Peach 77 Niacin Enriched Cream

Niacinamide (vitamin B3) is widely used for barrier support and tone/texture benefits, and is generally considered safe in pregnancy and breastfeeding when used topically at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

1,2-Hexanediol is commonly used as a solvent and preservative booster; topical exposure is low and it has no known pregnancy or breastfeeding concerns at cosmetic concentrations, though very sensitive skin may occasionally react.

Sources: CIR; EU/UK Cosmetics Regulation

Volatile emollient/solvent used for slip, quick-dry texture and makeup wear. Reviewed cosmetic ingredient references support normal topical use, with no pregnancy- or breastfeeding-specific topical concern identified.

Sources: CIR: Safety Assessment of Isoparaffins as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Ferment-derived skin-conditioning ingredient used in microbiome-support and soothing formulas. Reviewed cosmetic safety sources support current cosmetic use, with no pregnancy- or breastfeeding-specific topical concern identified in the material reviewed.

Sources: CIR: Safety Assessment of Lactobacillus Ferment Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Solvent and humectant used to improve texture and ingredient solubility. Low systemic exposure expected from topical cosmetic use.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Panthenol (pro-vitamin B5) is used for soothing and barrier support and is generally well tolerated, with no known pregnancy or breastfeeding concerns in topical cosmetic use.

Sources: CIR; EU/UK Cosmetics Regulation

An emulsifier built from polyglycerin, methyl glucose and stearic-acid components, used to stabilise creams and improve texture. Exact pregnancy-specific data are limited. Cosmetic safety reviewers concluded that related methyl glucose esters and polyglyceryl fatty-acid esters are safe in current cosmetic use when formulated to be non-irritating. No pregnancy-specific topical concern was identified by applying those related-group assessments to ordinary cosmetic exposure.

Sources: CIR: Safety Assessment of Methyl Glucose Polyethers and Esters https://www.cir-safety.org/supplementaldoc/safety-assessment-methyl-glucose-polyethers-and-esters-used-cosmetics; CIR: Safety Assessment of Polyglyceryl Fatty Acid Esters https://cir-safety.org/sites/default/files/PGlyFE092016FR.pdf

A silicone resin used as a film former, texture enhancer and opacifying ingredient in makeup, sunscreen and skin care. The Cosmetic Ingredient Review concluded that polysilsesquioxanes including Polymethylsilsesquioxane are safe in current cosmetic use. Available evidence does not identify a pregnancy- or breastfeeding-specific concern for normal topical cosmetic exposure.

Sources: CIR: Safety Assessment of Polysilsesquioxanes as Used in Cosmetics (Final Report) https://cir-safety.org/sites/default/files/PLYSIL122017FR.pdf

Synthetic hydrocarbon emollient used to improve slip, cushion and moisture feel. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for polydecenes/hydrocarbon emollients; EU CosIng / cosmetics regulatory inventory

Peach fruit extract is Prunus persica fruit extract; the common-name wording does not change the preparation. No pregnancy-specific harm has been identified from ordinary formulated topical use. Direct pregnancy studies are limited; this assessment concerns fruit pulp extract, not peach seed oil, kernel extract or concentrated oral preparations. Cosmetic purity and fruit-allergy precautions matter.

Sources: https://cosmileeurope.eu/ro/inci/ingredient/13333/prunus-persica-fruit-extract, https://www.cir-safety.org/sites/default/files/Botanical%20Decision%20Tree%20CIR%20June%202012%202.pdf

Peach flower extract is used as a skin-conditioning botanical. No pregnancy-specific harm has been identified for ordinary formulated topical use, although direct pregnancy studies are limited. This assessment applies to the flower extract and does not extend to peach kernels, medicinal ingestion or concentrated preparations. Botanical sensitivity remains possible.

Sources: https://kcia.or.kr/cid/search/ingd_view.php?no=559, https://www.cir-safety.org/supplementaldoc/quick-reference-table-december-2025

Sodium hyaluronate (hyaluronic acid salt) is used for hydration and cushioning, with very low systemic absorption from topical use and no known pregnancy or breastfeeding concerns at cosmetic concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

A collagen preparation used for skin and hair conditioning. Cosmetic safety reviewers concluded that soluble collagen and related connective-tissue proteins are safe in current practices, subject to source and impurity controls that exclude prohibited cattle materials. Protein sensitivity remains possible in susceptible people.

Sources: CIR: Safety Assessment of Skin and Connective Tissue-Derived Proteins and Peptides https://cir-safety.org/sites/default/files/tsupep092017final.pdf

Jojoba-derived wax esters used as emollients, texture agents and skin-conditioning ingredients. Reviewed cosmetic ingredient references do not identify a pregnancy- or breastfeeding-specific concern for normal topical use.

Sources: CIR cosmetic ingredient safety references for jojoba-derived ingredients/wax esters; EU CosIng / cosmetics regulatory inventory

The final CIR methicone assessment includes the exact identity in its safe-as-used conclusion.

Sources: https://www.cir-safety.org/sites/default/files/FAR_Methicones_032022.pdf

Polymer thickener used to stabilise emulsions. Large-molecule ingredient with low systemic absorption.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Water (Aqua) is the standard purified water used as a cosmetic solvent. It has no pregnancy-specific risk in normal topical use.

