
Anua Heartleaf 77 + Hyaluron Soothing Toner
Safety score
Pregnancy-focused assessment
No higher-risk ingredients were identified in MamaSkin's current assessment. Check the latest package before deciding.
Formula and assessment check
Ingredient safety review updated 24 November 2025. Product formulas can change, so compare the ingredients shown here with the packaging you have.
Report a formula mismatchIngredient breakdown
See how the listed formula falls across MamaSkin's pregnancy-focused risk bands.
24
No known risks
0
Low risk
0
Medium risk
0
High risk
Ingredients
Ingredients with a higher risk flag appear first, followed by the rest of the formula.
Water
No Known Risks1,2-Hexanediol
No Known Risks1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.
Sources: CIR; EU/UK Cosmetics Regulation
Show all (24)
Glycerin
No Known RisksGlycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Betaine
No Known RisksBetaine is a humectant/osmolyte used to support hydration and reduce irritation potential in formulas; it is considered low concern with no known pregnancy or breastfeeding risks in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Butylene Glycol
No Known RisksSolvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Isopentyldiol
No Known RisksA small alkane diol used as a solvent, humectant and preservative-support ingredient. Cosmetic safety reviewers concluded that alkane diols, including isopentyldiol, are safe in current practices of use and concentration. No pregnancy-specific concern was identified for normal topical cosmetic exposure.
Sources: CIR: Safety Assessment of Alkane Diols as Used in Cosmetics https://www.cir-safety.org/sites/default/files/ADIOLS062016rep.pdf
Panthenol
No Known RisksPanthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.
Sources: CIR; EU/UK Cosmetics Regulation
Acrylates/C10-30 Alkyl Acrylate Crosspolymer
No Known RisksPolymer thickener and stabiliser used in creams and sunscreens. Low systemic exposure expected.
Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)
Disodium EDTA
No Known RisksDisodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Tromethamine
No Known RiskspH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Tromethamine as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Centella Asiatica Extract
No Known RisksBotanical skin-conditioning ingredient used in soothing and barrier-support formulas. Reviewed cosmetic safety sources support current cosmetic use when formulated to be non-sensitising, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Centella asiatica-derived Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Arctium Lappa Root Extract
No Known RisksA burdock-root extract used for skin conditioning. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.
Sources: European Commission CosIng ingredient inventory; Cosmetic Ingredient Review botanical safety-assessment framework and relevant ingredient-family assessments. No ingredient-specific human pregnancy study of normal topical cosmetic use was identified.
Phellinus Linteus Extract
No Known RisksA mushroom-derived conditioning extract. No pregnancy-specific hazard was identified for normal topical exposure; source allergy remains possible.
Sources: European Commission CosIng; CIR biological-source ingredient framework; peer-reviewed fungal-extract literature.
Portulaca Oleracea Extract
No Known RisksA purslane extract used mainly for skin conditioning. Cosmetic safety reviewers concluded that Portulaca oleracea extract is safe in current cosmetic practices when formulated to be non-sensitising. Botanical irritation or allergy remains possible, but no pregnancy-specific concern was identified for normal topical use.
Sources: CIR: Safety Assessment of Portulaca oleracea-Derived Ingredients as Used in Cosmetics https://cir-reports.cir-safety.org/view-attachment/?id=5c0d093e-6947-f945-8d16-43dd820a5e63
Chamomilla Recutita Flower Extract
No Known RisksA German chamomile flower extract used for skin conditioning and soothing. Cosmetic safety reviewers concluded that Chamomilla recutita flower-derived ingredients are safe in current cosmetic use when formulated to be non-sensitizing. Chamomile can cause contact allergy in susceptible people, particularly those sensitive to plants in the Asteraceae family, but no pregnancy-specific concern is identified for normal topical cosmetic exposure.
Sources: CIR: Safety Assessment of Chamomilla Recutita-Derived Ingredients as Used in Cosmetics https://cir-safety.org/supplementaldoc/safety-assessment-chamomilla-recutita-derived-ingredients-used-cosmetics-0
Vitex Agnus-Castus Extract
No Known RisksSodium Hyaluronate
No Known RisksSodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.
Sources: CIR; EU/UK Cosmetics Regulation
Hydroxypropyltrimonium Hyaluronate
No Known RisksCationic hyaluronate derivative used as a humectant and conditioning ingredient. Reviewed topical hyaluronate safety sources support cosmetic use, with no pregnancy- or breastfeeding-specific concern identified.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Hydrolyzed Hyaluronic Acid
No Known RisksHumectant and skin-conditioning ingredient in the hyaluronate family. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Sodium Acetylated Hyaluronate
No Known RisksModified hyaluronate humectant and skin-conditioning ingredient. Reviewed cosmetic safety sources support topical hyaluronate ingredients, with no pregnancy- or breastfeeding-specific concern identified for normal cosmetic use.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Hyaluronic Acid
No Known RisksHigh-water-binding humectant used to support hydration at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Sodium Hyaluronate Crosspolymer
No Known RisksCrosslinked hyaluronate humectant used to support hydration at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory
Potassium Hyaluronate
No Known RisksPotassium hyaluronate is a salt of hyaluronic acid used as a surface humectant and skin conditioner. The Cosmetic Ingredient Review concluded that reviewed hyaluronates are safe in current cosmetic use, with no pregnancy- or breastfeeding-specific concern identified for normal topical exposure.
Sources: CIR: Safety Assessment of Hyaluronates as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-hyaluronates-used-cosmetics
Formulations can change without notice. For the most accurate result, compare this list with your packaging and scan the exact ingredient label in MamaSkin when you repurchase.
How to use this assessment
The risk band is the primary conclusion. The score adds detail within that band and should not be used to compare products as if a one-point difference were clinically meaningful.
MamaSkin provides pregnancy-focused information, not medical advice. Your midwife, GP, pharmacist or dermatologist should take priority when your circumstances differ from typical cosmetic use.


