Anua PDRN Hyaluronic Acid Hydrating Capsule Mist

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

An acetylated amino-acid derivative used for skin conditioning. CIR included Acetyl Glutamine in its safe-as-used conclusion for amino-acid alkyl amides when products are formulated to be non-irritating. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

A plant-derived polysaccharide used to thicken and stabilise formulas. Cosmetic safety reviewers concluded that agar is safe in current practices. Loose powder should not be deliberately inhaled.

Allantoin is a soothing skin protectant commonly used to help reduce irritation and support comfort, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

An aloe flower extract used for skin conditioning. Cosmetic safety reviewers concluded that supported Aloe barbadensis-derived ingredients are safe in current practices, with anthraquinone impurities controlled to no more than 50 ppm. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

A botanical extract, juice or water used primarily for skin conditioning, moisturising, soothing or antioxidant support. Direct pregnancy studies of the named cosmetic material were not identified. No reproductive or developmental hazard was identified for normal topical exposure to a compliant finished cosmetic; oral herbal or medicinal use is outside this classification.

A mineral-derived colourant, absorbent or texture ingredient. Purity and avoiding respirable exposure from loose powders or sprays are the practical formulation considerations. Dermal absorption is expected to be limited, and no reproductive or developmental hazard was identified for normal non-inhaled topical cosmetic use.

Sugar-derived humectant used to support hydration, often as part of saccharide blends. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

aureobasidium pullulans ferment is a fermentation-derived or microbial lysate cosmetic conditioning material. The assessment applies to the defined non-live cosmetic ingredient rather than live organisms or oral supplements. No pregnancy-specific concern was identified for normal topical use; formulation purity and sensitivity remain relevant.

A colour additive used in cosmetics. FDA lists caramel and beta-carotene as permitted cosmetic colour additives, including for eye-area and general cosmetic use, subject to applicable identity, purity and manufacturing requirements. No pregnancy-specific concern was identified from normal topical cosmetic exposure.

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

A common inorganic electrolyte used to control viscosity, stabilise a formula or condition skin. At cosmetic concentrations these salts do not present a pregnancy-specific concern; concentrated formulas can still sting damaged or very sensitive skin.

A processed cosmetic ferment, extract or fermentation-derived material used for conditioning, moisturising or formula support. It is not equivalent to applying an unspecified live culture. Available cosmetic safety assessments do not identify a pregnancy- or breastfeeding-specific hazard for normal topical use, assuming appropriate identity, preservation and microbial-quality controls.

Common emollient derived from fatty acids and glycerin. Used to soften skin and improve texture without pregnancy-specific concerns.

Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.

A high-molecular-weight polymer used for film formation, texture or stabilisation. Meaningful dermal absorption is expected to be limited and no reproductive or developmental concern was identified for normal topical use.

Cellulose-derived thickener and binder used to stabilise texture. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Skin-identical barrier lipid used to support the stratum corneum and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

pH adjuster used in small amounts to maintain product stability. Not associated with pregnancy-specific concerns.

An ivy-gourd fruit extract used for skin conditioning and antioxidant support. No pregnancy- or breastfeeding-specific hazard was identified for normal topical cosmetic exposure. Direct ingredient-specific pregnancy studies were not identified, so this assessment does not extend to oral supplements or medicinal use.

Copper-binding carrier peptide also known as GHK-Cu, used topically in cosmetic skin-renewal, anti-aging, barrier-support and hair/scalp products. Reviewed literature describes topical cosmetic use and does not identify a pregnancy- or breastfeeding-specific risk signal for normal topical use. This assessment does not apply to injectable copper peptides or oral peptide/copper supplementation.

A red-algae-derived extract used for skin conditioning, hydration or formula texture. Cosmetic safety reviewers concluded that the assessed red algae ingredients, including this extract, are safe in current practices of use and concentration. Cosmetic manufacturers should control naturally occurring contaminants such as heavy metals and arsenic.

Turmeric root extract is used for antioxidant and skin-conditioning effects. Pregnancy cautions relate mainly to concentrated oral supplements; normal topical cosmetic exposure is substantially smaller. The principal topical concern is irritation or allergy in sensitive users.

A plant-part extract used for skin conditioning, soothing, fragrance or antioxidant support. No pregnancy-specific systemic signal was identified for normal topical cosmetic exposure. This assessment does not extend to essential oils, oral herbal products or medicinal doses, and botanical sensitivity remains possible.

A functional cosmetic ingredient used for preservation support, pH control, chelation, solvent action or formula stability. Concentrated material may irritate skin or eyes, but no pregnancy-specific reproductive or developmental hazard was identified for normal use in a compliant finished cosmetic.

Dipropylene glycol is used as a solvent and carrier in cosmetics; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

A high-molecular-weight carbohydrate gum produced by microbial fermentation and used for hydration, texture or film formation. Cosmetic safety reviewers concluded that the assessed microbial polysaccharide gums are safe in current practices of use and concentration. Dermal absorption of the intact polymers is expected to be limited.

