe in current practices when formulated to be non-irritating.

Solvent and humectant used to improve texture and ingredient delivery in topical cosmetic formulas. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Chelating agent used to improve formula stability. Used at low levels and not associated with pregnancy-specific concerns.

A high-molecular-weight film-forming copolymer used in hair, oral-care and skin products. Cosmetic safety reviewers concluded that PVM/MA copolymer is safe in current practices of use and concentration. Absorption of the intact polymer is expected to be limited.

A triterpene glycoside associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical madecassoside is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but noted that madecassoside and related triterpenes may contribute to sensitisation, so products should be formulated to avoid sensitising concentrations. No pregnancy-specific topical contraindication was identified in the reviewed material.

Humectant and skin-conditioning ingredient in the hyaluronate family. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

A triterpene glycoside associated with Centella asiatica and used in soothing and skin-conditioning formulas. Pregnancy-specific evidence for isolated topical asiaticoside is limited. Cosmetic safety reviewers considered Centella-derived ingredients acceptable at current cosmetic exposure but noted that asiaticoside and related triterpenes may contribute to sensitisation. No pregnancy-specific topical contraindication was identified in the reviewed material.

Potassium hyaluronate is a salt of hyaluronic acid used as a surface humectant and skin conditioner. The Cosmetic Ingredient Review concluded that reviewed hyaluronates are safe in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.

Cationic hyaluronate derivative used as a humectant and conditioning ingredient. Reviewed topical hyaluronate safety sources support cosmetic use, with no pregnancy- or breastfeeding-specific concern identified.

Crosslinked hyaluronate humectant used to support hydration at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.

Modified hyaluronate humectant and skin-conditioning ingredient. Reviewed cosmetic safety sources support topical hyaluronate ingredients, with no pregnancy- or breastfeeding-specific concern identified for normal cosmetic use.

Long-chain fatty alcohol used as an emollient and thickener. This is not the same concern profile as simple drying alcohols; reviewed cosmetic safety sources support normal topical use.