Anua Heartleaf 70 Intense Calming Cream by Anua
Anua

Anua Heartleaf 70 Intense Calming Cream

General Moisturizersmoisturisers

Safety score

Pregnancy-focused assessment

Low Risk79/100
Higher concernLower concern

Manual review 2026-07-13: The recorded formula was manually reviewed. This formula contains Cyclohexasiloxane, classified as low risk for consistency with MamaSkin's silicone policy. This does not indicate a known pregnancy contraindication; see the highlighted ingredient entry for its rationale and sources.

Formula and assessment check

Ingredient safety review updated 13 July 2026. Product formulas can change, so compare the ingredients shown here with the packaging you have.

Report a formula mismatch

MamaSkin assessment · 13 July 2026

Is Anua Heartleaf 70 Intense Calming Cream suitable during pregnancy?

MamaSkin currently classifies Anua Heartleaf 70 Intense Calming Cream as Low risk, with a stored score of 79/100. This is a precautionary classification, not an unqualified pregnancy-safe recommendation. Read the ingredient context and any manual-review explanation below.

Why this rating? Manual-review explanation

Manual review 2026-07-13: The recorded formula was manually reviewed. This formula contains Cyclohexasiloxane, classified as low risk for consistency with MamaSkin's silicone policy. This does not indicate a known pregnancy contraindication; see the highlighted ingredient entry for its rationale and sources.

27 of 27 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.

Ingredient breakdown

See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.

26

No known risks

1

Low risk

0

Medium risk

0

High risk

Ingredients

Ingredients with a higher risk flag appear first, followed by the rest of the formula.

Cyclohexasiloxane

Low Risk

A volatile cyclic silicone also known as D6, used for slip and quick-drying texture. Normal topical exposure is expected to be limited, but exact-ingredient pregnancy evidence is limited and cyclic siloxanes have route-specific toxicology and regulatory considerations. MamaSkin therefore classifies it as low risk rather than a pregnancy contraindication.

Sources: CIR: Safety Assessment of Cyclomethicone https://cir-safety.org/ingredient/cyclomethicone; ECHA: Octamethylcyclotetrasiloxane, Decamethylcyclopentasiloxane and Dodecamethylcyclohexasiloxane restriction https://echa.europa.eu/hot-topics/siloxanes

Houttuynia Cordata Extract 70%

No Known Risks

A heartleaf extract used for skin conditioning and soothing. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.

Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant ingredient-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.

Cetearyl Alcohol

No Known Risks

Fatty alcohol used as an emollient and thickener. Not the same as drying alcohols and not associated with pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Show all (27)

Glycerin

No Known Risks

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Butylene Glycol

No Known Risks

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

1,2-Hexanediol

No Known Risks

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

Dicaprylyl Ether

No Known Risks

A lightweight fatty ether used as an emollient and spreading agent. Cosmetic safety reviewers concluded that dicaprylyl ether is safe in current cosmetic use; reviewed developmental testing did not identify maternal or fetal toxicity and skin absorption was low. Safety for airbrush delivery was not established.

Sources: CIR: Safety Assessment of Fatty Ethers https://www.cir-safety.org/sites/default/files/FR_FattyEthers_122022.pdf

Caprylic/Capric Triglyceride

No Known Risks

Common emollient derived from fatty acids and glycerin. Used to soften skin and improve texture without pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Hydrogenated Poly(C6-14 Olefin)

No Known Risks

A large hydrogenated hydrocarbon polymer used as an emollient and texture agent. Cosmetic safety reviewers assessed hydrogenated poly(C6-14 olefin) with cosmetic polyenes and concluded that the group is safe in current practices of use and concentration. Dermal absorption is expected to be limited by molecular size.

Sources: CIR: Safety Assessment of Polyene Group as Used in Cosmetics https://journals.sagepub.com/doi/10.1177/1091581820952385

Hydrogenated Polydecene

No Known Risks

Synthetic hydrocarbon emollient used to improve slip, cushion and moisture feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for polydecenes/hydrocarbon emollients; EU CosIng / cosmetics regulatory inventory

Glyceryl Stearate Se

No Known Risks

Self-emulsifying form of glyceryl stearate used to stabilize creams and lotions. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific concern identified.

