Anua
Anua Azelaic Acid 10 Hyaluron Redness Soothing Serum
Low risk78/100
Anua
Heartleaf 70 Intense Calming Cream
General Moisturizers
Some ingredients carry a low-risk flag. Read the formulation context before deciding.
27 of 27 ingredients rated
Is it suitable during pregnancy?
MamaSkin rates the recorded formula for Anua Heartleaf 70 Intense Calming Cream as Low risk (79/100). Review the ingredient context and any manual-review explanation before deciding.
Why this rating? Manual-review explanation
Manual review 2026-07-13: The recorded formula was manually reviewed. This formula contains Cyclohexasiloxane, classified as low risk for consistency with MamaSkin's silicone policy. This does not indicate a known pregnancy contraindication; see the highlighted ingredient entry for its rationale and sources.
27 of 27 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
How we assess productsIngredient breakdown
The recorded formula, with evidence behind each rating. Unmatched ingredients are marked Not assessed in grey.
Ingredient ratings and evidence
Higher-risk flags first. Open an ingredient for evidence.
Cyclohexasiloxane
Low risk
A volatile cyclic silicone also known as D6, used for slip and quick-drying texture. Normal topical exposure is expected to be limited, but exact-ingredient pregnancy evidence is limited and cyclic siloxanes have route-specific toxicology and regulatory considerations. MamaSkin therefore classifies it as low risk rather than a pregnancy contraindication.
Sources: CIR: Safety Assessment of Cyclomethicone https://cir-safety.org/ingredient/cyclomethicone; ECHA: Octamethylcyclotetrasiloxane, Decamethylcyclopentasiloxane and Dodecamethylcyclohexasiloxane restriction https://echa.europa.eu/hot-topics/siloxanes
Houttuynia Cordata Extract 70%
No known risks
A heartleaf extract used for skin conditioning and soothing. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.
Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant ingredient-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.
Cetearyl Alcohol
No known risks
Fatty alcohol used as an emollient and thickener. Not the same as drying alcohols and not associated with pregnancy-specific concerns.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Glycerin
No known risks
Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Butylene Glycol
No known risks
Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Show all 27 ingredients
1,2-Hexanediol
No known risks
1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.
Sources: CIR; EU/UK Cosmetics Regulation
Dicaprylyl Ether
No known risks
A lightweight fatty ether used as an emollient and spreading agent. Cosmetic safety reviewers concluded that dicaprylyl ether is safe in current cosmetic use; reviewed developmental testing did not identify maternal or fetal toxicity and skin absorption was low. Safety for airbrush delivery was not established.
Sources: CIR: Safety Assessment of Fatty Ethers https://www.cir-safety.org/sites/default/files/FR_FattyEthers_122022.pdf
Caprylic/Capric Triglyceride
No known risks
Common emollient derived from fatty acids and glycerin. Used to soften skin and improve texture without pregnancy-specific concerns.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Hydrogenated Poly(C6-14 Olefin)
No known risks
A large hydrogenated hydrocarbon polymer used as an emollient and texture agent. Cosmetic safety reviewers assessed hydrogenated poly(C6-14 olefin) with cosmetic polyenes and concluded that the group is safe in current practices of use and concentration. Dermal absorption is expected to be limited by molecular size.
Sources: CIR: Safety Assessment of Polyene Group as Used in Cosmetics https://journals.sagepub.com/doi/10.1177/1091581820952385
Hydrogenated Polydecene
No known risks
Synthetic hydrocarbon emollient used to improve slip, cushion and moisture feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.
Sources: CIR cosmetic ingredient safety references for polydecenes/hydrocarbon emollients; EU CosIng / cosmetics regulatory inventory
Glyceryl Stearate Se
No known risks
Self-emulsifying form of glyceryl stearate used to stabilize creams and lotions. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific concern identified.
Sources: CIR cosmetic ingredient safety references for glyceryl stearate and self-emulsifying emulsifiers; EU CosIng / cosmetics regulatory inventory
Cetearyl Olivate
No known risks
Emollient ester/emulsifier used to improve skin feel and stabilise emulsions. Reviewed cosmetic safety sources support topical cosmetic use; the relevant practical caveat is formulation irritation potential rather than a pregnancy-specific concern.
