Estée Lauder Advanced Night Repair Synchronized Multi-Recovery Complex Serum

A non-live bacterial fermentation lysate used for skin conditioning. It is not the same as applying live bacteria. Available cosmetic safety information and the nature of the processed material do not identify a pregnancy-specific concern for normal topical exposure.

A small polyethylene glycol used as a humectant and solvent. Cosmetic safety reviewers concluded that PEG-8 is safe at current cosmetic concentrations, but PEG ingredients should not be used on damaged skin and manufacturing impurities must be controlled. No pregnancy-specific concern was identified for compliant topical use.

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

An ethoxylated silicone used as a humectant, emulsifier and skin-conditioning ingredient. Cosmetic safety assessments of PEG-modified silicones support current topical uses, with low expected absorption of the intact material and control of manufacturing impurities.

A glucose-derived humectant and conditioning ingredient. Cosmetic safety reviewers concluded that methyl gluceth-20 is safe as used in cosmetics; reviewed skin testing did not indicate sensitisation. No pregnancy-specific concern was identified for normal topical cosmetic exposure.

An ethoxylated glycerin humectant used to retain moisture and improve product texture. The Cosmetic Ingredient Review assessed glycerin ethoxylates including Glycereth-26 for current cosmetic use; available evidence does not identify a pregnancy- or breastfeeding-specific concern from normal topical exposure.

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

A yeast-derived ferment, filtrate or extract used for skin conditioning. Cosmetic safety reviewers concluded that cosmetic ingredients derived from the reviewed yeast species are safe in current practices; this record applies to the standardized cosmetic INCI material, not an unspecified live culture.

Ferment-derived skin-conditioning ingredient used in microbiome-support and soothing formulas. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

A Roman chamomile flower extract or oil used for skin conditioning and fragrance. Cosmetic safety reviewers concluded that Anthemis nobilis-derived ingredients are safe in current practices when formulated to be non-sensitising. People allergic to plants in the daisy family may be more likely to react.

An algae- or seaweed-derived ingredient used for skin conditioning, moisturising or texture support. Composition and trace mineral content vary by source. No pregnancy-specific hazard was identified for normal topical cosmetic exposure; this does not assess oral seaweed supplements.

Methylxanthine used in cosmetics (e.g., de-puffing/firming and antioxidant support). No pregnancy-specific contraindications are identified for topical cosmetic use.

Emulsifier and skin-conditioning ingredient composed of phospholipids. Not associated with pregnancy-specific concerns.

A terpene alcohol used for skin conditioning and soothing. Cosmetic safety reviewers reaffirmed bisabolol as safe at current cosmetic concentrations, and reproductive and developmental testing did not identify adverse effects. Bisabolol can increase skin penetration, so formulators should consider the safety of other ingredients in the same product.

Lightweight emollient used to support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Glycerin is a widely used humectant that supports hydration and the skin barrier, with a long safety record and no known pregnancy or breastfeeding concerns in topical cosmetic use.

Humectant and preservative booster used to support product stability. Low systemic exposure expected from topical cosmetic use.

Hydrogenated emulsifier used to support skin barrier feel. Not associated with pregnancy-specific concerns.

Tocopheryl acetate (vitamin E derivative) is used as an antioxidant and skin-conditioning ingredient; it is considered low concern in topical use with no known pregnancy or breastfeeding risks at cosmetic concentrations.

Polymer thickener used to create gel textures. Large-molecule ingredient with negligible systemic absorption.

Chelating agent used to stabilise formulations; minimal dermal absorption and no known pregnancy or breastfeeding risks at typical cosmetic concentrations.

Natural polysaccharide thickener used for stability and texture. Not associated with pregnancy-specific concerns.

Preservative widely used in foods and cosmetics. Considered safe at regulated concentrations with low systemic exposure from topical use.

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

A Colour Index or lake name for a regulated cosmetic colour additive. Permitted product areas differ by colour, and certified colours must meet applicable identity and purity specifications. No pregnancy-specific concern was identified for compliant topical cosmetic use.