Sources: CIR cosmetic ingredient safety references for glyceryl stearate and self-emulsifying emulsifiers; EU CosIng / cosmetics regulatory inventory

Cetearyl Olivate

No Known Risks

Emollient ester/emulsifier used to improve skin feel and stabilise emulsions. Reviewed cosmetic safety sources support topical cosmetic use; the relevant practical caveat is formulation irritation potential rather than a pregnancy-specific concern.

Sources: CIR: Amended Safety Assessment of Alkyl Esters as Used in Cosmetics; CIR Quick Reference Table (Cetearyl Olivate); EU CosIng / cosmetics regulatory inventory

Sorbitan Olivate

No Known Risks

Olive-derived sorbitan ester used as an emulsifier and skin-conditioning ingredient. Reviewed cosmetic safety references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR: Safety Assessment of Sorbitan Esters as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Vegetable Oil

No Known Risks

A plant-derived fatty oil or butter used mainly as an emollient, conditioning ingredient or texture agent. Cosmetic safety reviewers concluded that the assessed plant-derived fatty acid oils are safe in current practices of use and concentration. This conclusion applies to cosmetic-grade fixed oils rather than similarly named volatile essential oils. Seed or food allergy may still matter for a susceptible person.

Sources: CIR: Safety Assessment of Plant-Derived Fatty Acid Oils as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=ad62ac6b-8e74-ec11-8943-0022482f06a6

Panthenol

No Known Risks

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

Hydrogenated Lecithin

No Known Risks

Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.

Sources: Cosmetic Ingredient Review (US)

Dipropylene Glycol

No Known Risks

Dipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

Behenyl Alcohol

No Known Risks

Long-chain fatty alcohol used as an emollient and thickener. This is not the same concern profile as simple drying alcohols; reviewed cosmetic safety sources support normal topical use.

Sources: CIR: Final Report on the Safety Assessment of Cetearyl Alcohol, Cetyl Alcohol, Isostearyl Alcohol, Myristyl Alcohol, and Behenyl Alcohol; EU CosIng / cosmetics regulatory inventory

Ammonium Acryloyldimethyltaurate/Vp Copolymer

No Known Risks

Polymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Cetearyl Glucoside

No Known Risks

Sugar-based emulsifier used to stabilise creams and lotions. Reviewed cosmetic safety sources support topical cosmetic use; the relevant practical caveat is formulation irritation potential rather than a pregnancy-specific concern.

Sources: CIR: Decyl Glucoside and Other Alkyl Glucosides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Cholesterol

No Known Risks

Skin-conditioning lipid used in barrier-support formulas, often alongside ceramides and fatty acids. Normal topical cosmetic use has no known pregnancy- or breastfeeding-specific concern identified in reviewed cosmetic references.

Sources: CIR cosmetic ingredient safety references for cholesterol and related sterols; EU CosIng / cosmetics regulatory inventory

Xanthan Gum

No Known Risks

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Sources: European cosmetics regulatory framework

Adenosine

No Known Risks

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Ceramide NP

No Known Risks

Skin-identical barrier lipid used to support the stratum corneum and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Ceramides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Glucose

No Known Risks

Simple sugar used as a humectant and skin-conditioning support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic use.

Sources: CIR: Safety Assessment of Monosaccharides, Disaccharides, and Related Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Water

No Known Risks

Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.

Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en

Ethylhexylglycerin

No Known Risks

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.

Questions about this assessment

Has every ingredient in Anua Heartleaf 70 Intense Calming Cream been assessed?

27 of 27 ingredient entries on this page have a recorded score, evidence summary and source text. That describes documentation coverage, not proof that the finished formula has been clinically tested during pregnancy.

Does this assessment apply to the Anua Heartleaf 70 Intense Calming Cream I have?

Only if the ingredient list on your packaging matches the recorded formula shown here. Formulas can differ by market and change over time. Compare the full list, not just the product name; report a mismatch if it differs.

Does this pregnancy assessment also establish breastfeeding suitability?

No. This page presents a pregnancy-focused product assessment. Do not infer a breastfeeding conclusion from its score or label; breastfeeding requires a separate assessment of the formula and how it is used.

How to use this assessment

The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.

MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.

Read the full methodology