Sources: https://pubchem.ncbi.nlm.nih.gov/compound/Water, https://single-market-economy.ec.europa.eu/sectors/cosmetics/cosmetic-ingredient-database/cosing-glossary-ingredients_en

A high-molecular-weight silicone polymer used for film forming, smoothing and skin or hair conditioning. The Cosmetic Ingredient Review concluded that Dimethiconol and its assessed derivatives are safe in current cosmetic use. Its polymeric nature limits skin penetration, and available evidence does not identify a pregnancy- or breastfeeding-specific concern for normal topical exposure.

Sources: CIR: Safety Assessment of Dimethiconol and its Esters and Reaction Products; International Journal of Toxicology 36(Suppl. 3):31-50 (2017) https://cir-safety.org/ingredient/dimethiconol

Polymer thickener and stabiliser used in creams and sunscreens. Low systemic exposure expected.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Hydroxyacetophenone is used as an antioxidant and preservative-support ingredient; it is generally considered low concern in topical cosmetic use with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

pH adjuster and buffer used to stabilise formulations. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Tromethamine as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Preservative booster and skin-conditioning agent. Considered safe for cosmetic use with low systemic exposure when used as intended.

Sources: Scientific Committee on Consumer Safety (EU); Cosmetic Ingredient Review (US)

Solvent and humectant commonly used in leave-on products. Not associated with pregnancy-specific concerns at cosmetic exposure levels.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Skin-conditioning ingredient commonly used in leave-on skincare. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Adenosine Ingredients as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

Disodium EDTA is a chelating agent used to improve formula stability and performance; it is considered low concern in topical cosmetic use, with no known pregnancy or breastfeeding risks at typical concentrations.

Sources: CIR; EU/UK Cosmetics Regulation

A vitamin B ingredient or derivative used for skin or hair conditioning. These vitamins are normal nutrients and no pregnancy-specific concern was identified for the small topical exposure expected from a finished cosmetic. This assessment does not replace guidance about oral supplements or therapeutic doses.

Sources: NIH Office of Dietary Supplements vitamin fact sheets https://ods.od.nih.gov/factsheets/list-all/; CIR: Panthenol, Pantothenic Acid and Derivatives safety assessment https://www.cir-safety.org/supplementaldoc/safety-assessment-panthenol-pantothenic-acid-and-derivatives-used-cosmetics-1

A yeast-derived ferment, filtrate or extract used for skin conditioning. Cosmetic safety reviewers concluded that cosmetic ingredients derived from the reviewed yeast species are safe in current practices; this record applies to the standardized cosmetic INCI material, not an unspecified live culture.

Sources: CIR: Yeast-derived ingredients final assessment, June 2024; Galactomyces Ferment Filtrate conclusion; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

Vitamin E antioxidant used to protect oils and support the skin barrier. Not associated with pregnancy-specific concerns at cosmetic exposure.

Sources: Cosmetic Ingredient Review (US); Scientific Committee on Consumer Safety (EU)

Skin-identical barrier lipid used to support the stratum corneum and reduce dryness. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Ceramides as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

A sugar, polysaccharide or related carbohydrate used for hydration, texture or formula support. No reproductive or developmental concern was identified for normal topical cosmetic exposure.

Sources: European Commission CosIng ingredient inventory; CIR safety assessments of saccharides and naturally derived polymers as used in cosmetics.

Polysaccharide carrier and bulking agent used for texture and delivery support. Reviewed cosmetic safety sources support normal topical use, with no pregnancy- or breastfeeding-specific topical signal identified in the material reviewed.

Sources: CIR: Safety Assessment of Polysaccharide Gums as Used in Cosmetics; EU CosIng / cosmetics regulatory inventory

A plant-derived protein or peptide mixture used mainly for hair and skin conditioning. Cosmetic safety reviewers concluded that the assessed plant-derived proteins and peptides are safe in current practices. Protein allergy remains possible in susceptible people.

Sources: CIR: Safety Assessment of Plant-Derived Proteins and Peptides as Used in Cosmetics https://www.cir-safety.org/supplementaldoc/safety-assessment-plant-derived-proteins-and-peptides-used-cosmetics-0

A yeast-derived ferment, filtrate or extract used for skin conditioning. Cosmetic safety reviewers concluded that cosmetic ingredients derived from the reviewed yeast species are safe in current practices; this record applies to the standardized cosmetic INCI material, not an unspecified live culture.

Sources: CIR: Yeast-derived ingredients final assessment, June 2024; Galactomyces Ferment Filtrate conclusion; December 2025 Quick Reference Table https://cir-safety.org/sites/default/files/QRT-Update-Dec2025.pdf

A non-live bacterial fermentation lysate used for skin conditioning. It is not the same as applying live bacteria. Available cosmetic safety information and the nature of the processed material do not identify a pregnancy-specific concern for normal topical exposure.

Sources: CIR yeast and bacterial ferment strategy and safety assessments; European Commission CosIng ingredient inventory for Bifida Ferment Lysate.