Sources: CIR: Amended Safety Assessment of Alkyl Esters as Used in Cosmetics; CIR Quick Reference Table (Cetearyl Olivate); EU CosIng / cosmetics regulatory inventory
Sorbitan Olivate
No known risks
Olive-derived sorbitan ester used as an emulsifier and skin-conditioning ingredient. Reviewed cosmetic safety references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.
Sources: CIR: Safety Assessment of Sorbitan Esters as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Vegetable Oil
No known risks
A plant-derived fatty oil or butter used mainly as an emollient, conditioning ingredient or texture agent. Cosmetic safety reviewers concluded that the assessed plant-derived fatty acid oils are safe in current practices of use and concentration. This conclusion applies to cosmetic-grade fixed oils rather than similarly named volatile essential oils. Seed or food allergy may still matter for a susceptible person.
Sources: CIR: Safety Assessment of Plant-Derived Fatty Acid Oils as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=ad62ac6b-8e74-ec11-8943-0022482f06a6
Panthenol
No known risks
Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Hydrogenated Lecithin
No known risks
Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.
Sources: Cosmetic Ingredient Review (US)
Dipropylene Glycol
No known risks
Dipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Behenyl Alcohol
No known risks
Long-chain fatty alcohol used as an emollient and thickener. This is not the same concern profile as simple drying alcohols; reviewed cosmetic safety sources support normal topical use.
Sources: CIR: Final Report on the Safety Assessment of Cetearyl Alcohol, Cetyl Alcohol, Isostearyl Alcohol, Myristyl Alcohol, and Behenyl Alcohol; EU CosIng / cosmetics regulatory inventory
Ammonium Acryloyldimethyltaurate/Vp Copolymer
No known risks
Polymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Cetearyl Glucoside
No known risks
Sugar-based emulsifier used to stabilise creams and lotions. Reviewed cosmetic safety sources support topical cosmetic use; the relevant practical caveat is formulation irritation potential rather than a pregnancy-specific concern.
Sources: CIR: Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Cholesterol
No known risks
Skin-conditioning lipid used in barrier-support formulas, often alongside ceramides and fatty acids. Normal topical cosmetic use has no known pregnancy- or breastfeeding-specific concern identified in reviewed cosmetic references.
Sources: CIR cosmetic ingredient safety references for cholesterol and related sterols; EU CosIng / cosmetics regulatory inventory
Xanthan Gum
No known risks
Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.
Sources: European cosmetics regulatory framework
Adenosine
No known risks
Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Ceramide NP
No known risks
Skin-identical barrier lipid used to support the stratum corneum and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Ceramides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Glucose
No known risks
Simple sugar used as a humectant and skin-conditioning support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.
Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Water
No known risks
Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.
Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en
Ethylhexylglycerin
No known risks
Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.
Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)
Full recorded ingredient list
Houttuynia Cordata Extract 70%, Cetearyl Alcohol, Glycerin, Cyclohexasiloxane, Butylene Glycol, 1,2-Hexanediol, Dicaprylyl Ether, Caprylic/Capric Triglyceride, Hydrogenated Poly(C6-14 Olefin), Hydrogenated Polydecene, Glyceryl Stearate Se, Cetearyl Olivate, Sorbitan Olivate, Vegetable Oil, Panthenol, Hydrogenated Lecithin, Dipropylene Glycol, Behenyl Alcohol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Cetearyl Glucoside, Cholesterol, Xanthan Gum, Adenosine, Ceramide NP, Glucose, Water, Ethylhexylglycerin
Ingredient ratings refreshed 1 October 2026. Formulas vary by market and can change. Always compare with your packaging.
Questions about this assessment
Why does Anua Heartleaf 70 Intense Calming Cream have a Low risk rating?
Manual review 2026-07-13: The recorded formula was manually reviewed. This formula contains Cyclohexasiloxane, classified as low risk for consistency with MamaSkin's silicone policy. This does not indicate a known pregnancy contraindication; see the highlighted ingredient entry for its rationale and sources. The product score is a stored assessment, not a clinical safety guarantee.
Does a barrier-care product name establish pregnancy suitability?
No. This recorded formula contains Panthenol or Madecassoside, but a barrier-care claim does not establish the assessment of all its other ingredients. Read the individual ingredient evidence and any manual-review explanation, and compare the recorded list with your packaging.
Has every ingredient in Anua Heartleaf 70 Intense Calming Cream been assessed?
27 of 27 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.
Does this assessment apply to my Anua Heartleaf 70 Intense Calming Cream?
Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.
Does this pregnancy assessment also establish breastfeeding suitability?
No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.