An ethoxylated glycerin humectant used to retain moisture and improve product texture. The Cosmetic Ingredient Review assessed glycerin ethoxylates including Glycereth-26 for current cosmetic use; available evidence does not identify a pregnancy- or breastfeeding-specific concern from normal topical exposure.

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Plant-derived emollient oil used to soften skin and support formula texture. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

A soybean seed extract used for skin conditioning. Cosmetic safety reviewers concluded that the assessed Glycine soja-derived ingredients are safe in current practices. Soy sensitivity remains possible.

Helianthus annuus (sunflower) seed oil is a common emollient rich in fatty acids and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

A plant-derived oil or hydrogenated wax used mainly as an emollient and skin-conditioning ingredient. Cosmetic safety reviewers concluded that these named sea buckthorn, tea seed, jojoba and grape seed ingredients are safe in current practices of use and concentration. Plant allergy remains possible.

High-water-binding humectant used to support hydration at the skin surface. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.

Protein-derived skin- and hair-conditioning ingredient used to support feel and hydration at the surface. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Humectant and skin-conditioning ingredient in the hyaluronate family. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

Hydroxyacetophenone is used as an antioxidant and preservative-support ingredient; it is generally considered low concern in topical cosmetic use with no known pregnancy or breastfeeding risks at typical concentrations.

A humectant that helps skin and hair retain water. Cosmetic safety reviewers concluded that hydroxyethyl urea is safe in current cosmetic use when formulated to be non-irritating; reproductive and developmental data reviewed for the assessment did not identify a pregnancy-specific concern from normal topical exposure.

Inorganic salt used as a viscosity-control, bulking or stabilizing ingredient in cosmetics. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Neem flower extract is used as a botanical skin-conditioning ingredient. A high-dose oral rat study altered the oestrous cycle and ovulation but did not show anti-implantation, abortifacient, or teratogenic effects. That oral dose does not establish a hazard from normal topical cosmetic exposure.

Neem leaf extract is used topically for skin conditioning and antimicrobial support. Reproductive concerns reported for concentrated neem seed preparations, intrauterine exposure, or high oral doses do not establish a hazard from normal topical cosmetic exposure to a leaf extract.

This plant-derived fatty oil or butter is used as an emollient and skin-conditioning ingredient. The Cosmetic Ingredient Review concluded that assessed plant-derived fatty acid oils are safe as used in cosmetics; individual plant allergy and ingredient purity remain practical considerations.

Holy basil leaf extract is used for antioxidant and skin-conditioning purposes. Available warnings and pharmacology largely concern oral herbal use. No pregnancy-specific systemic hazard was identified for normal topical exposure to a compliant cosmetic, although botanical sensitivity remains possible.

A fatty ester, lipid-derived emulsifier or emollient used for texture and skin conditioning. These materials have low expected systemic exposure, and no pregnancy-specific reproductive or developmental hazard was identified for normal topical cosmetic use.

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Humectant and preservative booster. Considered safe for cosmetic use with low systemic exposure.

Silicone emollient used to improve slip, gloss, and water resistance. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

A common inorganic electrolyte used to control viscosity, stabilise a formula or condition skin. At cosmetic concentrations these salts do not present a pregnancy-specific concern; concentrated formulas can still sting damaged or very sensitive skin.

A cosmetic functional ingredient used for conditioning, texture or formula support. Available cosmetic-use information did not identify a reproductive or developmental hazard from normal topical exposure.

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

pyrus malus juice is a botanical-derived cosmetic conditioning ingredient. The reviewed identity is not a concentrated essential oil or an oral herbal preparation. Available cosmetic evidence and expected topical exposure did not identify a pregnancy-specific contraindication, although botanical irritation or allergy remains possible.

pyrus malus seed oil is a fixed plant oil used mainly as an emollient. CIR's plant-derived oil assessment supports cosmetic use, with refining, oxidation control and possible residual allergenic proteins remaining relevant. No pregnancy-specific concern was identified for normal topical exposure; this does not extend to concentrated essential oils or ingestion.

Plant-derived emollient oil used to soften skin and improve formula feel. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

An alkaline mineral salt used for deodorising, buffering and mild abrasion. Cosmetic safety reviewers concluded that sodium bicarbonate is safe in current practices. It can irritate sensitive or freshly shaved skin in some formulas.

Sodium chloride is used to adjust viscosity and texture in formulations; topical cosmetic use is considered low concern with no known pregnancy or breastfeeding risks.

Buffering and chelating ingredient used to control pH and formulation stability. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Amino-acid-derived emulsifier and skin-conditioning support ingredient. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

A fruit, seed or food-plant extract used for skin conditioning and antioxidant support. No pregnancy-specific signal was identified for the low topical exposure expected from a finished cosmetic. Direct pregnancy studies are generally unavailable, and botanical allergy remains possible.

Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Sugar alcohol humectant used to help maintain hydration and improve skin feel. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.